genome search | EU-SAGE

Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 27 results

Traits related to biotic stress tolerance

Nematode resistance: decreased susceptibility against root-knot nematodes, showing fewer gall and egg masses.
(Noureddine et al., 2023)

SDN1
CRISPR/Cas

Université Côte d’Azur
Université de Toulouse, France
Kumamoto University, Japan

Viral and fungal resistance: Tomato yellow leaf curl virus (TYLCV) and powdery mildew (Oidium neolycopersici), diseases which reduce tomato crop yields and cause substantial economic losses each year.
(Pramanik et al., 2021)

SDN1
CRISPR/Cas

Gyeongsang National University
Pusan National University
R&
D Center, Bunongseed Co., South Korea

Fungal and bacterial resistance: increased resistance towards the bacterial pathogen Pseudomonas syringae pv. maculicola (Psm) and fungal pathogen Alternaria brassicicola.
(Yung Cha et al., 2023)

SDN1
CRISPR/Cas

Gyeongsang National University, South Korea

Herbicide resistance: pds (phytoene desaturase), ALS (acetolactate synthase), and EPSPS (5-Enolpyruvylshikimate-3-phosphate synthase)
(Yang et al., 2022)

SDN1
CRISPR/Cas

Chonnam National University, South Korea

Viral resistance: Resistance to Tomato brown rugose fruit virus (ToBRFV), a major threat to the production of tomato.
(Ishikawa et al., 2022)

SDN1
CRISPR/Cas

Institute of Agrobiological Sciences
Takii and Company Limited, Japan

Fungal resistance: Reduced susceptibility to necrotrophic fungi. Necrotrophic fungi, such as Botrytis cinerea and Alternaria solani, cause severe damage in tomato production.
(Ramirez Gaona et al., 2023)

SDN1
CRISPR/Cas

Wageningen University &
Research, The Netherlands
Takii &
Company Limited, Japan

Viral resistance: resistance to pepper mottle virus (PepMoV), causing considerable damage to crop plants.
(Yoon et al., 2020)

SDN1
CRISPR/Cas

Seoul National University
National Institute of Horticultural and Herbal Science, South Korea

Traits related to abiotic stress tolerance

Tolerance to salt stress.
( Tran et al., 2021 )

SDN1
CRISPR/Cas

Gyeongsang National University, South Korea
College of Agriculture
Bac Lieu University, Vietnam

Traits related to improved food/feed quality

Increased sugar content without decreased fruit weight. Sugar content is one of the most important quality traits of tomato.
( Kawaguchi et al., 2021 )

SDN1
CRISPR/Cas

Nagoya University
Kobe University
RIKEN Center for Sustainable Resource Science
University of Tsukuba, Japan

Increased gamma-Aminobutyric acid (GABA) accumulation by 7 to 15 fold while having variable effects on plant and fruit size and yield. GABA is a nonproteogenic amino acid and has health-promoting functions.
( Nonaka et al., 2017 )

SDN1
CRISPR/Cas

University of Tsukuba, Japan

Increased carotenoid, lycopene, and β-carotene.
( Hunziker et al., 2020 )

University of Tsukuba
Kobe University
Institute of Vegetable and Floricultural Science
NARO, Japan

Seedless tomatoes for industrial purposes and direct eating quality.
( Ueta et al., 2017 )

SDN1
CRISPR/Cas

Tokushima University, Japan

Important metabolic changes affecting tomato fruit quality. Reduced contents of the anti-nutrient oxalic acid.
( Gago et al., 2017 )

SDN1
ZFN

University of Algarve, Portugal
Centre for Research and Technology Hellas
Technological Educational Institution of Crete, Greece

Improvement of of functional compounds in tomato fruit, which satisfies the antioxidant properties requirements.
( Kim et al., 2024 )

SDN1
CRISPR/Cas

Hankyong National University
Chungbuk National University, South Korea

Traits related to increased plant yield and growth

Customize tomato cultivars for urban agriculture: increased compactness and decreased growth cycle of tomato plants.
(Kwon et al., 2020)

SDN1
CRISPR/Cas

Cold Spring Harbor Laboratory
Cornell University
University of Florida, USA
Wonkwang University, South Korea
Weizmann Institute of Science, Israel

Regulating fruit ripening, one of the most important concerns in the study of fleshy fruit species.
( Ito et al., 2015 )

SDN1
CRISPR/Cas

National Food Research Institute, Japan

Elongated, occasionally peanut-like shaped fruit.
( Zheng et al., 2022 )

SDN1
CRISPR/Cas

Nagoya University
Kanazawa University, Japan
Huazhong Agricultural University, China

Enhanced sink strength in tomato, improving fruit setting, and yield contents.
( Nam et al., 2022 )

SDN1
CRISPR/Cas

Pohang University of Science and Technology
Wonkwang University, South Korea

Optimum increase in phloem-transportation capacity leads to improved sink strength in tomato to increase agricultural crop production.
( Nam et al., 2022 )

SDN1
CRISPR/Cas

Pohang University of Science and Technology
Wonkwang University, South Korea

Traits related to industrial utilization

Generating male sterility lines (MLS) and enhanced tolerance against drought stress. Using MLS in hybrid seed production reduces costs and ensures high purity of the varieties because it does not produce pollen and has exserted stigmas.
( Secgin et al., 2022 )

SDN1
CRISPR/Cas

Ondokuz Mayıs University
Burdur Mehmet Akif Ersoy University
Ondokuz Mayıs University, Turkey
Agricultural Research Center (ARC), Egypt

Dwarf plants that retain favourable fruit traits.
( Nagamine et al., 2024 )

SDN1
CRISPR/Cas

University of Tsukuba, Japan

Male sterility: mutants did not produce pollen and induced a parthenocarpic fruit set.
(Gökdemir et al., 2022)

SDN1
CRISPR/Cas

Ondokuz Mayıs University
Burdur Mehmet Akif Ersoy University, Turkey

Generating male sterility lines (MLS). Using MLS in hybrid seed production reduces costs and ensures high purity of the varieties because it does not produce pollen and has exserted stigmas.
( Jung et al., 2020 )

SDN1
CRISPR/Cas

Hankyong National University
Hanyang University
Sunchon National University
Chungbuk National University
Tomato Research Center, South Korea

Traits related to product color/flavour

Brown color and increased sugar content.
( Kim et al., 2022 )

SDN1
CRISPR/Cas

Hankyong National University
Korea Polar Research Institute
Seoul National University College of Medicine
Chungbuk National University, South Korea

Fine-tuned anthocyanin biosynthesis.
( )

SDN1
CRISPR/Cas

Northeast Forestry University, Horticultural Sub-academy of Heilongjiang Academy of Agricultural Sciences, China
Wonsan University of Agriculture, South Korea

Traits related to storage performance

Enhanced storage potential of ripening fruits.
( Do et al., 2024 )

SDN1
CRISPR/Cas

Kyungpook National University
Sunchon National University
Catholic University of Korea, South Korea

Delayed onset of riping.
( Jeon et al., 2024 )

SDN1
CRISPR/Cas

Kyungpook National University
Sunchon National University, South Korea

Traits categories

Genome Editing Technique

Countries

Plant

Sdn Type

Traits related to biotic stress tolerance

Traits related to abiotic stress tolerance

Traits related to improved food/feed quality

Traits related to increased plant yield and growth

Traits related to industrial utilization

Traits related to product color/flavour

Traits related to storage performance