genome search | EU-SAGE

Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 50 results

Traits related to biotic stress tolerance

Viral resistance: partial resistance to Pepper veinal mottle virus (PVMV) isolate IC, with plants harboring weak symptoms and low virus loads at the systemic level.
(Moury et al., 2020)

SDN1
CRISPR/Cas

INRA, France
Université de Tunis El-Manar
Université de Carthage, Tunisia
Université Felix Houphouët-Boigny, Cote d’Ivoire
Institut de l’Environnement et de Recherches Agricoles, Burkina Faso

High resistance to powdery mildew under semi-commercial growth conditions.
( Shnaider et al., 2022 )

SDN1
CRISPR/Cas

Agricultural Research Organization Volcani Center, Israel

Resistance to parasitic weed: Phelipanche aegyptiaca. The obligate root parasitic plant causes great damages to important crops and represents one of the most destructive and greatest challenges for the agricultural economy.
(Bari et al., 2019)

SDN1
CRISPR/Cas

Newe Ya’ar Research Center,
Agricultural Research Organization (ARO), Israel
University of California, USA

Increased basal immunity and broad spectrum disease resistance.
( Leibman-Markus et al., 2023 )

SDN1
CRISPR/Cas

Volcani Institute
Tel Aviv University, Israel

Bacterial resistance: resistance against banana Xanthomonas wilt (BXW) disease, caused by Xanthomonas campestris pv. musacearum. BXW forms a great threat to banana cultivation in East and Central Africa.
(Ntui et al., 2023)

SDN1
CRISPR/Cas

International Institute of Tropical Agriculture, Kenya

Broad-spectrum disease resistance without yield loss.
( Sha et al., 2023 )

SDN1
CRISPR/Cas

Huazhong Agricultural University
Chengdu Normal University
Jiangxi Academy of Agricultural Sciences
Anhui Agricultural University
BGI-Shenzhen
Northwest A&
F University
Shandong Academy of Agricultural Sciences, China
Université de Bordeaux, France
University of California
The Joint BioEnergy Institute, USA
University of Adelaide, Australia

Viral resistance: increased control on viral pathogen Banana streak virus (BSV). The BSV integrates in the banana host genome as endogenous BSV (eBSV). When banana plants are stressed, the eBSV produces infectious viral particles and thus the plant develops disease symptoms.
(Tripathi et al., 2019)

SDN1
CRISPR/Cas

International Institute of Tropical Agriculture (IITA), Kenya
University of California, USA

Virus resistance: Immunity to cucumber vein yellowing virus infection (Ipomovirus) and resistance to the potyviruses Zucchini yellow mosaic virus and Papaya ring spot mosaic virus.
(Chandrasekaran et al., 2016)

SDN1
CRISPR/Cas

Volcani Center, Israel

Bacterial resistance: Enhanced resistance to Xanthomonas campestris pv. musacearum, causing Bananas Xanthomonas wilt (BXW). Overall economic losses caused by Xanthomonas campestris were estimated at 2-8 billion USD over a decade.
(Tripathi et al., 2021)

SDN1
CRISPR/Cas

International Institute of Tropical Agriculture (IITA), Kenya

SDN1
CRISPR/Cas

Central University of Punjab, India
Newe Ya’ar Research Center
Agricultural Research Organization (ARO), Israel

Viral resistance: Reduced viral load and symptoms after bean yellow dwarf virus (BeYDV) infection.
(Baltes et al., 2015)

SDN1
CRISPR/Cas

University of Minnesota
The Ohio State University, USA
Institute of Biophysics ASCR, Czech Republic

Resistance to parasitic weed: Striga spp. The parasitic plant reduces yields of cereal crops worldwide.
(Hao et al., 2023)

SDN1
CRISPR/Cas

University of Nebraska-Lincoln
Pennsylvania State University, USA
International Maize and Wheat Improvement Center (CIMMYT), Senegal
Kenyatta University, Kenya

Viral resistance: resistance to potyvirus potato virus Y (PVY), which causes serious yield loss.
(Kumar et al., 2022)

SDN1
CRISPR/Cas

Agricultural Research Organization, Israel

Traits related to abiotic stress tolerance

Increased tolerance to salinity stress. Development of lines with reduced inositol hexakisphosphate (IP6) content may enhance phosphate and mineral bioavailability. ICP6 is a major storage form of phosphate in cereal grains.
( Vicko et al., 2020 )

SDN1
CRISPR/Cas

Czech Academy of Sciences, Czech Republic

Increased drought tolerance: suppresses xylem vessel proliferation, leading to lower water conductance, and reduced water-loss under water-deficit conditions.
(Illouz-Eliaz et al., 2020)

SDN1
CRISPR/Cas

Institute of Plant Sciences and Genetics in Agriculture
The Robert H. Smith Faculty of Agriculture
The Hebrew University of Jerusalem, Israel

