Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Genome Editing Technique

Plant

Displaying 36 results

Traits related to biotic stress tolerance

Visualization of the early stages of Cassava bacterial blight (CBB) infection in vivo. CBB is caused by Xanthomonas axonopodis pv. Manihotis.
( Veley et al., 2021 )
SDN2
CRISPR/Cas
Donald Danforth Plant Science Center, USA
National Root Crops Research Institute, Nigeria
Viral resistance: reduced cassava brown streak disease (CBSD) symptom severity and incidence. CBSD threatens cassava production in West Africa and is a major constraint on cassava production in East and Central Africa.
(Gomez et al., 2019)
SDN1
CRISPR/Cas
University of California
Donald Danforth Plant Science Center, USA
Rapid detection of Sclerotium rolfsii, the causal agent of stem and root rot disease. This technique is effective for identification of pathogens, with potential for on-site testing.
( Changtor et al., 2023 )
SDN1
CRISPR/Cas
Naresuan University, Thailand

Traits related to abiotic stress tolerance

Improved drought and salt tolerance.
( Zhang et al., 2023 )
SDN1
CRISPR/Cas
Northeast Forestry University
Chinese Academy of Forestry
Chinese Academy of Sciences
Nanjing Forestry University, China

Traits related to improved food/feed quality

High-amylose content (up to 56% in apparent amylose content) and resistant starch (up to 35%).
( Luo et al., 2021 )
SDN1
CRISPR/Cas
Chinese Academy of Sciences
Shanghai Sanshu Biotechnology Co.,
Guangxi Subtropical Crops Research Institute, China
Removing the major allergen to tackle food allergies.
( Assou et al., 2021 )
SDN1
CRISPR/Cas
Leibniz Universität Hannover
Technische Universität Braunschweig, Germany
Attenuated toxic cyanogen production. Cassava produces toxic cyanogenic compounds and requires food processing for safe consumption.
( Gomez et al., 2021 )
SDN1
CRISPR/Cas
University of California
Donald Danforth Plant Science Center
Lawrence Berkeley National Laboratory
Okinawa Institute of Science and Technology Graduate University
Chan-Zuckerberg BioHub, USA
Reduce or eliminate amylose content in root starch. Amylose influences the physicochemical properties of starch during cooking and processing.
( Bull et al., 2018 )
SDN1
CRISPR/Cas
Institute of Molecular Plant Biology, Switzerland
Increased vitamin C content, increased oxidation stress tolerance and increased ascorbate content.
( Zhang et al., 2018 )
SDN1
CRISPR/Cas
Chinese Academy of Sciences, China
Seeds low in glucosinolate content and other plant parts high in glucosinolate levels. Glucosinolates are anti-nutrients that can cause reduced performance and impairment of kidney and liver functions of livestock, they also play a role in plant defence.
( Mann et al., 2023 )
SDN1
CRISPR/Cas
National Institute of Plant Genome Research
University of Delhi South Campus, India

Traits related to increased plant yield and growth

High temperature germination. Large increases in the maximum temperature for seed germination to allow for the cultivation of the crop in production areas with higher temperature.
( Bertier et al., 2018 )
SDN1
CRISPR/Cas
University of California, USA
Bushy phenotype and increased tiller production.
( Liu et al., 2017 )
SDN1
CRISPR/Cas
Iowa State University, USA
Improve biomass yield and salinity tolerance.
( Guan et al., 2020 )
SDN1
CRISPR/Cas
China Agricultural University
Shandong institute of agricultural sustainable development
Beijing Sure Academy of Biosciences, China
Oklahoma State University, USA
Increased seed number per silique, which increases the mustard yield per plant.
( Wang et al., 2021 )
SDN1
CRISPR/Cas
Huazhong Agricultural University, China
Induced erect leaf habit and shoot growth for a more efficient light penetration into lower canopy layers.
( Fladung et al., 2021 )
SDN1
CRISPR/Cas
Thünen Institute of Forest Genetics, Germany
Enhanced photosynthesis and decreased leaf angles for improved plant architecture and high yields.
( An et al., 2022 )
SDN1
CRISPR/Cas
Huazhong Agricultural University, China
Increased leaf yield of lettuce by delaying the onset of flowering.
( Choi et al., 2022 )
SDN1
CRISPR/Cas
Korea Research Institute of Bioscience and Biotechnology
Korea University of Science and Technology, South Korea
Significantly improved photosynthesis and decreased leaf angles. The plant architecture is ideal for dense planting.
( An et al., 2022 )
SDN1
CRISPR/Cas
Huazhong Agricultural University, China
Increased formation of adventitious roots (ARs). The formation of ARs is extremely important to the large-scale vegetative propagation of elite genotypes in many economically important woody species.
( Ran et al., 2023 )
SDN1
CRISPR/Cas
Nanjing Forestry University
Yangzhou University, China
Delay in the appearance of flower buds and increased yield.
( Beracochea et al., 2023 )
SDN1
CRISPR/Cas
Consejo Nacional de Investigaciones Científicas Y Técnicas (CONICET)
Instituto Nacional de Tecnología Agropecuaria (INTA), Argentina
More and longer lateral roots, more xylem and increased development of secondary vascular tissues: plants more suitable for biofuel and bioenergy production.
(An et al., 2023)
SDN1
CRISPR/Cas
Zhejiang A &
F University, China
Butterhead plant architecture.
( Xie et al., 2023 )
SDN1
CRISPR/Cas
Huazhong Agricultural University
Wuhan Academy of Agricultural Sciences, China
Late flowering phenotype.
( Liu et al., 2024 )
SDN1
CRISPR/Cas
China Agricultural University, China

