Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 64 results

Traits related to biotic stress tolerance

Viral resistance: to Cotton Leaf Curl Kokhran Virus, causing Cotton leaf curl disease (CLCuD), a very devastating and prevalent disease. CLCuD causes huge losses to the textile and other industries.
(Hamza et al., 2021)
SDN1
CRISPR/Cas
National Institute for Biotechnology and Genetic Engineering, Pakistan
Broad-spectrum resistance against multiple Potato virus Y (PVY)-strains.
( Noureen et al., 2022 )
SDN1
CRISPR/Cas
Constituent College of Pakistan Institute of Engineering and Applied Sciences (PIEAS)
University Institute of Biochemistry and Biotechnology (UIBB), Pakistan
Viral resistance: improved resistance against a tobamovirus, which could threaten tomato, tobacco, potato and squash plants.
(Miyoshi et al., 2024)
SDN1
CRISPR/Cas
Ehime University
Ehime Research Institute of Agriculture, Japan
Bacterial resistance: Strong resistance to Xanthomonas oryzae, causing bacterial blight, a devastating rice disease resulting in yield losses.
(Xu et al., 2021)
SDN1
TALENs
Shanghai Jiao Tong University, China
Crop Diseases Research Institute, Pakistan
Viral resistance: reduced cotton leaf curl viral (CLCuV) load with asymptomatic plants. <br /> CLCuV causes a very devastating and prevalent disease. It causes huge losses to textile and other industries.
(Shakoor et al., 2023)
SDN1
CRISPR/Cas
University of the Punjab
University of Gujrat, Pakistan
Pacific Biosciences
CureVac Manufacturing GmbH, Germany
Bacterial resistance: improved resistance to Xanthomonas oryzae, which causes bacterial blight, a devastating rice disease resulting in yield losses.
(Oliva et al., 2019)
SDN1
CRISPR/Cas
International Rice Research Institute, Philippines
University of Missouri
University of Florida
Iowa State University
Donald Danforth Plant Science Center, USA
Université Montpellier, France
Heinrich Heine Universität Düsseldorf
Max Planck Institute for Plant Breeding Research
Erfurt University of Applied Sciences, Germany
Nagoya University, Japan
Bacterial resistance: Strong resistance to Xanthomonas oryzae, causing bacterial blight, a devastating rice disease resulting in yield losses.
(Zafar et al., 2020)
SDN1
CRISPR/Cas
Constituent College of Pakistan Institute of Engineering and Applied Sciences
University of Information Technology
Engineering and Management Sciences
Constituent College of Pakistan Institute of Engineering and Applied Sciences, Pakistan
Viral resistance: increased resistance to chickpea chlorotic dwarf virus (CpCDV).
(Malik et al., 2023)
SDN1
CRISPR/Cas
University of the Punjab
University of Gujrat, Pakistan
Washington State University, USA
Viral resistance: Resistance to Tomato brown rugose fruit virus (ToBRFV), a major threat to the production of tomato.
(Ishikawa et al., 2022)
SDN1
CRISPR/Cas
Institute of Agrobiological Sciences
Takii and Company Limited, Japan
Fungal resistance: Increased tolerance against Fusarium oxysporum f. sp. lycopersici, causing vascular wilt.
(Ijaz et al., 2022)
SDN1
CRISPR/Cas
University of Agriculture, Pakistan
Fungal resistance: Reduced susceptibility to necrotrophic fungi. Necrotrophic fungi, such as Botrytis cinerea and Alternaria solani, cause severe damage in tomato production.
(Ramirez Gaona et al., 2023)
SDN1
CRISPR/Cas
Wageningen University &
Research, The Netherlands
Takii &
Company Limited, Japan
Viral resistance: enhanced resistance against chickpea chlorotic dwarf virus (CpCDV). The range of symptoms caused by CpCDV varies from mosaic pattern to streaks to leaf curling and can include browning of the collar region and stunting, foliar chlorosis and necrosis.
(Munir Malik et al., 2022)
SDN1
CRISPR/Cas
University of the Punjab
University of Gujrat, Pakistan
Washington State University, USA
Nematode resistance: decreased susceptibility against root-knot nematodes, showing fewer gall and egg masses.
(Noureddine et al., 2023)
SDN1
CRISPR/Cas
Université Côte d’Azur
Université de Toulouse, France
Kumamoto University, Japan

