genome search | EU-SAGE

Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 122 results

Traits related to biotic stress tolerance

Highly significant reduction in susceptibility to fire blight, caused by the bacterium Erwinia amylovora. Apple is one of the most cultivated fruit crops throughout the temperate regions of the world.
( Pompili et al., 2020 )

SDN1
CRISPR/Cas

Università degli Studi di Udine
Fondazione Edmund Mach, Italy

Bacterial resistance: Increased resistance to Erwinia amylovora, causing fire blight disease that threatens the apple and a wide range of ornamental and commercial Rosaceae host plants.
(Malnoy et al., 2016)

SDN1
CRISPR/Cas

Fondazione Edmund Mach, Italy
ToolGen Inc.
Institute for Basic Science
Seoul National University, South Korea

Fungal resistance: Increased resistance to Phytophthora sojae, a pathogen severely impairing soybean production.
(Yu et al., 2021)

SDN1
CRISPR/Cas

Northeast Agricultural University
Chinese Academy of Agricultural Sciences
Shanghai Jiao Tong University
Jilin Academy of Agricultural Science
Jiamusi Branch Academy of Heilongjiang Academy of Agricultural Sciences
Heilongjiang Academy of Agricultural Sciences, China

High level of powdery mildew resistance while maintaining normal crop
growth and yields.
( Li et al., 2022 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences, China

Robust rust resistance to pandemic stripe rust caused by Puccinia striiformis (Pst) without growth and yield penalty.
( Wang et al., 2022 )

SDN1
CRISPR/Cas

Northwest A&
F University
Chinese Academy of Sciences, China

Resistance against leaf chewing insects: leaf-chewing insects cause yield loss and reduce seed quality in soybeans
(Zhang et al., 2022)

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Huazhong Agricultural University
Henan Agricultural University, China

Resistance to Phytophthora sojae, which severely impairs soybean production.
( Yu et al., 2022 )

SDN1
CRISPR/Cas

Northeast Agricultural University
Chinese Academy of Agricultural Sciences
Jilin Academy of Agricultural Science
Shanghai Jiao Tong University
Jiamusi Branch Academy of Heilongjiang Academy of Agricultural Sciences, China

Viral resistance: increased resistance against wheat yellow mosaic virus (WYMV) without yield penalty. WYMV results in severe yield losses in hexaploid wheat.
(Kan et al., 2023)

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences (CAAS)
Agricultural Sciences Institute in Jiangsu Lixiahe Area, China

Fungal resistance: increased resistance against the fungus Puccinia striiformis f. sp. tritici (Pst). Wheat stripe rust is caused by Pst and is one of the most destructive wheat diseases, resulting in significant losses to wheat production worldwide.
(He et al., 2022)

SDN1
CRISPR/Cas

Northwest A&
F University
Hebei Agri cultural University, China

Fungal resistance to Oidium neolycopersici, causing powdery mildew, one of the most important diseases limiting the production of wheat.
( Wang et al., 2014 )

SDN1
TALENs

Chinese Academy of Sciences, China

Fungal resistance to Oidium neolycopersici, causing powdery mildew, one of the most important diseases limiting the production of wheat.
( Zhang et al., 2017 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences, China

Fungal resistance: resistance to Fusarium graminearum. Fusarium head blight (FHB) is an economically important disease, affecting both yield and grain quality of maize, wheat and barley.
(Brauer et al., 2020)

SDN1
CRISPR/Cas

Ottawa Research and Development Centre, Canada

Oomycete resistance: increased resistance against soybean root rot disease caused by Phytophthora sojae.
(Liu et al., 2023)

SDN1
CRISPR/Cas

Nanjing Agricultural University, China

Viral resistance: Strong barley yellow dwarf virusses (BYDV) resistance without negative effects on plant growth under field conditions. BYDV threatens efficient and stable production of wheat, maize, barley and oats.
(Wang et al., 2023)

SDN1
CRISPR/Cas

Henan Agricultural University
The Shennong Laboratory
Chinese Academy of Agricultural Sciences, China

