genome search | EU-SAGE

Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 18 results

Traits related to industrial utilization

Reduced lignin content and increased sugar release upon saccharification.
( De Meester et al., 2021 )

SDN1
CRISPR/Cas

Ghent University
VIB Center for Plant Systems Biology, Belgium

Generating male sterility lines (MLS). Using MLS in hybrid seed production reduces costs and ensures high purity of the varieties because it does not produce pollen and has exserted stigmas.
( Jung et al., 2020 )

SDN1
CRISPR/Cas

Hankyong National University
Hanyang University
Sunchon National University
Chungbuk National University
Tomato Research Center, South Korea

Doubled haploids with increased leaf size. Doubled haploid technology is used to obtain homozygous lines in a single generation. This technique significantly accelerates the crop breeding trajectory.
( Impens et al., 2023 )

SDN1
CRISPR/Cas

Ghent University
VIB-UGent Center for Plant Systems Biology
Flanders Research Institute for Agriculture, Fisheries and Food (ILVO), Belgium

Male sterility: mutants did not produce pollen and induced a parthenocarpic fruit set.
(Gökdemir et al., 2022)

SDN1
CRISPR/Cas

Ondokuz Mayıs University
Burdur Mehmet Akif Ersoy University, Turkey

35% reduction in lignin. Fourfold increase in cellulose-to-glucose conversion upon limited saccharification. Efficient saccharification is hindered by the presence of lignin in the secondary-thickened cell walls.
( de Vries et al., 2021 )

SDN1
CRISPR/Cas

Ghent University
VIB Center for Plant Systems Biology, Belgium

Bio-fuel production: Reduced lignin content, improves cell wall composition for production of bio-ethanol.
(Jung et al., 2016)

SDN1
TALENs

Korea University, South Korea
University of Florida, USA

Glycoproteins without plant-specific glycans. Plants or plant cells can be used to produce pharmacological glycoproteins, for example antibodies or vaccines. However these proteins carry N-glycans with plant-typical residues [β(1,2)-xylose and core α(1,3)-fucose]. This plant-specific glycans can greatly impact the immunogenicity, allergenicity, or activity of the protein.
( Mercx et al., 2017 )

SDN1
CRISPR/Cas

Université catholique de Louvain
Université de Liège, Belgium

Higher haploid induction rate. Haploid induction allows formation of doubled haploids, which can be used to rapidly fix genetic information.
( Jang et al., 2023 )

SDN1
CRISPR/Cas

Chonnam National University
Pusan National University
Kyung Hee University, South Korea

Delayed flowering time.
( Hong et al., 2021 )

SDN1
CRISPR/Cas

National Institute of Agricultural Sciences, South Korea

Smaller petunia plants with high flower abundance.
( Abdulla et al., 2024 )

SDN1
CRISPR/Cas

Ondokuz Mayis University, Turkey
Agricultural Research Center (ARC), Egypt

Jointless tomatoes. Pedicel abscission is an important agronomic factor that controls yield and post-harvest fruit quality. In tomato, floral stems that remain attached to harvested fruits during picking mechanically damage the fruits during transportation, decreasing the fruit quality for fresh-market tomatoes and the pulp quality for processing tomatoes.
( Roldan et al., 2017 )

SDN1
CRISPR/Cas

Institute of Plant Sciences Paris-Saclay (IPS2), France
University of Liège, Belgium

Increased monounsaturated fatty acid contents (MUFAs). Due to their higher thermal-oxidative stability and viscosity relative to other common fatty acids, MUFAs are preferred for industrial uses, for example as biolubricants and biodiesel fuels.
( Lee et al., 2021 )

SDN1
CRISPR/Cas

National Institute of Agricultural Sciences
Korea Advanced Institute of Science and Technology
Chonnam National University
Plant Engineering Research Institute, South Korea

Early-flowering.
( Jeong et al., 2021 )

SDN1
CRISPR/Cas

Department of Biological Science
Seoul National University
Chungnam National University
Institute for Basic Science
Kangwon National University
Kyunghee University, South Korea

Manipulation of the biosynthesis of bioactive compound alkaloids. Poppy produces many benzylisoquinoline alkaloids (BIAs) used in biomedicines.
( Alagoz et al., 2016 )

SDN1
CRISPR/Cas

Cankiri Karatekin University
Dokuz Eylul University, Turkey

Tailoring poplar lignin without yield penalty. Reduced recalcitrance.
( De Meester et al., 2020 )

SDN1
CRISPR/Cas

Ghent University
VIB Center for Plant Systems Biology
VIB Metabolomics Core, Belgium

Improve biofuel production by mediating lignin modification. Lignocellulosic biomasses are an abundant renewable source of carbon energy. Heterogenous properties of lignocellulosic biomass and intrinsic recalcitrance caused by cell wall lignification lower the biorefinery efficiency. Reduced lignin content is desired.
( Lee et al., 2021 )

SDN1
CRISPR/Cas

Korea Institute of Science and Technology (KIST)
University of Science and Technology (UST)
Daejeon, South Korea

Bioethanol production: Improved saccharification efficiency without compromising biomass yield.
(Kannan et al., 2017)

SDN1
TALENs

University of Florida
Novozymes North America Inc, USA
Korea Institute of Science and Technology (KIST), South Korea

Generating male sterility lines (MLS) and enhanced tolerance against drought stress. Using MLS in hybrid seed production reduces costs and ensures high purity of the varieties because it does not produce pollen and has exserted stigmas.
( Secgin et al., 2022 )

SDN1
CRISPR/Cas

Ondokuz Mayıs University
Burdur Mehmet Akif Ersoy University
Ondokuz Mayıs University, Turkey
Agricultural Research Center (ARC), Egypt

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Traits related to industrial utilization