Traits related to abiotic stress tolerance

Enhanced responses to abscisic acid (ABA), which plays an important role in drought stress responses in plants. Improved drought tolerance through stomatal regulation and increased primary root growth under non-stressed conditions.
( Ogata et al., 2020 )
SDN1
CRISPR/Cas
Japan International Research Center for Agricultural Sciences (JIRCAS)
RIKEN Center for Sustainable Resource Science
University of Tsukuba, Japan
Improved lodging resistance.
( Wakasa et al., 2024 )
SDN1
CRISPR/Cas
Institute of Agrobiological Sciences
Institute of Crop Sciences, Japan
Increased tolerance to salinity stress. Improved rice yields in saline paddy fields by root angle modifications to adapt to climate change.
( Kitomi et al., 2020 )
SDN1
CRISPR/Cas
National Agriculture and Food Research Organization (NARO)
Tohoku University
Institute of Agrobiological Sciences
Japan Science and Technology Agency (JST)
Advanced Analysis Center
National Institute of Advanced Industrial Science and Technology (AIST), Japan
Higher tolerance to salt and osmotic stress through reduced stomatal conductance coupled with increased leaf relative water content and Abscisic acid (ABA) content under normal and stressful conditions.
( Bouzroud et al., 2020 )
SDN1
CRISPR/Cas
Université Mohammed V de Rabat, Morocco
Université de Toulouse, France
Universidade Federal de Viçosa, Brazil

Traits related to improved food/feed quality

Increased NH4+ and PO43− uptake, and photosynthetic activity under high CO2 conditions in rice. Largely increased panicle weight. Improved grain appearance quality or a decrease in the number of chalky grains.
( Iwamoto et al., 2022 )
SDN1
CRISPR/Cas
Institute of Agrobiological Sciences, Japan
Complete abolition of glycoalkaloids, causing a bitter taste and toxic to various organisms.
( Nakayasu et al., 2018 )
SDN1
CRISPR/Cas
Kobe University, Japan
Increased flavonoid content, functioning as allelochemicals and insect deterrents.
( Lam et al., 2019 )
SDN1
CRISPR/Cas
The University of Hong Kong
The Chinese University of Hong Kong
Shenzhen
Zhejiang Academy of Agricultural Sciences
Nanjing Forestry University, China
Kyoto University, Japan
Negligible levels of the possibly toxic steroidal glykoalkaloids (SGAs), but enhanced levels of steroidal saponins, which has pharmaceutically useful functions.
( Akiyama et al., 2017 )
SDN1
CRISPR/Cas
Kobe University
Riken Center for Sustainable Resource Science
Osaka University, Japan
Amylose-free tubers.
( Abeuova et al., 2023 )
SDN1
CRISPR/Cas
National Center for Biotechnology (NCB)
L.N. Gumilyov Eurasian National University
Nazarbayev University, Kazakhstan
Reduction of harmful ingredients: toxic steroidal glycoalkaloids (SGAs).
(Sawai et al., 2014)
SDN1
TALENs
RIKEN Center for Sustainable Resource Science
Chiba University, Japan
Reduce malnutrition by decreasing antinutrient phytic acid (PA) and increasing Iron and Zinc accumulation. PA has adverse effects on essential mineral absorption and thus is considered as an anti-nutritive for monogastric animals.
( Ibrahim et al., 2021 )
SDN1
CRISPR/Cas
Quaid-i-Azam University Islamabad
National Agricultural Research Centre, Pakistan
High gamma-aminobutyric acid (GABA) content. GABA plays a key role in plant stress responses, growth, development and as a nutritional component of grain can also reduce the likelihood of hypertension and diabetes. Increased amino acid content. Higher seed weight and seed protein content.
( Akama et al., 2020 )
SDN1
CRISPR/Cas
Shimane University
Institute of Agrobiological Sciences
National Agriculture and Food Research Organization
Yokohama City University, Japan
Increased gamma-Aminobutyric acid (GABA) accumulation by 7 to 15 fold while having variable effects on plant and fruit size and yield. GABA is a nonproteogenic amino acid and has health-promoting functions.
( Nonaka et al., 2017 )
SDN1
CRISPR/Cas
University of Tsukuba, Japan
Reduced content of anti-nutritional factors in soybean seeds, leading to improved digestibility.
( Figliano et al., 2023 )
SDN1
CRISPR/Cas
UEL - Universidade Estadual de Londrina, Portugal
Seedless tomatoes for industrial purposes and direct eating quality.
( Ueta et al., 2017 )
SDN1
CRISPR/Cas
Tokushima University, Japan
Reduces phytic acid (anti-nutrient) and improves iron and zinc accumulation in wheat grains. Biofortification.
( Ibrahim et al., 2021 )
SDN1
CRISPR/Cas
Quaid-i-Azam University Islamabad
National Agricultural Research Centre, Pakistan
Reduced steroidal glycoalkaloids.
( Yasumoto et al., 2019 )