Sensitive detection of two fungal pathogens (Diaporthe aspalathi and Diaporthe caulivora) that cause soybean stem canker. The method requires minimal equipment as well as training and shows potential for on-site screening.
( Sun et al., 2023 )

SDN1
CRISPR/Cas

Chinese Academy of Inspection and Quarantine
Shenyang Agricultural University
Huangpu Customs Technology Center
Technical Center of Hangzhou Customs
Dalian University, China

Fungal resistance: Enhanced resistance to powdery mildew, a fungal disease causing great losses in soybean yield and seed quality.
(Bui et al., 2023)

SDN1
CRISPR/Cas

Institute of Biotechnology
University of Science and Technology of Hanoi
Vietnam Academy of Science and Technology
Vietnam Academy of Agriculture Science, Vietnam
Washington University in St. Louis
University of Missouri, USA

Nematode resistance: resistance against soybean cyst nematode. Plant-parasitic nematode pests result in billions of dollars in realized annual losses worldwide.
(Usovsky et al., 2023)

SDN1
CRISPR/Cas

University of Missouri
University of Georgia
Beltsville Agricultural Research Center, USA

Fungal resistance: stripe rust resistance, caused by Puccinia striiformis f. sp. tritici. In appropriate environmental conditions and susceptible varieties, stripe rust can cause huge grain yield and quality loss.
(Li et al., 2023)

SDN1
CRISPR/Cas

Fudan University
Chinese Academy of Sciences
University of the Chinese Academy of Sciences
China Agricultural University
Guangzhou University
School of Life Science
Shandong Academy of Agricultural Sciences
Ministry of Agriculture
National Engineering Research Center for Wheat and Maize
Sichuan Agricultural University
Nanjing Agricultural University, China
Université Paris Cité
Université Paris-Saclay, France

Fungal resistance: enhanced resistance against rust caused by Puccinia striiformis f. sp. tritici and powdery mildew caused by Blumeria graminis f. sp. tritici., while also increasing yield.
(Liu et al., 2024)

SDN1
CRISPR/Cas

Southwest University
Yangtze University, China
University of Cologne, Germany
University of Maryland

Nematode resistance: Enhanced resistance to more virulent soybean cyst nematode (SCN). SCN is the most devastating post to soybean crop yields in the US.
(Wang et al., 2024)

SDN1
CRISPR/Cas

Henan Agricultural University
University of South Carolina, China

Early on site detection of Phytophthora root rot, caused by Phytophthora sojae.
( Li et al., 2024 )

SDN1
CRISPR/Cas

Hainan University
Shanghai Jiao Tong University
China Agricultural University
Post-Entry Quarantine Center for Tropical Plant, China

Fungal resistance: Assay for rapid detection of Diaporthe aspalathi, causal agent of Southern stem canker, which causes huge losses of soybean worldwide.
(Dong et al., 2024)

SDN1
CRISPR/Cas

Hainan University
Sanya Institute of China Agricultural University, China

Viral resistance: resistance against Soybean mosaic virus, which is a very common and destructive pathogenic virus.
(Gao et al., 2024)

SDN1
CRISPR/Cas

Nanjing Agricultural University
Beijing Vocational College of Agriculture
China Agricultural University
Shenyang Agricultural University, China

Viral resistance: enhanced resistance against wheat dwarf virus, which is a causal agent of wheat viral disease and can significantly impact wheat production worldwide.
(Yuan et al., 2024)

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Northwest A&
F University, China

Norwegian Institute of Bioeconomy Research, Norway

Traits related to abiotic stress tolerance

Drought tolerance.
( Kim D et al,. 2018 )

SDN1
CRISPR/Cas

Montana State University, USA

Drought and salt tolerance.
( Curtin et al., 2018 )

SDN1
CRISPR/Cas

University of Minnesota, USA
The University of Newcastle, Australia

Enhanced salinity stress tolerance.
( Wang et al., 2021 )

SDN1
CRISPR/Cas

Northeast Normal University
Jilin Academy of Agricultural Sciences
Linyi University
Chinese Academy of Sciences, China

Drought resistance.
( Zhang et al., 2022 )

