Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Genome Editing Technique

Displaying 24 results

Traits related to biotic stress tolerance

Significantly enhanced resistance to V. dahliae, and furthermore also to Verticillium albo-atrum and Fusarium oxysporum f. sp. lycopersici (Fol), despite severe growth defects.
( Hanika et al., 2021 )
SDN1
CRISPR/Cas
Wageningen University &
Research, The Netherlands
Fungal resistance: Reduced susceptibility to necrotrophic fungi. Necrotrophic fungi, such as Botrytis cinerea and Alternaria solani, cause severe damage in tomato production.
(Ramirez Gaona et al., 2023)
SDN1
CRISPR/Cas
Wageningen University &
Research, The Netherlands
Takii &
Company Limited, Japan
Fungal resistance: Enhanced resistance against powdery mildew, caused by Oidium neolycopersici, which is a major concern for the productivity of tomato plants.
(Li et al., 2024)
SDN1
CRISPR/Cas
University of Torino, Italy
Wageningen University &
Research, The Netherlands
Shanxi Agricultural University, China
Fungal resistance: effective reduction of susceptibility against downy mildew by increasing salicylic acid levels. The pathogen can devastate individual vineyards and in some cases also affect production from entire regions.
(Giacomelli et al., 2023)
SDN1
CRISPR/Cas
Research and Innovation Centre
Fondazione Edmund Mach, Italy
Enza Zaden
Hudson River Biotechnology, The Netherlands
Fungal resistance: increased resistance against the fungus Pyricularia oryzae, causing rice blast, one of the most destructive diseases affecting rice worldwide.
(Távora et al., 2022)
SDN1
CRISPR/Cas
Federal University of Juiz de Fora
Embrapa Genetic Resources and Biotechnology
Catholic University of Brasilia
Catholic University of Dom Bosco, Brazil
Agricultural Research Center for International Development (CIRAD)
University of Montpellier
Montpellier SupAgro, France
Fungal resistance: Resistance against the blast fungus Mangaporthe oryzae.
(Bundó et al., 2024)
SDN1
CRISPR/Cas
Campus Universitat Autònoma de Barcelona (UAB)
Consejo Superior de Investigaciones Científcas (CSIC), Spain
Academia Sinica No 128, Taiwan
Fungal resistance: Reduced susceptibility to the powdery mildew pathogen (Oidium neolycopersici), a world-wide disease threatening the production of greenhouse- and field-grown tomatoes.
(Santillán Martínez et al., 2020)
SDN1
CRISPR/Cas
Wageningen University &
Research, The Netherlands
Fungal resistance: increased resistance against powdery mildew, a destructive disease that threatens cucumber production globally.
(Dong et al., 2023)
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences, China
University of California Davis, USA
Wageningen University &
Research, The Netherlands

Traits related to abiotic stress tolerance

Higher tolerance to salt and osmotic stress through reduced stomatal conductance coupled with increased leaf relative water content and Abscisic acid (ABA) content under normal and stressful conditions.
( Bouzroud et al., 2020 )
SDN1
CRISPR/Cas
Université Mohammed V de Rabat, Morocco
Université de Toulouse, France
Universidade Federal de Viçosa, Brazil
Increased drought-avoidance strategy.
( Maioli et al., 2024 )
SDN1
CRISPR/Cas
University of Torino, Italy
Ingeniero Fausto Elio/n, Spain
Wageningen University &
Research, The Netherlands
Increased tolerance to drought trough reducing water loss. Tuber development.
( Gonzales et al., 2020 )
SDN1
CRISPR/Cas
Wageningen University and Research, The Netherlands
Centro Nacional de Biotecnología – CSIC
Universidad Politécnica de Madrid (UPM), Spain
Improved salinity tolerance.
( Wang et al., 2022 )
SDN1
CRISPR/Cas
National Taiwan University, Taiwan
University of North Carolina, USA

Traits related to improved food/feed quality

Production of high amylose and resistant starch rice. Starch accounts for 80 to 90% of the total mass of rice seeds and is low in resistant starch (RS), which is beneficial in preventing various diseases. Starch with high amylose content (AC) and RS have a lower GI value. Foods with low GI value have beneficial effects on glycemic control.
( Wang et al., 2021 )
SDN1
CRISPR/Cas
National Chiayi University
Taiwan Agricultural Research Institute Chiayi Agricultural Experiment Branch, Taiwan

Traits related to increased plant yield and growth

Reduced seed shattering. Seed shattering is one of the main constraints on grain production in African cultivated rice, which causes severe grain losses during harvest.
( Ning et al., 2023 )
SDN1
CRISPR/Cas
China Agricultural University, China
Africa Rice Center, Benin
Altered spike architecture.
( de Souza Moraes et al., 2022 )
SDN1
CRISPR/Cas
Wageningen University and Research, The Netherlands
Universidade de São Paulo, Brazil
Norwich Research Park, UK
Rheinische Friedrich-Wilhelms-Universität, Germany
Increased total kernel number or kernel weight.
( Kelliher et al., 2019 )
SDN1
CRISPR/Cas
Research Triangle Park
University of Georgia, USA
Syngenta Crop Protection, The Netherlands
Combine agronomically desirable traits with useful traits present in wild lines. Threefold increase in fruit size and a tenfold increase in fruit number. Fruit lycopene accumulation is improved by 500% compared with the widely cultivated S. lycopersicum.
( Zsögön et al., 2018 )
SDN1
CRISPR/Cas
Universidade Federal de Viçosa
Universidade de São Paulo Paulo, Brazil
University of Minnesota, USA
Universität Münster, Germany

Traits related to industrial utilization

Increasing cross over frequency. Cross over formation during meiosis is essential for crop breeding to introduce favourable alleles controlling important traits from wild relatives into crops.
( de Maagd et al., 2020 )
SDN1
CRISPR/Cas
Wageningen University &
Research, The Netherlands
Generate self-compatible diploid potato lines for the application of efficient breeding methods.
( Eggers et al., 2021 )
SDN3
CRISPR/Cas
Solynta
Wageningen University &
Research, The Netherlands
Conversion of hulled into naked barley.
( Gasparis et al., 2018 )
SDN1
CRISPR/Cas
National Research Institute
Warsaw University of Life Sciences (SGGW), Poland
Establishment of maternal haploid induction. Doubled haploid technology is used to obtain homozygous lines in a single generation. This technique significantly accelerates the crop breeding trajectory.
( Zhong et al., 2022 )
SDN1
CRISPR/Cas
China Agricultural University, China
Wageningen University and Research, The Netherlands
Establishment of maternal haploid induction. Doubled haploid technology is used to obtain homozygous lines in a single generation. This technique significantly accelerates the crop breeding trajectory.
( Zhong et al., 2022 )
SDN1
CRISPR/Cas
China Agricultural University, China
Wageningen University and Research, The Netherlands

Traits related to product color/flavour

Colour shift. The poinsettia belongs to most economically important potted ornamental plants. Customers are willing to pay higher prices for unusual varieties.
( Nitarska et al., 2021 )
SDN1
CRISPR/Cas
Technische Universität Wien, Austria
Klemm+Sohn GmbH &
Co
Leibniz Universität Hannover, Germany
Color modification due to reduced anthocyanin accumulation.
( Klimek-Chodacka et al., 2018 )
SDN1
CRISPR/Cas
University of Agriculture in Krakow, Poland
East Carolina University
University of Maryland, USA