TALENs
Osaka University
RIKEN Center for Sustainable Resource Science
Kobe University, Japan
Carotenoid accumulation to solve the problem of vitamin A deficiency that is prevalent in developing countries.
( Endo et al., 2019 )
SDN1
CRISPR/Cas
National Agriculture and Food Research Organization
Ishikawa Prefectural University, Japan
Increased carotenoid, lycopene, and β-carotene.
( Hunziker et al., 2020 )

BE
University of Tsukuba
Kobe University
Institute of Vegetable and Floricultural Science
NARO, Japan
Important metabolic changes affecting tomato fruit quality. Reduced contents of the anti-nutrient oxalic acid.
( Gago et al., 2017 )
SDN1
ZFN
University of Algarve, Portugal
Centre for Research and Technology Hellas
Technological Educational Institution of Crete, Greece
High-quality sugar production by rice (98% sucrose content). Carbohydrates are an essential energy-source. Sugarcane and sugar beet were the only two crop plants used to produce sugar.
( Honma et al., 2020 )
SDN1
CRISPR/Cas
Fujian Agriculture and Forestry University, China
Faculty of Engineering
Kitami Institute of Technology
NagoyaUniversity
Tokyo Metropolitan University, Japan
Carnegie Institution for Science, USA
Improved cold storage and processing traits: lower levels of reduced sugars
(Yasmeen et al., 2022)
SDN1
CRISPR/Cas
University of the Punjab, Pakistan
Increased sugar content without decreased fruit weight. Sugar content is one of the most important quality traits of tomato.
( Kawaguchi et al., 2021 )
SDN1
CRISPR/Cas
Nagoya University
Kobe University
RIKEN Center for Sustainable Resource Science
University of Tsukuba, Japan
Altered fatty acid composition. High oleic/low linoleic acid rice. Oleic acid has potential health benefits and helps decrease lifestyle disease.
( Abe et al., 2018 )
SDN1
CRISPR/Cas
National Agriculture and Food Research Organization, Japan
Improved fatty acid composition. The content and abundance of fatty acids play an important role in nutritional and processing applications of oilseeds.
( Okuzaki et al., 2018 )
SDN1
CRISPR/Cas
Tamagawa University
Osaka Prefecture University
Tamagawa University, Japan

Traits related to increased plant yield and growth

Altered plant architecture to inrease yield: increased node number on the main stem and branch number.
(Bao et al., 2019)
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences
Huazhong Agricultural University, China
Duy Tan University, Vietnam
RIKEN Center for Sustainable Resource Science, Japan
Altered root architecture with increased tillers and total grain weight.
( Rahim et al., 2023 )
SDN1
CRISPR/Cas
Quaid-e-Azam University
National Agricultural Research Centre (NARC)
The University of Haripur, Pakistan
King Saud University, Saudi Arabia
Nile University
Ain Shams University, Egypt
Chonnam National University, South Korea
Improved nitrogen use efficiency, growth and yield in low nitrogen environment.
( Liu et al., 2023 )
SDN1
CRISPR/Cas
The University of Tokyo, Japan
Range of beneficial phenotypes: additional tillers and smaller culms and panicles.
(Cui et al., 2020)
SDN1
CRISPR/Cas
China National Rice Research Institute
Huazhong Agricultural University, China
Yangzhou University, Nagoya University, Japan
Regulating fruit ripening, one of the most important concerns in the study of fleshy fruit species.
( Ito et al., 2015 )
SDN1
CRISPR/Cas
National Food Research Institute, Japan
Reduction of plant height through accumulation of ceramides. Plant height is an important agronomic trait of rice, it directly affects the yield potential and lodging resistance.
( Wang et al., 2023 )
SDN1
CRISPR/Cas
Nanchang University
Henan Agricultural University, China
Hokkaido University, Japan
Increased grain yield under phosphorus-deficient conditions.
( Ishizaki et al., 2022 )
SDN1
CRISPR/Cas
Japan International Research Center for Agricultural Sciences (JIRCAS), Japan
Increase in 1000-grain weight, grain area, grain width, grain length, plant height, and spikelets per spike.
( Errum et al., 2023 )
SDN1
CRISPR/Cas
National Agricultural Research Centre (NARC)
PARC Institute of Advanced Studies in Agriculture (PIASA)
Pakistan Agricultural Research Council, Pakistan
Increased tiller number and grain yield.
( Cui et al., 2023 )
SDN1
CRISPR/Cas
The University of Tokyo
Kyoto University
National Institute of Crop Science, Japan
Elongated, occasionally peanut-like shaped fruit.
( Zheng et al., 2022 )
SDN1
CRISPR/Cas
Nagoya University
Kanazawa University, Japan
Huazhong Agricultural University, China
Increased tiller number.
( Awan et al., 2024 )
SDN1
CRISPR/Cas
National Institute for Biotechnology and Genetic Engineering
Quaid-i-Azam University, Pakistan