SDN1
CRISPR/Cas

Jilin Agricultural University, China

Reduced cuticle permeability and enhanced drought tolerance.
( He et al., 2022 )

SDN1
CRISPR/Cas

Northwest A&
F University
USA
University of British Columbia, Canada

Increased drought tolerance.
( Abdallah et al., 2022 )

SDN1
CRISPR/Cas

Cairo University, Egypt
Crop Improvement and Genetics Unit, USA

Reduced arsenic content and increased arsenic tolerance. Arsenic is toxic to organisms and elevated its accumulation may pose health risks to humans.
( Wang et al., 2023 )

SDN1
CRISPR/Cas

Henan Agricultural University
Chinese Academy of Sciences
Henan Agricultural University, China

Increased root length, which can restore good performance under water stress.
( Gabay et al., 2023 )

SDN1
CRISPR/Cas

University of California
Howard Hughes Medical Institute, USA
University of Haifa, Israel
Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET)
Universidad Nacional de San Martín (UNSAM), Argentina
Fudan University
China Agricultural University, China
Karolinska Institutet, Sweden

Enhanced drought tolerance.
( Wang et al., 2023 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China
International Maize and Wheat Improvement Center, Mexico

Fruits insensitive to the effectss of high temperature stress and with reduced browning phenotype caused by high temperatures.
( Wang et al., 2023 )

SDN1
CRISPR/Cas

Northwest A &
F University
College of Horticultural Science and Engineering, China

Enhanced salt tolerance and alkali resistance among other resistances.
( Luo et al., 2024 )

SDN1
CRISPR/Cas

Northeast Agricultural University/Key Laboratory of Soybean Biology of the Chinese Education Ministry
Keshan Branch of Heilongjiang Academy of Agricultural Sciences
Harbin Normal University, China

Enhanced salt tolerance.
( Chen et al., 2024 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Chinese Academy of Agricultural Sciences
Tianjin Academy of Agricultural Sciences
Chinese Academy of Agricultural Sciences
Minzu University of China
Hebei Academy of Agriculture and Forestry Science, China

Traits related to improved food/feed quality

Reducing polyunsaturated fatty acids content and increased content of monounsaturated fatty acids. High levels of polyunsaturated fatty acids in natural soybean oil renders the oil susceptible to the development of unpalatable flavors and trans fatty acids.
( Fu et al., 2022 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China

Altered gliadin levels resulting in improved end-use quality and reduced gluten epitopes associated with celiac disease. Gliadins are important for wheat end-use traits.
( Liu et al., 2023 )

SDN1
CRISPR/Cas

China Agricultural University, China
Research Centre for Cereal and Industrial Crops, Italy

Reduced phytic acid content in soybean seeds. Monogastric animals are unable to digest phytic acid, making phytic acid phosphorous in animal waste one of the major causes of environmental phosphorus pollution.
( Song et al., 2022 )

SDN1
CRISPR/Cas

Dong-A University
Korea Research Institute of Bioscience Biotechnology (KRIBB), South Korea

Improved seed protein content.
( Shen et al., 2022 )

SDN1
CRISPR/Cas

Corteva Agriscience
University of Arizona, USA

Enhanced soybean aroma and functional marker for improving soybean flavor.
( Qian et al., 2022 )

SDN1
CRISPR/Cas

Zhejiang Academy of Agricultural Science
Ministry of Agriculture and Rural Affairs of China
Zhejiang University of Technology
Zhejiang Academy of Agricultural Sciences, China

Reduces phytic acid (anti-nutrient) and improves iron and zinc accumulation in wheat grains. Biofortification.
( Ibrahim et al., 2021 )

SDN1
CRISPR/Cas

Quaid-i-Azam University Islamabad
National Agricultural Research Centre, Pakistan

Altered protein composition due to mutations in seed storage proteins. Two major families of storage proteins, account for about 70% of total soy seed protein. Some major biochemical components influencing the quality of soy food products, for example tofu, are both the quantity and quality of storage proteins in soybean seeds.
( Li et al., 2019 )