Traits related to industrial utilization

35% reduction in lignin. Fourfold increase in cellulose-to-glucose conversion upon limited saccharification. Efficient saccharification is hindered by the presence of lignin in the secondary-thickened cell walls.
( de Vries et al., 2021 )
SDN1
CRISPR/Cas
Ghent University
VIB Center for Plant Systems Biology, Belgium
Reduced lignin content and increased sugar release upon saccharification.
( De Meester et al., 2021 )
SDN1
CRISPR/Cas
Ghent University
VIB Center for Plant Systems Biology, Belgium
Improved saccharification efficiency by an altered cell wall architecture.
( Nayeri et al., 2022 )
SDN1
CRISPR/Cas
Shahid Beheshti University
University of Tabriz, Iran
Tailoring poplar lignin without yield penalty. Reduced recalcitrance.
( De Meester et al., 2020 )
SDN1
CRISPR/Cas
Ghent University
VIB Center for Plant Systems Biology
VIB Metabolomics Core, Belgium
Bio-fuel production: Reduced lignin content and improved sugar release.
(Park et al., 2017)
SDN1
CRISPR/Cas
Noble Research Institute, USA
Reduced lignin content and S (syringyl lignin)/G (guaiacyl lignin) (S/G) ratio alteration to reduce cell wall recalcitrance and improve bioethanol production. Lignin is a major component of secondary cell walls and contributes to the recalcitrance problem during fermentation.
( Park et al., 2021 )
SDN1
CRISPR/Cas
The Samuel Roberts Noble Foundation
BioEnergy Science Center
University of Tennessee, USA
Accelerate flowering, a rare event under glasshouse conditions. Modified starch.
( Bull et al., 2018 )
SDN3
CRISPR/Cas
Institute of Molecular Plant Biology, Switzerland
Stem wood discoloration due to lignin reduction.
( Zhou et al., 2015 )
SDN1
CRISPR/Cas
University of Georgia, USA
Complete reproductive sterility to prevent the spread of highly domesticated, exotic or genetically modified organisms into wild populations.
( Azeez et al., 2021 )
SDN1
CRISPR/Cas
Michigan Technological University, USA
Modified wood composition with traits desirable for fiber pulping and lower carbon emissions. The edited wood could bring efficiencies, bioeconomic opportunities and environmental benefits.
( Sulis et al., 2023 )
SDN1
CRISPR/Cas
North Carolina State University
University of Illinois at Urbana-Champaign, USA
Beihua University
Northeast Forestry University, China

Traits related to herbicide tolerance

Herbicide tolerance: glyphosate
(Hummel et al., 2017)
SDN3
CRISPR/Cas
Donald Danforth Plant Science Center, St. Louis, USA

Traits related to product color/flavour

Albino phenotype
( Fan et al., 2015 )
SDN1
CRISPR/Cas
Southwest University
Chinese Academy of Sciences, China

Traits related to storage performance

Extended root shelf-life, which decreases its wastage.
( Mukami et al., 2023 )
SDN1
CRISPR/Cas
Kenyatta University
Jomo Kenyatta University of Agriculture Technology
Pwani University Kilifi, Kenya