Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Genome Editing Technique

Displaying 31 results

Traits related to biotic stress tolerance

Fungal resistance: effective reduction of susceptibility against downy mildew by increasing salicylic acid levels. The pathogen can devastate individual vineyards and in some cases also affect production from entire regions.
(Giacomelli et al., 2023)
SDN1
CRISPR/Cas
Research and Innovation Centre
Fondazione Edmund Mach, Italy
Enza Zaden
Hudson River Biotechnology, The Netherlands
Viral resistance: increased control on viral pathogen Banana streak virus (BSV). The BSV integrates in the banana host genome as endogenous BSV (eBSV). When banana plants are stressed, the eBSV produces infectious viral particles and thus the plant develops disease symptoms.
(Tripathi et al., 2019)
SDN1
CRISPR/Cas
International Institute of Tropical Agriculture (IITA), Kenya
University of California, USA
Bacterial resistance: Enhanced resistance to Xanthomonas campestris pv. musacearum, causing Bananas Xanthomonas wilt (BXW). Overall economic losses caused by Xanthomonas campestris were estimated at 2-8 billion USD over a decade.
(Tripathi et al., 2021)
SDN1
CRISPR/Cas
International Institute of Tropical Agriculture (IITA), Kenya
Resistance to parasitic weed: Striga spp. The parasitic plant reduces yields of cereal crops worldwide.
(Hao et al., 2023)
SDN1
CRISPR/Cas
University of Nebraska-Lincoln
Pennsylvania State University, USA
International Maize and Wheat Improvement Center (CIMMYT), Senegal
Kenyatta University, Kenya

Fungal resistance: Reduced susceptibility to the powdery mildew pathogen (Oidium neolycopersici), a world-wide disease threatening the production of greenhouse- and field-grown tomatoes.
(Santillán Martínez et al., 2020)
SDN1
CRISPR/Cas
Wageningen University &
Research, The Netherlands
Fungal resistance: increased resistance against powdery mildew, a destructive disease that threatens cucumber production globally.
(Dong et al., 2023)
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences, China
University of California Davis, USA
Wageningen University &
Research, The Netherlands
Viral resistance: increased resistance to infection with the potato virus Y (PVY) and tolerance to salt and osmotic stress. PVY is one of the most economically important potato pathogens
(Makhotenko et al., 2019)
SDN1
CRISPR/Cas
Russia Moscow State University, Russia
Doka Gene Technologies Ltd, USA
Significantly enhanced resistance to V. dahliae, and furthermore also to Verticillium albo-atrum and Fusarium oxysporum f. sp. lycopersici (Fol), despite severe growth defects.
( Hanika et al., 2021 )
SDN1
CRISPR/Cas
Wageningen University &
Research, The Netherlands
Fungal resistance: Reduced susceptibility to necrotrophic fungi. Necrotrophic fungi, such as Botrytis cinerea and Alternaria solani, cause severe damage in tomato production.
(Ramirez Gaona et al., 2023)
SDN1
CRISPR/Cas
Wageningen University &
Research, The Netherlands
Takii &
Company Limited, Japan
Fungal resistance: Enhanced resistance against powdery mildew, caused by Oidium neolycopersici, which is a major concern for the productivity of tomato plants.
(Li et al., 2024)
SDN1
CRISPR/Cas
University of Torino, Italy
Wageningen University &
Research, The Netherlands
Shanxi Agricultural University, China
Viral resistance: enhanced resistance against wheat dwarf virus, which is a causal agent of wheat viral disease and can significantly impact wheat production worldwide.
(Yuan et al., 2024)
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences
Northwest A&
F University, China

Norwegian Institute of Bioeconomy Research, Norway
Bacterial resistance: resistance against banana Xanthomonas wilt (BXW) disease, caused by Xanthomonas campestris pv. musacearum. BXW forms a great threat to banana cultivation in East and Central Africa.
(Ntui et al., 2023)
SDN1
CRISPR/Cas
International Institute of Tropical Agriculture, Kenya

Traits related to abiotic stress tolerance

Increased drought-avoidance strategy.
( Maioli et al., 2024 )
SDN1
CRISPR/Cas
University of Torino, Italy
Ingeniero Fausto Elio/n, Spain
Wageningen University &
Research, The Netherlands
Increased tolerance to drought trough reducing water loss. Tuber development.
( Gonzales et al., 2020 )
SDN1
CRISPR/Cas
Wageningen University and Research, The Netherlands
Centro Nacional de Biotecnología – CSIC
Universidad Politécnica de Madrid (UPM), Spain
Increased salt-tolerance.
( Antonova et al., 2024 )
SDN1
CRISPR/Cas
Institute of Plant and Animal Ecology (IPAE)
N.I. Vavilov All-Russian Institute of Plant Genetic Resources (VIR)
Institute of Cytology and Genetics (ICG), Russia
Drought tolerance.
( Njuguna et al., 2018 )
SDN1
CRISPR/Cas
Ghent University
Center for Plant Systems Biology, Belgium
Jomo Kenyatta University of Agriculture and Technology, Kenya