SDN1
CRISPR/Cas

Agriculture and Agri-Food Canada
Western University
Harrow Research and Development Centre, Canada
Sun Yat-sen University
Guangdong Academy of Agricultural Sciences
Minnan Normal University
China

Promoted phenolic acid biosynthesis. Salvia is tradional Chinese medicine with great medical value to treat cardio- and cerebrovascular diseases. Phenolic acids make up a big part of the bioactive compounds.
( Shi et al., 2021 )

SDN1
CRISPR/Cas

East China University of Science and Technology
Zhejiang Chinese Medical University, China
University of Hawaii at Manoa, USA

Generation of seed lipoxygenase-free soybean. Lipoxygenases are responsible for an unpleasant beany flavor by the oxidation of unsaturated fatty acids, restricting human consumption.
( Wang et al., 2020 )

SDN1
CRISPR/Cas

Fujian Agriculture and Forestry University
Hebei Academy of Agricultural and Forestry Sciences, China

Increased soya bean isoflavone content and resistance to soya bean mosaic virus. Isoflavonoids play a critical role in plant-environment interactions and are beneficial to human health.
( Zhang et al., 2020 )

SDN1
CRISPR/Cas

Nanjing Agricultural University
Anhui Academy of Agricultural Science
Guangzhou University, China

High oleic, low linoleic and alpha-linolenic acid phenotype. High concentration of linoleic and alpha-linolenic acids causes oxidative instability.
( Do et al., 2019 )

SDN1
CRISPR/Cas

University of Missouri, USA
Vietnam Academy of Science and Technology, Vietnam

Reduced raffinose family oligosaccharide (RFO) levels in seeds. Human and other monogastric animals cannot digest major soluble carbohydrates, RFOs.
( Le et al., 2020 )

SDN1
CRISPR/Cas

Vietnam Academy of Science and Technology, Vietnam
University of Missouri, USA
Leibniz Institute of Plant Genetics and Crop Plant Research
Germany

High oleic acid, low linoleic content.
( al Amin et al., 2019 )

SDN1
CRISPR/Cas

Jilin Agricultural University, China

Low polyunsaturated fats content. Soybean oil is high in polyunsaturated fats and is often partially hydrogenated. The trans-fatty acids produced through hydrogenation pose a health threat.
( Haun et al., 2014 )

SDN1
TALENs

Cellectis plant sciences Inc., USA

High oleic and low linolenic oil to improve nutritional characteristics, increase shelf-life and frying stability.
( Demorest et al., 2016 )

SDN1
TALENs

Cellectis plant science Inc.
Calyxt, USA

Increased protein content and increased grain weight. Increase in grain protein content has a positive effect on flour protein content and gluten strength, two quality parameters.
( Zhang et al., 2018 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences
University of Chinese Academy of Sciences
Shandong Normal University, China

Reduced gluten content. Coeliac disease is an autoimmune disorder triggered in genetically predisposed individuals by the ingestion of gluten proteins.
( Sánchez-León,et al., 2017 )

SDN1
CRISPR/Cas

Instituto de Agricultura Sostenible (IASCSIC), Spain
University of Minnesota, USA

Modification of starch composition, structure and properties. Foods with a high amylose content (AC) and resistant starch (RS) offer potential to improve human health and lower the risk of serious non-infectious diseases.
( Li et al., 2020 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences (CAAS)
Nanjing Agricultural University, China

Increased iron (Fe) and magnesium (Mn) content for biofortification: increasing the intrinsic nutritional value of crops.
(Connorton et al., 2017)

SDN1
CRISPR/Cas

John Innes Centre
University of East Anglia, UK

Increased grain number per spikelet.
( Zhang et al., 2019 )

SDN1
CRISPR/Cas

University of Missouri
South Dakota State University
University of California
Donald Danforth Plant Science Center, USA
University of Bristol, UK

Reduce allergen proteins. Structural and metabolic proteins, like α-amylase/trypsin inhibitors are involved in the onset of wheat allergies (bakers' asthma) and probably Non-Coeliac Wheat Sensitivity (NCWS).
( Camerlengo et al., 2020 )

