Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Genome Editing Technique

Plant

Sdn Type

Displaying 28 results

Traits related to biotic stress tolerance

Fungal resistance: increased resistance to Erysiphe necator, causing powdery mildew in grape cultivar. The pathogen infects all green tissues and berries, leading to dramatic losses in yield and berry quality.
(Malnoy et al., 2016)
SDN1
CRISPR/Cas
Fondazione Edmund Mach, Italy
ToolGen Inc.
Institute for Basic Science
Seoul National University, South Korea
Viral resistance: Resistance against Grapevine leafroll-associated virus 3 (GLRaV-3), which is one of the causal agents of grapevine leafroll disease (GLD). GLD severely impacts grapevine production.
(Jiao et al., 2022)

CRISPR/Cas
Northwest A&
F University, China
Fungal resistance: enhanced resistance to powdery mildew (Erysiphe necator), a major fungal disease, threatening one of the most economically valuable horticular crops.
(Wan et al., 2020)
SDN1
CRISPR/Cas
Ministry of Agriculture, China
Northwest A&
F University
University of Maryland College Park, USA
Fungal resistance: increased resistance to Botrytis cinerea.
(Wang et al., 2018)
SDN1
CRISPR/Cas
Northwest A&
F University and Ministry of Agriculture, China
Viral resistance: increased resistance to turnip mosaic virus (TuMV).
(Lee et al., 2023)
SDN1
CRISPR/Cas
Rural Development Administration
Advanced Institute for Science and Technology, South Korea
North Carolina State University, USA
Fungal resistance: effective reduction of susceptibility against downy mildew by increasing salicylic acid levels. The pathogen can devastate individual vineyards and in some cases also affect production from entire regions.
(Giacomelli et al., 2023)
SDN1
CRISPR/Cas
Research and Innovation Centre
Fondazione Edmund Mach, Italy
Enza Zaden
Hudson River Biotechnology, The Netherlands
Fungal resistance: Decreased susceptibility to Plasmopara viticola, the causing agent of the grapevine downy mildew.
(Djennane et al., 2023)
SDN1
CRISPR/Cas
Université de Strasbourg
Institut Jean-Pierre Bourgin (IJPB), France
Fungal resistance: reduced symptoms caused by a powedry mildew infection.
(Olivares et al., 2021)
SDN1
CRISPR/Cas
National Institute of Agriculture Research, Chile

Traits related to abiotic stress tolerance

Regulated circadian clock: circadian clock measures and conveys day length information to control rhythmic hypocotyl growth in photoperiodic conditions, to achieve optimal fitness. Mutants showed longer hypocotyls, lower core circadian clock morning component mRNA and protein levels, and a shorter circadian rhythm. Exposure to high temperature due to global warming.
(Kim et al., 2022)
SDN1
CRISPR/Cas
National Institute of Agricultural Science
Korea Polar Research Institute
Seoul National University College of Medicine, South Korea
Reduced stomatal density. Intrinsic water-use efficiency was significantly impacted under both well-watered and drought conditions, making reduced stomatal density as a preferable trait.
( Clemens et al., 2022 )
SDN1
CRISPR/Cas
University of California
San Diego State University, USA
Removal of harmful pericarp character of weedy rice while increasing drought tolerance. Weedy rice has the potential of domestication into direct-seeding rice with strong drought tolerance.
( Kong et al., 2023 )
SDN1
CRISPR/Cas
Nanjing Agricultural University, China

Traits related to improved food/feed quality

Low tartaric acid.
( Ren et al., 2016 )
SDN1
CRISPR/Cas
University of Chinese Academy of Sciences
Chinese Academy of Sciences, China
Promoted anthocyanin accumulation. Anthocyanins are plant secondary metabolites with a variety of biological functions.
( Tu et al., 2022 )
SDN1
CRISPR/Cas
Northwest A&
F University, China
Glucoraphanin(GR)-enriched broccoli. Broccoli contains important nutritional components and beneficial phytochemicals. GR, a major glucosinolate (GSL), protects the body against several chronic diseases.
( Kim et al., 2022 )
SDN1
CRISPR/Cas
Sejong University
Jeonbuk National University
Korea Research Institute of Bioscience and Biotechnology
Asia Seed Company Limited, South Korea
Enhanced oil composition. Increased oleic acid content and significant decreases in the less desirable polyunsaturated fatty acids, linoleic acid (i.e. a decrease from ~16% to <4%) and linolenic acid (a decrease from ~35% to <10%).
( Jiang et al., 2016 )
SDN1
CRISPR/Cas
University of Nebraska
University of California, USA
Increased levels of oleic acid and alpha-linolenic acid. Camelina is a low-input oilseed crop. It is necessary to ameloriate fatty acid composition in oils to meet different application requirements.
( Ozseyhan et al., 2018 )
SDN1
CRISPR/Cas
Montana State University, USA
Increased levels of oleic acid, decreased levels of fatty acids.
( Morineau et al., 2016 )
SDN1
CRISPR/Cas
Université Paris-Saclay, France
Lower oil content and altered fatty acid composition. Most commercially produced oil seeds synthesize only a relatively small range of fatty acids, offering limited functionality.
( Aznar-Moreno et al., 2017 )
SDN1
CRISPR/Cas
Kansas State University, USA
Glossy green phenotype and reduced cuticular wax load.
( Liu et al., 2023 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences
Hunan Agricultural University
Tianjin Kernel Vegetable Research Institute, China
Reduced glucosinolate levels. Glucosinolates are anti-nutrients that can cause reduced performance and impairment of kidney and liver functions of livestock.
( Hölzl et al., 2022 )
SDN1
CRISPR/Cas
University of Bonn
Leibniz Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben, Germany

Traits related to increased plant yield and growth

Early flowering. Certain mutants also showed following phenotypes: determinate flowering, shorter stature and/or basal branching.
(Bellec et al., 2022)
SDN1
CRISPR/Cas
Université Paris-Saclay, France
Delayed bolting.
( Shin et al., 2022 )
SDN1
CRISPR/Cas
Kyung Hee University, South Korea
Delayed bolting.
( Shin et al., 2022 )
SDN1
CRISPR/Cas
Kyung Hee University, South Korea
Early bolting and flowering.
( Wang et al., 2023 )
SDN1
CRISPR/Cas
South China Agricultural University, China

Traits related to industrial utilization

Early-flowering.
( Jeong et al., 2021 )
SDN1
CRISPR/Cas
Department of Biological Science
Seoul National University
Chungnam National University
Institute for Basic Science
Kangwon National University
Kyunghee University, South Korea
Delayed flowering time.
( Hong et al., 2021 )
SDN1
CRISPR/Cas
National Institute of Agricultural Sciences, South Korea
Increased monounsaturated fatty acid contents (MUFAs). Due to their higher thermal-oxidative stability and viscosity relative to other common fatty acids, MUFAs are preferred for industrial uses, for example as biolubricants and biodiesel fuels.
( Lee et al., 2021 )
SDN1
CRISPR/Cas
National Institute of Agricultural Sciences
Korea Advanced Institute of Science and Technology
Chonnam National University
Plant Engineering Research Institute, South Korea
Enhanced oil accumulation in the seed.
( Cai et al., 2024 )
SDN1
CRISPR/Cas
Brookhaven National Laboratory
Stony Brook University
Montana State University, USA