Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the current and future applications of genome editing in crops, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crops.

The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about genome editing applications in crops. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.

Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.

Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop developed for market-oriented agricultural production as a result of a genome editing.

This database will be regularly updated. Please contact us via the following webpage (https://www.eu-sage.eu/contact) in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing.

This work has been supported by Task Force Planet Re-Imagine Europa (https://reimagine-europa.eu/area/planet)

Genome Editing Technique

Plant

Sdn Type

Displaying 18 results

Traits related to industrial utilization

Nicotine-free tobacco.
( Schachtsiek et al., 2019 )
SDN1
CRISPR/Cas
TU Dortmund University, Germany
Glycoproteins without plant-specific glycans. Plants or plant cells can be used to produce pharmacological glycoproteins, for example antibodies or vaccines. However these proteins carry N-glycans with plant-typical residues [β(1,2)-xylose and core α(1,3)-fucose]. This plant-specific glycans can greatly impact the immunogenicity, allergenicity, or activity of the protein.
( Mercx et al., 2017 )
SDN1
CRISPR/Cas
Université catholique de Louvain
Université de Liège, Belgium
Establishment of maternal haploid induction. Doubled haploid technology is used to obtain homozygous lines in a single generation. This technique significantly accelerates the crop breeding trajectory.
( Zhong et al., 2022 )
SDN1
CRISPR/Cas
China Agricultural University, China
Wageningen University and Research, The Netherlands
Accumulate low levels of alkaloids. Nicotine is the most abundant alkaloid produced in tobacco plants. Switching to cigarettes containing levels of nicotine below the level of sustaining an addiction response will smoke less and/or find it easier to quit. Possibly, the US Food and Drug Administration (FDA) may mandate such reductions in future cigarette products.
( Smith et al., 2022 )
SDN1
CRISPR/Cas
North Carolina State University, USA
Cytoplasmic male sterility.
( Chang et al., 2022 )
SDN1
CRISPR/Cas
Northwest Institute of Plateau Biology Chinese Academy of Sciences, China

Traits related to biotic stress tolerance

Viral resistance: highly resistant to viral infection with beet severe curly top virus (BSCTV), a geminivirus that can cause serious damage to many crop plants.
(Ji et al., 2015)
SDN1
CRISPR/Cas
University of Chinese Academy of Sciences, China
Viral resistance: Attenuated infection symptoms and reduced viral RNA accumulation, specific for the cucumber mosaic virus (CMV) or tobacco mosaic virus (TMV).
(Zhang et al., 2018)
SDN1
CRISPR/Cas
South China Agricultural University, China
University of Missouri, USA
Viral resistance: resistance to potato virus Y (PVY), one of the most economically and scientifically important plant viruses, causing damaging diseases of cultivated tobacco around the world.
(Ruyi et al., 2021)
SDN1
CRISPR/Cas
Mudanjiang Teachers College
Jilin Normal University
Mudanjiang Tobacco Research Institute, China
Viral resistance: to Cotton Leaf Curl Kokhran Virus, causing Cotton leaf curl disease (CLCuD), a very devastating and prevalent disease. CLCuD causes huge losses to the textile and other industries.
(Hamza et al., 2021)
SDN1
CRISPR/Cas
National Institute for Biotechnology and Genetic Engineering, Pakistan
Increased resistance to drought stress by enhancing antioxidant capacity and defence system.
( Gao et al., 2022 )
SDN1
CRISPR/Cas
Henan Agricultural University
China Tobacco Sichuan Industrial Co., China
Enhanced resistance to powdery mildew.
( Wang et al., 2022 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences Institute of Tobacco Research, China
Enhanced Potato virus Y (PVY) resistance.
( Le et al., 2022 )
SDN1
CRISPR/Cas
Vietnam Academy of Science and Technology, Vietnam
University of Edinburgh, UK

Traits related to abiotic stress tolerance

Improved Cadmium (Cd)-tolerance by reducing the Cd transport from vacuole to cytosol in tobacco leaves.
( Jia et al., 2022 )
SDN1
CRISPR/Cas
Henan Agricultural University
Xiamen University, China

Traits related to improved food/feed quality

Ultra-low nicotine level
( Burner et al., 2022 )
SDN1
CRISPR/Cas
North Carolina State University, USA
Improved cadmium tolerance by reducing the Cd transport from vacuole to cytosol in tobacco leaves.
( Jia et al., 2022 )
SDN1
CRISPR/Cas
Henan Agricultural University
Xiamen University, China
Fine-tuning sugar content. Consumer preference varies along regional, cultural, and age lines, thus the solution is to create a continuum of phenotypic “taste” changes
( Xing et al., 2020 )

BE
Chinese Academy of Sciences
China Agricultural University, China

Traits related to increased plant yield and growth

Faster seedling growth.
( Zhou et al., 2018 )
SDN1
CRISPR/Cas
University of Maryland, USA

Traits related to product color/flavour

Albino phenotype.
( Wilson et al., 2019 )
SDN1
CRISPR/Cas
NIAB EMR, UK