SDN1
CRISPR/Cas

University of Tuscia, Italy
Rothamsted Research, UK
Impasse Thérèse Bertrand-Fontaine, France

Reduced accumulation of free asparagine, the precursor for acrylamide. Acrylamide is a contaminant which forms during the baking, toasting and high-temperature processing of foods made from wheat.
( Raffan et al., 2021 )

SDN1
CRISPR/Cas

Rothamsted Research
University of Bristol, UK

Reduced amount of saturated fatty acids (FA) in soybean seeds for nutrititional improvement. FA are linked to cardiovascular diseases.
( Ma et al., 2021 )

SDN1
CRISPR/Cas

Zhejiang University, China
La Trobe University, Australia

High levels of monounsaturated fatty acids (MUFAs) in soybean seed oil. High MUFA content in vegetable oils can lead to significant health benefits and improve the oxidative stability, which are essential for both food usage and biodiesel (and other renewable resource) synthesis.
( Li et al., 2023 )

SDN1
CRISPR/Cas

Northeast Agricultural University, China

Reduced content of trypsin inhibitors, one of the most abundant anti-nutritional factors in soybean seeds. Reduction of trypsin inhibitors leads to improved. digestibility of soybean meal.
( Wang et al., 2023 )

SDN1
CRISPR/Cas

Virginia Tech, USA

Reduced levels of phytic acid (PA). PA has adverse effects on essential mineral absorption and thus is considered as an anti-nutritive for monogastric animals.
( Krishnan et al., 2023 )

SDN1
CRISPR/Cas

ICAR-Indian Agricultural Research Institute (IARI)
Bharathidasan University, India

Improved fatty acid content: high oleic acid, decreased linoleic acid content to improve nutritional characteristics, increase shelf-life and frying stability.
(Zhang et al., 2023)

SDN1
CRISPR/Cas

Jilin Agricultural University, China

Reduced content of anti-nutritional factors in soybean seeds, leading to improved digestibility.
( Figliano et al., 2023 )

SDN1
CRISPR/Cas

UEL - Universidade Estadual de Londrina, Portugal

Decreased storage-proteins, which allows improved forein protein production in seed.
( Ha et al., 2023 )

SDN1
CRISPR/Cas

Dong-A University
South Korea

β-conglycinin deficiency, which lowers allergenicity and increases nutritional value.
( Song et al., 2024 )

SDN1
CRISPR/Cas

Northeast Agricultural University/Key Laboratory of Soybean Biology of the Chinese Education Ministry
Harbin Normal University
Keshan Branch of Heilongjiang Academy of Agricultural Sciences
Jilin Agricultural University, China
USDA Agricultural Research Service
University of Missouri, USA

Traits related to increased plant yield and growth

Improved high-density yield and drought/osmotic stress tolerance.
( Chen et al., 2020 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Shanxi Academy of Agricultural Sciences, China
Texas Tech University, USA

Regulate shade avoidance. Soybean displays the classic shade avoidance syndrome (SAS), which leads to yield reduction and lodging under density farming conditions.
( Lyu et al., 2020 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Jilin Agricultural University
Shandong Agricultural University
Northeast Agricultural University, China

Increasing the number of seeds per pod (NSPP), an important yield determinant.
( Cai et al., 2021 )

SDN1
CRISPR/Cas

South China Agricultural University, China

Control flowering time, an important determinant for soybean yield and adaptation.
( Li et al., 2020 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences
University of Chinese Academy of Sciences
Guangzhou University
Agronomy College of Heilongjiang Bayi Agricultural University
Nanjing Agricultural University
Heilongjiang Academy of Agricultural Sciences, China

Late flowering. Photoperiod sensitivity limits geographical range of cultivation.
( Cai et al., 2017 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China

Altered spike architecture and grain treshability to increase grain production.
( Liu et al., 2020 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China

Bigger grains, increased grain weight.
( Zhang et al., 2018 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences, China

Enhanced photosynthesis and increases seed yield.
( Hu et al., 2022 )

SDN1
CRISPR/Cas

Nanjing Agricultural University
Chinese Academy of Sciences
Henan Institute of Science and Technology, China