Traits related to industrial utilization

Restoring cytoplasmic sterility.
( Kazama et al., 2019 )
SDN2
TALENs
Tohoku University
Tamagawa University
The University of Tokyo
National Institute of Genetics
Tokyo Institute of Technology
Tamagawa University
Japan Science and Technology Agency, Japan
Early heading: in regions with short growing seasons, early maturing varieties to escape frost damage are required.
(Sohail et al., 2022)
SDN1
CRISPR/Cas
China National Rice Research Institute
Northern Center of China National Rice Research Institute
Zhejiang A&
F University, China
Mir Chakar Khan Rind University
Agriculture Research System Khyber, Pakistan
Ministry of Agriculture, Bangladesh
Agriculture Research Center, Egypt
Significantly longer seed dormancy period, may result in reduced pre-harvest sprouting of grains on spikes.
( Abe et al., 2019 )
SDN1
CRISPR/Cas
Institute of Crop Science
Okayama University
Yokohama City University
Institute of Agrobiological Sciences
Obihiro University of Agriculture and Veterinary Medicine, Japan
Dwarf plants that retain favourable fruit traits.
( Nagamine et al., 2024 )
SDN1
CRISPR/Cas
University of Tsukuba, Japan
Production of herbicide-sensitive strain to prevent volunteer infestation. Volunteer rice grows when cultivated rice seed fall into fields, overwinter and spontaneously germinate the next spring.
( Komatsu et al., 2020 )

BE
Institute of Agrobiological Sciences
National Agriculture and Food Research Organization (NARO)
Graduate School of Science
Technology and Innovation, Japan
Fertility restoration of cytoplasmic male sterility.
( Suketomo et al., 2020 )
SDN1
CRISPR/Cas
Tohoku University, Japan
Confer male and female sterility to prevent the risk of trasgene flow from transgenic plants to their wild relatives.
( Shinoyama et al., 2020 )
SDN1
TALENs
Fukui Agricultural Experiment Station
Institute of Agrobiological Sciences
National Agriculture and Food Research Organization (NARO)
Japan Science and Technology Agency (JST)
Yokohama City University, Japan
Altai State University, Russia

Traits related to herbicide tolerance

Imazamox
( Shimatani et al. 2017 )

BE
Kobe University
University of Tsukuba
Meijo University, Japan
Herbicide resistance
( Shimatani et al. 2018 )

BE
Kobe University, Japan
University of Tsukuba, Japan
Herbicide tolerance: ALS-inhibiting
(Okuzaki et al., 2004)

ODM
Tohoku University, Japan
Resistance to ALS-inhibiting herbicides.
( Okuzaki et al., 2003 )

ODM
Tohoku University, Japan
Herbicide tolerance: Bispyribac-sodium (BS). BS is a pyrimidinyl carboxy herbicide.
(Zafar et al., 2023)
SDN2
CRISPR/Cas
Constituent College of Pakistan Institute of Engineering and Applied Sciences
Engineering and Management Sciences (BUITEMS), Pakistan

Traits related to product color/flavour

Flower color modification due to reduced anthocyanin content. Flower color is one of the most important traits in ornamental flowers.
( Nishihara et al. (2018) )
SDN1
CRISPR/Cas
Iwate Biotechnology Research Center, Japan
Color modification: yellow. Ipomoea nil exhibits a variety of flower colours, except yellow.
(Watanabe et al., 2018)
SDN1
CRISPR/Cas
University of Tsukuba
National Agriculture and Food Research Organization, Japan

Traits related to storage performance

The fruit remains green and shows higher firmness as well as no early fermentation. This results in extended shelf-life which could reduce food loss and contribute to food security.
( Nonaka et al., 2023 )
SDN1
CRISPR/Cas
University of Tsukuba, Japan