Traits related to improved food/feed quality

Improved kafirin digestibility, which increases the grain nutritional value.
( Elkonin et al., 2023 )
SDN1
CRISPR/Cas
Federal Centre of Agriculture Research of South-East Region
Institute of Biochemistry and Genetics – Subdivision of the Ufa Federal Research Centre of the Russian Academy of Sciences, Russia
Glossy sheat phenotype.
( Gerasimova et al., 2023 )
SDN1
CRISPR/Cas
Siberian Branch of the Russian Academy of Sciences
Vavilov Institute of Plant Genetic Resources (VIR)
Siberian Branch of the Russian Academy of Sciences, Russia

Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Germany
Improved digestibility of kafirins, which increases the grain nutritional value.
( Elkonin et al., 2023 )
SDN1
CRISPR/Cas
Federal Centre of Agriculture Research of South-East Region
Institute of Biochemistry and Genetics, Russia

Traits related to increased plant yield and growth

Increased total kernel number or kernel weight.
( Kelliher et al., 2019 )
SDN1
CRISPR/Cas
Research Triangle Park
University of Georgia, USA
Syngenta Crop Protection, The Netherlands
Various phenotypic changes were observed of which traits such as plant dwarfing, color, shape, and weight, early flowering, a high number of flowers and early fruit set and maturation, fewer seeds, and reduced and delayed browning of fruits are agronomically important.
( Kodackattumannil et al., 2023 )
SDN1
CRISPR/Cas
United Arab Emirates University, United Arab Emirates
Altered spike architecture.
( de Souza Moraes et al., 2022 )
SDN1
CRISPR/Cas
Wageningen University and Research, The Netherlands
Universidade de São Paulo, Brazil
Norwich Research Park, UK
Rheinische Friedrich-Wilhelms-Universität, Germany

Traits related to industrial utilization

Increasing cross over frequency. Cross over formation during meiosis is essential for crop breeding to introduce favourable alleles controlling important traits from wild relatives into crops.
( de Maagd et al., 2020 )
SDN1
CRISPR/Cas
Wageningen University &
Research, The Netherlands
Generate self-compatible diploid potato lines for the application of efficient breeding methods.
( Eggers et al., 2021 )
SDN3
CRISPR/Cas
Solynta
Wageningen University &
Research, The Netherlands
Establishment of maternal haploid induction. Doubled haploid technology is used to obtain homozygous lines in a single generation. This technique significantly accelerates the crop breeding trajectory.
( Zhong et al., 2022 )
SDN1
CRISPR/Cas
China Agricultural University, China
Wageningen University and Research, The Netherlands
Confer male and female sterility to prevent the risk of trasgene flow from transgenic plants to their wild relatives.
( Shinoyama et al., 2020 )
SDN1
TALENs
Fukui Agricultural Experiment Station
Institute of Agrobiological Sciences
National Agriculture and Food Research Organization (NARO)
Japan Science and Technology Agency (JST)
Yokohama City University, Japan
Altai State University, Russia
Establishment of maternal haploid induction. Doubled haploid technology is used to obtain homozygous lines in a single generation. This technique significantly accelerates the crop breeding trajectory.
( Zhong et al., 2022 )
SDN1
CRISPR/Cas
China Agricultural University, China
Wageningen University and Research, The Netherlands

Traits related to herbicide tolerance

Dinitroanaline
( Liu et al., 2021 )

BE
Chinese Academy of Agricultural Sciences
China Agricultural University
Zhejiang University
Scientific Observing and Experimental Station of Crop Pests in Guilin, Ministry of Agriculture and Rural Affairs, China
Norwegian Institute of Bioeconomy Research, Norway
Bispyribac sodium
( Kuang et al., 2020 )

BE
Chinese Academy of Agricultural Sciences
China Agricultural University
Zhejiang University, China
Norwegian Institute of Bioeconomy Research, Norway

Traits related to product color/flavour

Albino phenotype.
( Syombua et al., 2021 )
SDN1
CRISPR/Cas
International Institute of Tropical Agriculture (IITA)
University of Nairobi, Kenya
University of Missouri
Iowa State University
Donald Danforth Plant Science Center, USA

Traits related to storage performance

Extended root shelf-life, which decreases its wastage.
( Mukami et al., 2023 )
SDN1
CRISPR/Cas
Kenyatta University
Jomo Kenyatta University of Agriculture Technology
Pwani University Kilifi, Kenya