Compact architecture with a smaller petiole angle than wild-type plants.
( Zhang et al., 2022 )

SDN1
CRISPR/Cas

Fujian Agriculture and Forestry University
Beijing Vocational College of Agriculture
Xiamen University, China

Altered plant architecture to inrease yield: increased node number on the main stem and branch number.
(Bao et al., 2019)

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Huazhong Agricultural University, China
Duy Tan University, Vietnam
RIKEN Center for Sustainable Resource Science, Japan

Increased nodule numbers. Soybean is a globally important crop for oil production and protein for human diet.
( Bai et al., 2019 )

SDN1
CRISPR/Cas

Fujian Agriculture and Forestry University
Nanchang University, China

Improvement for larger kernel and yield.
( Ma et al., 2015 )

SDN1
CRISPR/Cas

Northwest A &
F University
Chinese Academy of Agricultural Sciences, China

Increased spikelet number and delayed heading date. Two traits that are crucial and correlated to yield in wheat.
( Chen et al., 2022 )

SDN1
CRISPR/Cas

China Agricultural University, China

Increased yield potential trough improved nitrogen use efficiency. Enhanced tolerance to N starvation, and showed delayed senescence and increased grain yield in field conditions. Lowered use of N fertilizer.
( Zhang et al., 2021 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Zhengzhou University, China

Overexpression causes strongly promoted stem elongation, lower expression resulted in dwarf phenotype.
( Mu et al., 2022 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China

Increased grain weight and grain size. Carbohydrate and total protein levels also increased.
( Guo et al., 2021 )

SDN1
CRISPR/Cas

Sichuan Agricultural University, China
University of California, USA

Enhanced performance of soybean under dense conditions.
( Ji et al., 2022 )

SDN1
CRISPR/Cas

Academy of Agricultural Sciences
Southern University of Science and Technology, China

Promoting nodulation: up-regulation of expression levels of genes involved in nodulation. Nitrogen-fixing symbiotic nodules strongly up regulate yield.
(Wang et al., 2022)

SDN1
CRISPR/Cas

Beijing Institute of Technology
Chinese Academy of Agricultural Sciences, China

Increased yield: plants produced more tillers and grains than azygous wild-type controls and the total yield was increased up to 15 per cent.
(Holubova et al., 2018)

SDN1
CRISPR/Cas

Palacký University
Centre of the Region Haná for Biotechnological and Agricultural Research, Czech Republic
Leibniz Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben, Germany

Improved pod shattering resistance. Pod shattering has been a negatively selected trait in soybean domestication and breeding as it can lead to devastating yield loss of soybean.
( Zhang et al., 2022 )

SDN1
CRISPR/Cas

Fujian Agriculture and Forestry University
Heilongjiang Bayi Agricultural University
Hebei Academy of Agricultural and Forestry Sciences, China

Reduction of soybean plant height and shortening of the internodes. The height of the soybean plant is a key trait that significantly impacts the yield.
( Cheng et al., 2019 )

SDN1
CRISPR/Cas

Guangzhou University
Chinese Academy of Sciences
University of Chinese Academy of Sciences, China

Control flowering time, an important determinant for soybean yield and adaptation.
( Wang et al., 2023 )

SDN1
CRISPR/Cas

Guangzhou University
Yunnan Agricultural University
Nanjing Agricultural University
Key Laboratory of Crop Genetics and Breeding of Hebei, China

Increase in 1000-grain weight, grain area, grain width, grain length, plant height, and spikelets per spike.
( Errum et al., 2023 )

SDN1
CRISPR/Cas

National Agricultural Research Centre (NARC)
PARC Institute of Advanced Studies in Agriculture (PIASA)
Pakistan Agricultural Research Council, Pakistan

Altered plant architecture to increase yield: more compact plant architecture.
(Kong et al., 2023)

SDN1
CRISPR/Cas

Nanjing Agricultural University
Chinese Academy of Agricultural Sciences
Hebei Academy of Agricultural and Forestry Sciences, China

Early heading. Heading date is an important agronomic trait that affects climatic adaptation and yield potential.
( Fan et al., 2023 )

