Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 23 results

Traits related to improved food/feed quality

Reduce malnutrition by decreasing antinutrient phytic acid (PA) and increasing Iron and Zinc accumulation. PA has adverse effects on essential mineral absorption and thus is considered as an anti-nutritive for monogastric animals.
( Ibrahim et al., 2021 )
SDN1
CRISPR/Cas
Quaid-i-Azam University Islamabad
National Agricultural Research Centre, Pakistan
Improved fatty acid composition. The content and abundance of fatty acids play an important role in nutritional and processing applications of oilseeds.
( Okuzaki et al., 2018 )
SDN1
CRISPR/Cas
Tamagawa University
Osaka Prefecture University
Tamagawa University, Japan
Altered gliadin levels resulting in improved end-use quality and reduced gluten epitopes associated with celiac disease. Gliadins are important for wheat end-use traits.
( Liu et al., 2023 )
SDN1
CRISPR/Cas
China Agricultural University, China
Research Centre for Cereal and Industrial Crops, Italy
Increased NH4+ and PO43− uptake, and photosynthetic activity under high CO2 conditions in rice. Largely increased panicle weight. Improved grain appearance quality or a decrease in the number of chalky grains.
( Iwamoto et al., 2022 )
SDN1
CRISPR/Cas
Institute of Agrobiological Sciences, Japan
Complete abolition of glycoalkaloids, causing a bitter taste and toxic to various organisms.
( Nakayasu et al., 2018 )
SDN1
CRISPR/Cas
Kobe University, Japan
Reduces phytic acid (anti-nutrient) and improves iron and zinc accumulation in wheat grains. Biofortification.
( Ibrahim et al., 2021 )
SDN1
CRISPR/Cas
Quaid-i-Azam University Islamabad
National Agricultural Research Centre, Pakistan
Increased flavonoid content, functioning as allelochemicals and insect deterrents.
( Lam et al., 2019 )
SDN1
CRISPR/Cas
The University of Hong Kong
The Chinese University of Hong Kong
Shenzhen
Zhejiang Academy of Agricultural Sciences
Nanjing Forestry University, China
Kyoto University, Japan
Mutant cell lines doubled the accumulation level of anthocyanins biosynthesized. The production of these important pigments was stabilized over time.
( D'Amelia et al., 2022 )
SDN1
CRISPR/Cas
National Research Council of Italy
University of Naples Federico II
Council for Agricultural Research and Economics, Italy
Negligible levels of the possibly toxic steroidal glykoalkaloids (SGAs), but enhanced levels of steroidal saponins, which has pharmaceutically useful functions.
( Akiyama et al., 2017 )
SDN1
CRISPR/Cas
Kobe University
Riken Center for Sustainable Resource Science
Osaka University, Japan
Reduction of harmful ingredients: toxic steroidal glycoalkaloids (SGAs).
(Sawai et al., 2014)
SDN1
TALENs
RIKEN Center for Sustainable Resource Science
Chiba University, Japan
Improved cold storage and processing traits: lower levels of reduced sugars
(Yasmeen et al., 2022)
SDN1
CRISPR/Cas
University of the Punjab, Pakistan
High gamma-aminobutyric acid (GABA) content. GABA plays a key role in plant stress responses, growth, development and as a nutritional component of grain can also reduce the likelihood of hypertension and diabetes. Increased amino acid content. Higher seed weight and seed protein content.
( Akama et al., 2020 )
SDN1
CRISPR/Cas
Shimane University
Institute of Agrobiological Sciences
National Agriculture and Food Research Organization
Yokohama City University, Japan
Starch with an increased amylose ratio and elongated amylopectin chains. In food products, high amylose content and long amylopectin chains contribute to a low glycaemic index (GI) after intake, playing a role in health benefits.
( Zhao et al., 2021 )
SDN1
CRISPR/Cas
Swedish University of Agricultural Sciences, Sweden
Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET)
Laboratorio de Agrobiotecnología (INTA), Argentina
Increased gamma-Aminobutyric acid (GABA) accumulation by 7 to 15 fold while having variable effects on plant and fruit size and yield. GABA is a nonproteogenic amino acid and has health-promoting functions.
( Nonaka et al., 2017 )
SDN1
CRISPR/Cas
University of Tsukuba, Japan
Seedless tomatoes for industrial purposes and direct eating quality.
( Ueta et al., 2017 )
SDN1
CRISPR/Cas
Tokushima University, Japan
Lowering phytate synthesis in seeds. Phytate is an anti-nutritient.
( Vlčko and Ohnoutková, 2020 )
SDN1
CRISPR/Cas
Czech Academy of Sciences, Czech Republic
Reduced steroidal glycoalkaloids.
( Yasumoto et al., 2019 )

TALENs
Osaka University
RIKEN Center for Sustainable Resource Science
Kobe University, Japan
Carotenoid accumulation to solve the problem of vitamin A deficiency that is prevalent in developing countries.
( Endo et al., 2019 )
SDN1
CRISPR/Cas
National Agriculture and Food Research Organization
Ishikawa Prefectural University, Japan
Increased carotenoid, lycopene, and β-carotene.
( Hunziker et al., 2020 )

BE
University of Tsukuba
Kobe University
Institute of Vegetable and Floricultural Science
NARO, Japan
High-quality sugar production by rice (98% sucrose content). Carbohydrates are an essential energy-source. Sugarcane and sugar beet were the only two crop plants used to produce sugar.
( Honma et al., 2020 )
SDN1
CRISPR/Cas
Fujian Agriculture and Forestry University, China
Faculty of Engineering
Kitami Institute of Technology
NagoyaUniversity
Tokyo Metropolitan University, Japan
Carnegie Institution for Science, USA
Reduce allergen proteins. Structural and metabolic proteins, like α-amylase/trypsin inhibitors are involved in the onset of wheat allergies (bakers' asthma) and probably Non-Coeliac Wheat Sensitivity (NCWS).
( Camerlengo et al., 2020 )
SDN1
CRISPR/Cas
University of Tuscia, Italy
Rothamsted Research, UK
Impasse Thérèse Bertrand-Fontaine, France
Increased sugar content without decreased fruit weight. Sugar content is one of the most important quality traits of tomato.
( Kawaguchi et al., 2021 )
SDN1
CRISPR/Cas
Nagoya University
Kobe University
RIKEN Center for Sustainable Resource Science
University of Tsukuba, Japan
Altered fatty acid composition. High oleic/low linoleic acid rice. Oleic acid has potential health benefits and helps decrease lifestyle disease.
( Abe et al., 2018 )
SDN1
CRISPR/Cas
National Agriculture and Food Research Organization, Japan