Increased root length, which can restore good performance under water stress.
( Gabay et al., 2023 )

SDN1
CRISPR/Cas

University of California
Howard Hughes Medical Institute, USA
University of Haifa, Israel
Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET)
Universidad Nacional de San Martín (UNSAM), Argentina
Fudan University
China Agricultural University, China
Karolinska Institutet, Sweden

Drought tolerance.
( Njuguna et al., 2018 )

SDN1
CRISPR/Cas

Ghent University
Center for Plant Systems Biology, Belgium
Jomo Kenyatta University of Agriculture and Technology, Kenya

Increased tolerance to cold stress.
( Teper-Bamnolker et al., 2022 )

SDN1
CRISPR/Cas

The Volcani Institute
The Hebrew University of Jerusalem
Danziger Innovations Limited, Israel

Altered cuticle properties to enhance drought tolerance.
( Negin et al., 2021 )

SDN1
CRISPR/Cas

Weizmann Institute of Science, Israel

Drought and salt tolerance.
( Curtin et al., 2018 )

SDN1
CRISPR/Cas

University of Minnesota, USA
The University of Newcastle, Australia

Traits related to improved food/feed quality

Changing grain composition: decrease in the prolamines, an increase in the glutenins, increased starch content, amylose content, and β-glucan content. The protein matrix surrounding the starch granules was increased.
(Yang et al., 2020)

SDN1
CRISPR/Cas

Sichuan Agricultural University, China
Norwich Research Park, UK
CSIRO Agriculture and Food, Australia

Highly specific detection of Ochratoxin A (OTA) in cereal samples. OTA is classified as a Class 2B carcinogens. The method can be flexibly customized to detect a wide range of small molecular targets and holds great promise as a versatile sensing kit with applications in various fields requiring sensitive and specific detection of diverse analytes.
( Chen et al., 2023 )

SDN1
CRISPR/Cas

Ningbo University
Hainan University
Ningbo Clinical Pathology Diagnosis Center, China
University of New South Wales, Australia

Specific differences in grain morphology, composition and (1,3;1,4)-β-glucan content. Barley rich in (1,3;1,4)-β-glucan, a source of fermentable dietary fibre, is useful to protect against various human health conditions. However, low grain (1,3;1,4)-β-glucan content is preferred for brewing and distilling.
( Garcia-Gimenez et al., 2020 )

SDN1
CRISPR/Cas

The James Hutton Institute
University of Dundee, UK
University of Adelaide
La Trobe University, Australia

Lowering phytate synthesis in seeds. Phytate is an anti-nutritient.
( Vlčko and Ohnoutková, 2020 )

SDN1
CRISPR/Cas

Czech Academy of Sciences, Czech Republic

Fine-tuning the amylose content, one of the major contributors to the eating and cooking quality.
( Xu et al., 2021 )

Jiangsu Academy of Agricultural Sciences/Nanjing Branch of Chinese National Center for Rice Improvement
Yangzhou University
Chinese Academy of Sciences, China
CSIRO Agriculture and Food, Australia

Parthenocarpy: seedless tomato. Industrial purposes and direct eating quality.
(Klap et al., 2016)

SDN1
CRISPR/Cas

Agricultural Research Organization, Israel

Low glutelin content in the rice germplasm: patients with chronic kidney disease (CKD) and phenylketonuria (PKU) need to eat rice with low glutelin content.
(Chen et al., 2022)

SDN1
CRISPR/Cas

Nanjing Branch of Chinese National Center for Rice Improvement
Yangzhou University
Henan Agricultural University
Jiangsu Academy of Agricultural Sciences, China
CSIRO Agriculture and Food, Australia

Reduced amount of saturated fatty acids (FA) in soybean seeds for nutrititional improvement. FA are linked to cardiovascular diseases.
( Ma et al., 2021 )

SDN1
CRISPR/Cas

Zhejiang University, China
La Trobe University, Australia

Reduced browning and acrylamide. Acrylamide is a contaminant which forms during the baking, toasting and high-temperature processing of foods and is regarded as a potential carcinogen and neurotoxin.
( Nguyen Phuoc Ly et al., 2023 )

SDN1
CRISPR/Cas

Murdoch University, Australia

Reduced flavonoids and improved fatty acid composition with higher linoleic acid and linolenic acid, valuable for rapeseed germplasm and breeding. The genetic improvement has great significance in the economic value of rapeseeds.
( Xie et al., 2020 )

SDN1
CRISPR/Cas

Yangzhou University
The Ministry of Education of China, China
University of Western Australia, Australia

Reduced levels of very long chain saturated fatty acids in kernels, which are associated with revalance of atherosclerosis and cardiovascular disease.
( Huai et al., 2024 )