SDN1
CRISPR/Cas

Henan Agricultural University, China

Enhanced grain yield and semi-dwarf phenotype by manipulating brassinosteroid signal pathway.
( Song et al., 2023 )

SDN1
CRISPR/Cas

China Agricultural University, China
Hard Winter Wheat Genetics Research Unit, USA

Shorter flowering time and increased yield.
( Cheng et al., 2023 )

SDN1
CRISPR/Cas

Jilin Normal University
Jilin Academy of Agricultural Sciences, China

Altered root architecture with increased tillers and total grain weight.
( Rahim et al., 2023 )

SDN1
CRISPR/Cas

Quaid-e-Azam University
National Agricultural Research Centre (NARC)
The University of Haripur, Pakistan
King Saud University, Saudi Arabia
Nile University
Ain Shams University, Egypt
Chonnam National University, South Korea

Shortened flowering time and maturity, determining their favourable latitudinal zone for cultivation.
( Gao et al., 2024 )

SDN1
CRISPR/Cas

Syngenta Seed Technology China Co., China

Bigger seeds and increased yield.
( Xie et al., 2024 )

SDN1
CRISPR/Cas

Anhui Agricultural University
Anhui Agricultural University
Bellagen Biotechnology Co. Ltd
Ministry of Agriculture and Rural Affairs
Southern University of Science and Technology
Hainan Yazhou Bay Seed Laboratory, China

Dwarf phenotype, which can aid in obtaining more compact, densely planted soybean varieties to boost productivity.
( Xiang et al., 2024 )

SDN1
CRISPR/Cas

Wuhan Polytechnic University
Chinese Academy of Agricultural Sciences, China

Increased seed size and yields without alterations in plant architecture or seed nutrition.
( Wang et al., 2024 )

SDN1
CRISPR/Cas

Northeast Forestry University
Northeast Agricultural University, China

Increased plant height with an earlier heading date.
( Fu et al., 2024 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Henan Normal University
Sichuan Agricultural University
Henan Agricultural University
Shanxi University, China

Earlier maturation time under both short-day and long-day conditions.
( Wu et al., 2024 )

SDN1
CRISPR/Cas

Heilongjiang Bayi Agricultural University
Chinese Academy of Agricultural Sciences
Northeast Agricultural University
Syngenta Biotechnology (China) Co. Ltd, China

Increased grain yield.
( Chen et al., 2024 )

SDN1
CRISPR/Cas

Increased tiller number.
( Awan et al., 2024 )

SDN1
CRISPR/Cas

National Institute for Biotechnology and Genetic Engineering
Quaid-i-Azam University, Pakistan

Traits related to industrial utilization

Significantly longer seed dormancy period, may result in reduced pre-harvest sprouting of grains on spikes.
( Abe et al., 2019 )

SDN1
CRISPR/Cas

Institute of Crop Science
Okayama University
Yokohama City University
Institute of Agrobiological Sciences
Obihiro University of Agriculture and Veterinary Medicine, Japan

New red-grained and pre-harvest sprouting (PHS)-resistant wheat varieties with elite agronomic traits. PHS reduces yield and grain quality, additionally the red pigment of the grain coat contains proanthocyanidins, which have antioxidant activity and thus health-promoting properties.
( Zhu et al., 2022 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Fujian Academy of Agricultural Sciences
Henan University
Shenzhen Research Institute of Henan university
Taiyuan University of Technology
Southern University of Science and Technology, China
University of Edinburgh, UK

Generating male sterility lines (MLS). Using MLS in hybrid seed production reduces costs and ensures high purity of the varieties because it does not produce pollen and has exserted stigmas.
( Zhang et al., 2023 )

SDN1
CRISPR/Cas

Shandong Academy of Agricultural Sciences
Key Laboratory of Wheat Biology and Genetic Improvement on North Yellow and Huai River Valley
National Engineering Laboratory for Wheat and Maize
Chinese Academy of Agricultural Sciences, China

