Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Genome Editing Technique

Displaying 12 results

Traits related to biotic stress tolerance

Mutants were compromised in infectivity of Phytophthora palmivora, a destructive oomycete plant pathogen with a wide host range
( Pettongkhao et al., 2022 )
SDN1
CRISPR/Cas
Prince of Songkla University, Thailand
University of Hawaii at Manoa
East-West Center, USA
Sainsbury Laboratory Cambridge University (SLCU), UK
Viral resistance: reduced cassava brown streak disease (CBSD) symptom severity and incidence. CBSD threatens cassava production in West Africa and is a major constraint on cassava production in East and Central Africa.
(Gomez et al., 2019)
SDN1
CRISPR/Cas
University of California
Donald Danforth Plant Science Center, USA
Fungal resistance: Reduced pathogenicity to the oomycete Phytophthora palmivora, a destructive pathogen that infects all parts of papaya plants. Increased papain sensitvity of in-vitro growth. Papaya fruits contain papain, a cysteine protease that mediates plant defense against pathogens and insects.
(Gumtow et al., 2018)
SDN1
CRISPR/Cas
University of Hawaii at Manoa, USA
Visualization of the early stages of Cassava bacterial blight (CBB) infection in vivo. CBB is caused by Xanthomonas axonopodis pv. Manihotis.
( Veley et al., 2021 )
SDN2
CRISPR/Cas
Donald Danforth Plant Science Center, USA
National Root Crops Research Institute, Nigeria
Viral resistance: Attenuated infection symptoms and reduced viral RNA accumulation, specific for the cucumber mosaic virus (CMV) or tobacco mosaic virus (TMV).
(Zhang et al., 2018)
SDN1
CRISPR/Cas
South China Agricultural University, China
University of Missouri, USA
Viral resistance: increased resistance against Tobacco Mosaic Virus (TMV).
(Jogam et al., 2023)
SDN1
CRISPR/Cas
Kakatiya University
Center of Innovative and Applied Bioprocessing (DBT-CIAB), India
University of Minnesota
East Carolina University, USA

Traits related to improved food/feed quality

Ultra-low nicotine level
( Burner et al., 2022 )
SDN1
CRISPR/Cas
North Carolina State University, USA
Attenuated toxic cyanogen production. Cassava produces toxic cyanogenic compounds and requires food processing for safe consumption.
( Gomez et al., 2021 )
SDN1
CRISPR/Cas
University of California
Donald Danforth Plant Science Center
Lawrence Berkeley National Laboratory
Okinawa Institute of Science and Technology Graduate University
Chan-Zuckerberg BioHub, USA

Traits related to industrial utilization

Accumulate low levels of alkaloids. Nicotine is the most abundant alkaloid produced in tobacco plants. Switching to cigarettes containing levels of nicotine below the level of sustaining an addiction response will smoke less and/or find it easier to quit. Possibly, the US Food and Drug Administration (FDA) may mandate such reductions in future cigarette products.
( Smith et al., 2022 )
SDN1
CRISPR/Cas
North Carolina State University, USA

Traits related to herbicide tolerance

Herbicide tolerance: glyphosate
(Hummel et al., 2017)
SDN3
CRISPR/Cas
Donald Danforth Plant Science Center, St. Louis, USA

Traits related to product color/flavour

Reduced citrate content. Citrate is a common primary metabolite which often characterizes fruit flavour.
( Fu et al., 2023 )
SDN1
CRISPR/Cas
Zhejiang University, China
University of Florida, USA
The New Zealand Institute for Plant &
Food Research Limited (Plant &
Food Research) Mt Albert
University of Auckland, New Zealand
Albino phenotype.
( Brewer et al., 2022 )
SDN1
CRISPR/Cas
University of Florida, USA