Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Sdn Type

Displaying 28 results

Traits related to biotic stress tolerance

Viral resistance: increased resistance to infection with the potato virus Y (PVY) and tolerance to salt and osmotic stress. PVY is one of the most economically important potato pathogens
(Makhotenko et al., 2019)
SDN1
CRISPR/Cas
Russia Moscow State University, Russia
Doka Gene Technologies Ltd, USA
Resistance against a protist pathogen: stable resistance against clubroot disease. Clubroot disease is caused by the protist Plasmodiophora brassicae Woronin and can result in a 10-15% yield loss in Brassica species as well as related crops.
(Hu et al., 2023)
SDN1
CRISPR/Cas
Saskatoon Research and Development Centre, Canada
Bacterial resistance: Resistance to Pseudomonas syringae DC3000, a widespread pathogen that causes bacterial speck disease of tomato.
(Ortigosa et al., 2019)
SDN1
CRISPR/Cas
Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CNB-CSIC),Spain

Fungal resistance: resistance to Fusarium graminearum. Fusarium head blight (FHB) is an economically important disease, affecting both yield and grain quality of maize, wheat and barley.
(Brauer et al., 2020)
SDN1
CRISPR/Cas
Ottawa Research and Development Centre, Canada
Fungal resistance: increased resistance to Phytophthora infestans, causing late blight disease, the most serious disease of potato crops worldwide. The pathogen can infect the leaves, stems and tubers of potato plants. An unprotected field can be completely destroyed in several days.
(Kieu et al., 2021)
SDN1
CRISPR/Cas
Swedish University of Agricultural Sciences, Sweden
University of Copenhagen, Denmark

Traits related to abiotic stress tolerance

Increased tolerance to drought trough reducing water loss. Tuber development.
( Gonzales et al., 2020 )
SDN1
CRISPR/Cas
Wageningen University and Research, The Netherlands
Centro Nacional de Biotecnología – CSIC
Universidad Politécnica de Madrid (UPM), Spain
Reduced cuticle permeability and enhanced drought tolerance.
( He et al., 2022 )
SDN1
CRISPR/Cas
Northwest A&
F University
USA
University of British Columbia, Canada
Increased root length, which can restore good performance under water stress.
( Gabay et al., 2023 )
SDN1
CRISPR/Cas
University of California
Howard Hughes Medical Institute, USA
University of Haifa, Israel
Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET)
Universidad Nacional de San Martín (UNSAM), Argentina
Fudan University
China Agricultural University, China
Karolinska Institutet, Sweden

Traits related to improved food/feed quality

Reduced gluten content. Coeliac disease is an autoimmune disorder triggered in genetically predisposed individuals by the ingestion of gluten proteins.
( Sánchez-León,et al., 2017 )
SDN1
CRISPR/Cas
Instituto de Agricultura Sostenible (IASCSIC), Spain
University of Minnesota, USA
Production of opaque seeds with depleted starch reserves. Reduced starch content and increased amylose content. Accumulation of multiple sugars, fatty acids, amino acids and phytosterols.
( Baysal et al., 2020 )
SDN1
CRISPR/Cas
University of Lleida-Agrotecnio Center
Catalan Institute for Research and Advanced Studies (ICREA), Spain
Royal Holloway University of London, UK
Improved digestibility of kafirins, which increases the grain nutritional value.
( Elkonin et al., 2023 )
SDN1
CRISPR/Cas
Federal Centre of Agriculture Research of South-East Region
Institute of Biochemistry and Genetics, Russia
Altered protein composition due to mutations in seed storage proteins. Two major families of storage proteins, account for about 70% of total soy seed protein. Some major biochemical components influencing the quality of soy food products, for example tofu, are both the quantity and quality of storage proteins in soybean seeds.
( Li et al., 2019 )
SDN1
CRISPR/Cas
Agriculture and Agri-Food Canada
Western University
Harrow Research and Development Centre, Canada
Sun Yat-sen University
Guangdong Academy of Agricultural Sciences
Minnan Normal University
China
Starch with an increased amylose ratio and elongated amylopectin chains. In food products, high amylose content and long amylopectin chains contribute to a low glycaemic index (GI) after intake, playing a role in health benefits.
( Zhao et al., 2021 )
SDN1
CRISPR/Cas
Swedish University of Agricultural Sciences, Sweden
Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET)
Laboratorio de Agrobiotecnología (INTA), Argentina
Improved kafirin digestibility, which increases the grain nutritional value.
( Elkonin et al., 2023 )
SDN1
CRISPR/Cas
Federal Centre of Agriculture Research of South-East Region
Institute of Biochemistry and Genetics – Subdivision of the Ufa Federal Research Centre of the Russian Academy of Sciences, Russia
Improved starch quality. Starch has many food and technical applications and is often modified to certain specifications.
( Andersson et al., 2017 )
SDN1
CRISPR/Cas
Swedish University of Agricultural Sciences, Sweden
Improved seed oil content: increased levels of monounsaturated fatty acids and decreased levels of polyunsaturated fatty acids.
(Wang et al., 2022)
SDN1
CRISPR/Cas
Huazhong Agricultural University, China
National Research Council Canada, Canada
Glossy sheat phenotype.
( Gerasimova et al., 2023 )
SDN1
CRISPR/Cas
Siberian Branch of the Russian Academy of Sciences
Vavilov Institute of Plant Genetic Resources (VIR)
Siberian Branch of the Russian Academy of Sciences, Russia

Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Germany

Traits related to increased plant yield and growth

Confer shoot architectural changes for increased resource inputs to increase crop yield.
( Stanic et al., 2021 )
SDN1
CRISPR/Cas
University of Calgary, Canada
SRM Institute of Technology, India

Traits related to industrial utilization

Parthenocarpy: seedless tomatoes
(Nieves-Cordones et al., 2020)
SDN1
CRISPR/Cas
Centro de Edafología y Biología Aplicada del Segura-CSIC, Spain
Confer male and female sterility to prevent the risk of trasgene flow from transgenic plants to their wild relatives.
( Shinoyama et al., 2020 )
SDN1
TALENs
Fukui Agricultural Experiment Station
Institute of Agrobiological Sciences
National Agriculture and Food Research Organization (NARO)
Japan Science and Technology Agency (JST)
Yokohama City University, Japan
Altai State University, Russia

Traits related to herbicide tolerance

Bispyribac sodium
( Kuang et al., 2020 )

BE
Chinese Academy of Agricultural Sciences
China Agricultural University
Zhejiang University, China
Norwegian Institute of Bioeconomy Research, Norway
Dinitroanaline
( Liu et al., 2021 )

BE
Chinese Academy of Agricultural Sciences
China Agricultural University
Zhejiang University
Scientific Observing and Experimental Station of Crop Pests in Guilin, Ministry of Agriculture and Rural Affairs, China
Norwegian Institute of Bioeconomy Research, Norway
Herbicide tolerance: AHAS-inhibiting
(Gocal et al., 2015)

ODM
Cibus, Canada
Cibus, USA

Traits related to product color/flavour

Improved aroma, flavour and fatty acid (FA) profiles of pea seeds.
( Bhowmik et al., 2023 )
SDN1
CRISPR/Cas
National Research Council Canada (NRC)
University of Calgary
University of Saskatchewan
Agriculture and Agri-Food Canada (AAFC)
St. Boniface Hospital Research, Canada
John Innes Centre, UK
A significant reduction of saponins. Saponins are a source of bitter, and metallic off-flavors in products containing peas.
( Hodgins et al., 2024 )
SDN1
CRISPR/Cas
Universityof Calgary
Universityof Saskatchewan
National Research Council of Canada, Canada

Traits related to storage performance

Reduced enzymatic browning. The formation of dark-colored precipitates in fruits and vegetables causes undesirable changes in organoleptic properties and the loss of nutritional quality.
( Gonzalez et al., 2020 )
SDN1
CRISPR/Cas
Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET)
Laboratorio de Agrobiotecnología (INTA)
Universidad Nacional de Mar del Plata, Argentina
Swedish University of Agricultural Sciences, Sweden
Improved strawberry fruit firmness. The postharvest shelf life is highly limited by the loss of firmness, making firmness one of the most important fruit quality traits.
( López-Casado et al., 2023 )
SDN1
CRISPR/Cas
Universidad de Málaga
Universidad de Córdoba, Spain
Reduced fruit flesh browning. The browning of eggplant berry flesh after cutting has a negative impact on fruit quality for both industrial transformation and fresh consumption.
( Maioli et al., 2020 )
SDN1
CRISPR/Cas
University of Torino, Italy
Instituto de Biologica Molecular y Celular de Plantas (IBMCP)
Universitat Politècnica de València, Spain