Generation of male sterility lines. Heterosis, the breeding result in which heterozygous hybrid progeny are superior to both homozygous parents, depends on the selection and application of male-sterile lines (MSL). Using MSL can reduce the production cost of hybrid seeds and improve its quality.
( Chen et al., 2021 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences
University of Chinese Academy of Sciences
Jilin Agricultural University
Jilin Academy of Agricultural Sciences, China

Control photoperiodic flowering to allow adaptation of cultivars. Flowering time is a critical characteristic to determine the geographic distribution and regional adaptability of soybean.
( Wang et al., 2020 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China

Rapid generation of male sterile (MS) bread wheat. MS is an important tool in creating hybrid crop varieties that provide a yield advantage over traditional varieties by harnessing heterosis.
( Singh et al., 2021 )

SDN1
CRISPR/Cas

DuPont Pioneer, USA

SDN1
CRISPR/Cas

Peking University Institute of Advanced Agricultural Sciences
Peking University
Beijing Key Laboratory of Plant Gene Resources and Biotechnology for Carbon Reduction and Environmental Improvement, China

Fertility recovery of male sterility in wheat lines with excelling agronomic and economic traits for breeding purpose, as male-sterile plants cannot be used for selection.
( Tang et al., 2021 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
China Agricultural University, China

Manipulation of the biosynthesis of bioactive compound alkaloids. Poppy produces many benzylisoquinoline alkaloids (BIAs) used in biomedicines.
( Alagoz et al., 2016 )

SDN1
CRISPR/Cas

Cankiri Karatekin University
Dokuz Eylul University, Turkey

Generation of male-sterile hexaploid wheat lines for use in hybrid seed production. The development and adoption of hybrid seed technology have led to dramatic increases in agricultural productivity.
( Okada et al., 2019 )

SDN1
CRISPR/Cas

The University of Adelaide, Australia
Huaiyin Normal University, China

Complete male sterility. The generation, restoration, and maintenance of male sterile lines are the key issues for large-scale commercial hybrid seed production.
( Li et al., 2020 )

SDN1
CRISPR/Cas

Peking University Institute of Advanced Agricultural Sciences
School of Advanced Agriculture Sciences and School of Life Sciences
Beijing Key Laboratory of Plant Gene Resources and Biotechnology for Carbon Reduction and Environmental Improvement, China

Confer male and female sterility to prevent the risk of trasgene flow from transgenic plants to their wild relatives.
( Wu et al., 2024 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences
University of Chinese Academy of Sciences
Jilin Agricultural University
Zhejiang Lab, China

Traits related to herbicide tolerance

Herbicide glyphosate tolerance.
( Arndell et al., 2019 )

SDN1
CRISPR/Cas

CSIRO
New South Wales Department of Primary Industries
The University of Adelaide, Australia

Nicosulfuron
( Zong et al., 2018 )

Chinese Academy of Sciences, China

Chlorsulfuron
( Li et al., 2015 )

SDN2
CRISPR/Cas

DuPont Pioneer Agricultural Biotechnology, USA

Nicosulfuron, mesosulfuron, imazapic, quizalofop
( Zhang et al., 2019 )

Chinese Academy of Sciences
China Agricultural University, China

Dinitroanaline
( Han et al., 2021 )

Shandong Normal University
Shandong Academy of Agricultural Sciences, China

Herbicide tolerance: resistance to AHAS-inhibiting herbicides.
(Wei et al., 2023)

Nankai University
China Agricultural University, China

Traits related to product color/flavour

Albino phenotype and early flowering.
( Charrier et al., 2019 )

SDN1
CRISPR/Cas

Université d'
Angers, France

Brown seed-coat color.
( Jia et al., 2020 )

SDN1
CRISPR/Cas

Southern University of Science and Technology
Chinese Academy of Agricultural Sciences
South China Agricultural University, China
Donald Danforth Plant Science Center
University of Missouri, USA

Traits categories

Genome Editing Technique

Countries

Plant

Sdn Type

Traits related to biotic stress tolerance

Traits related to abiotic stress tolerance

Traits related to improved food/feed quality

Traits related to increased plant yield and growth

Traits related to industrial utilization

Traits related to herbicide tolerance

Traits related to product color/flavour