Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Genome Editing Technique

Sdn Type

Displaying 17 results

Traits related to improved food/feed quality

Altered gliadin levels resulting in improved end-use quality and reduced gluten epitopes associated with celiac disease. Gliadins are important for wheat end-use traits.
( Liu et al., 2023 )
SDN1
CRISPR/Cas
China Agricultural University, China
Research Centre for Cereal and Industrial Crops, Italy
Reduces phytic acid (anti-nutrient) and improves iron and zinc accumulation in wheat grains. Biofortification.
( Ibrahim et al., 2021 )
SDN1
CRISPR/Cas
Quaid-i-Azam University Islamabad
National Agricultural Research Centre, Pakistan
Increased protein content and increased grain weight. Increase in grain protein content has a positive effect on flour protein content and gluten strength, two quality parameters.
( Zhang et al., 2018 )
SDN1
CRISPR/Cas
Chinese Academy of Sciences
University of Chinese Academy of Sciences
Shandong Normal University, China
Reduced gluten content. Coeliac disease is an autoimmune disorder triggered in genetically predisposed individuals by the ingestion of gluten proteins.
( Sánchez-León,et al., 2017 )
SDN1
CRISPR/Cas
Instituto de Agricultura Sostenible (IASCSIC), Spain
University of Minnesota, USA
Modification of starch composition, structure and properties. Foods with a high amylose content (AC) and resistant starch (RS) offer potential to improve human health and lower the risk of serious non-infectious diseases.
( Li et al., 2020 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences (CAAS)
Nanjing Agricultural University, China
Increased iron (Fe) and magnesium (Mn) content for biofortification: increasing the intrinsic nutritional value of crops.
(Connorton et al., 2017)
SDN1
CRISPR/Cas
John Innes Centre
University of East Anglia, UK
Increased grain number per spikelet.
( Zhang et al., 2019 )
SDN1
CRISPR/Cas
University of Missouri
South Dakota State University
University of California
Donald Danforth Plant Science Center, USA
University of Bristol, UK
Reduce allergen proteins. Structural and metabolic proteins, like α-amylase/trypsin inhibitors are involved in the onset of wheat allergies (bakers' asthma) and probably Non-Coeliac Wheat Sensitivity (NCWS).
( Camerlengo et al., 2020 )
SDN1
CRISPR/Cas
University of Tuscia, Italy
Rothamsted Research, UK
Impasse Thérèse Bertrand-Fontaine, France
Reduced accumulation of free asparagine, the precursor for acrylamide. Acrylamide is a contaminant which forms during the baking, toasting and high-temperature processing of foods made from wheat.
( Raffan et al., 2021 )
SDN1
CRISPR/Cas
Rothamsted Research
University of Bristol, UK

Traits related to industrial utilization

Significantly longer seed dormancy period, may result in reduced pre-harvest sprouting of grains on spikes.
( Abe et al., 2019 )
SDN1
CRISPR/Cas
Institute of Crop Science
Okayama University
Yokohama City University
Institute of Agrobiological Sciences
Obihiro University of Agriculture and Veterinary Medicine, Japan
New red-grained and pre-harvest sprouting (PHS)-resistant wheat varieties with elite agronomic traits. PHS reduces yield and grain quality, additionally the red pigment of the grain coat contains proanthocyanidins, which have antioxidant activity and thus health-promoting properties.
( Zhu et al., 2022 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences
Fujian Academy of Agricultural Sciences
Henan University
Shenzhen Research Institute of Henan university
Taiyuan University of Technology
Southern University of Science and Technology, China
University of Edinburgh, UK
Generating male sterility lines (MLS). Using MLS in hybrid seed production reduces costs and ensures high purity of the varieties because it does not produce pollen and has exserted stigmas.
( Zhang et al., 2023 )
SDN1
CRISPR/Cas
Shandong Academy of Agricultural Sciences
Key Laboratory of Wheat Biology and Genetic Improvement on North Yellow and Huai River Valley
National Engineering Laboratory for Wheat and Maize
Chinese Academy of Agricultural Sciences, China
Rapid generation of male sterile (MS) bread wheat. MS is an important tool in creating hybrid crop varieties that provide a yield advantage over traditional varieties by harnessing heterosis.
( Singh et al., 2021 )
SDN1
CRISPR/Cas
DuPont Pioneer, USA
Generating male sterility lines (MLS). Using MLS in hybrid seed production reduces costs and ensures high purity of the varieties because it does not produce pollen and has exserted stigmas.
( Li et al., 2020 )
SDN1
CRISPR/Cas
Peking University Institute of Advanced Agricultural Sciences
Peking University
Beijing Key Laboratory of Plant Gene Resources and Biotechnology for Carbon Reduction and Environmental Improvement, China
Fertility recovery of male sterility in wheat lines with excelling agronomic and economic traits for breeding purpose, as male-sterile plants cannot be used for selection.
( Tang et al., 2021 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences
China Agricultural University, China
Generation of male-sterile hexaploid wheat lines for use in hybrid seed production. The development and adoption of hybrid seed technology have led to dramatic increases in agricultural productivity.
( Okada et al., 2019 )
SDN1
CRISPR/Cas
The University of Adelaide, Australia
Huaiyin Normal University, China
Complete male sterility. The generation, restoration, and maintenance of male sterile lines are the key issues for large-scale commercial hybrid seed production.
( Li et al., 2020 )
SDN1
CRISPR/Cas
Peking University Institute of Advanced Agricultural Sciences
School of Advanced Agriculture Sciences and School of Life Sciences
Beijing Key Laboratory of Plant Gene Resources and Biotechnology for Carbon Reduction and Environmental Improvement, China