SDN1
CRISPR/Cas

Oil Crops Research Institute of Chinese Academy of Agricultural Sciences, China
International Crops Research Institute of the Semi-Arid Tropics (ICRISAT), India
Murdoch University, Australia

Traits related to increased plant yield and growth

Customize tomato cultivars for urban agriculture: increased compactness and decreased growth cycle of tomato plants.
(Kwon et al., 2020)

SDN1
CRISPR/Cas

Cold Spring Harbor Laboratory
Cornell University
University of Florida, USA
Wonkwang University, South Korea
Weizmann Institute of Science, Israel

Increased yield: plants produced more tillers and grains than azygous wild-type controls and the total yield was increased up to 15 per cent.
(Holubova et al., 2018)

SDN1
CRISPR/Cas

Palacký University
Centre of the Region Haná for Biotechnological and Agricultural Research, Czech Republic
Leibniz Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben, Germany

Positive regulation for grain dormancy. Lack of grain dormancy in cereal crops causes losses in yield and quality because of preharvest sprouting.
( Lawrenson et al., 2015 )

SDN1
CRISPR/Cas

Norwich Research Park, UK
Murdoch University, Australia

Plant development. Phenotypes consistent with increased GA response: tall and slender with light green vegetation.
(Lor et al., 2014)

SDN1
TALENs

University of Minnesota, USA
Hebrew University of Jerusalem, Israel

Semi-dwarf phenotype to improve lodging resistance and increased seed dormancy. Increased seed dormancy can be beneficial for use in the malting industry.
( Cheng et al., 2023 )

SDN1
CRISPR/Cas

University of Tasmania
Murdoch University
Department of Primary Industries and Regional Development, Australia
Chinese Academy of Agricultural Sciences, China

Increase in plant height, tiller number, grain protein content and yield. 1.5- to 2.8-fold increase in total chlorophyll content in the flag leaf at the grain filling stage. Delayed senescence by 10–14 days. High nitrogen content in shoots under low nitrogen conditions.
( Karunarathne et al., 2022 )

SDN1
CRISPR/Cas

Murdoch University
Department of Primary Industries and Regional Development, Australia

Traits related to industrial utilization

Conversion of hulled into naked barley.
( Gasparis et al., 2018 )

SDN1
CRISPR/Cas

National Research Institute
Warsaw University of Life Sciences (SGGW), Poland

Generation of male-sterile hexaploid wheat lines for use in hybrid seed production. The development and adoption of hybrid seed technology have led to dramatic increases in agricultural productivity.
( Okada et al., 2019 )

SDN1
CRISPR/Cas

The University of Adelaide, Australia
Huaiyin Normal University, China

Traits related to herbicide tolerance

Herbicide glyphosate tolerance.
( Arndell et al., 2019 )

SDN1
CRISPR/Cas

CSIRO
New South Wales Department of Primary Industries
The University of Adelaide, Australia

Imazethapyr, imazapic
( Wang et al., 2020 )

SDN1
CRISPR/Cas

Jiangsu Academy of Agricultural Sciences/Nanjing Branch of Chinese National Center for Rice Improvement
Yangzhou University
Jiangsu University, China
CSIRO Agriculture and Food, Australia

Herbicide tolerance (ALS-targeting)
( Wang et al., 2020 )

SDN1
CRISPR/Cas

Jiangsu Academy of Agricultural Sciences/Nanjing Branch of Chinese National Center for Rice Improvement
Yangzhou University
Jiangsu Academy of Agricultural Sciences
Jiangsu University, China
CSIRO Agriculture and Food, Australia

Traits related to product color/flavour

Albino phenotype.
( Syombua et al., 2021 )

SDN1
CRISPR/Cas

International Institute of Tropical Agriculture (IITA)
University of Nairobi, Kenya
University of Missouri
Iowa State University
Donald Danforth Plant Science Center, USA

Color modification due to reduced anthocyanin accumulation.
( Klimek-Chodacka et al., 2018 )

SDN1
CRISPR/Cas

University of Agriculture in Krakow, Poland
East Carolina University
University of Maryland, USA

Albinism and dwarfing.
( Naim et al., 2018 )

SDN1
CRISPR/Cas

Queensland University of Technology, Australia

Yellow and orange fruit color.
( Dahan-Meir et al., 2018 )

SDN2
CRISPR/Cas

Weizmann Institute of Science, Israel

Colour modification. Purple tomatoes.
( Cermak et al., 2015 )

SDN2
TALENs

University of Minnesota, USA
Academy of Sciences of the Czech Republic, Czech Republic

Fruit color: tangerine
(Ben Shlush et al., 2021)

SDN2
CRISPR/Cas

The Weizmann Institute of Science, Israel

Colour modification. Purple tomatoes.
( Cermak et al., 2015 )

SDN2
CRISPR/Cas

University of Minnesota, USA
Academy of Sciences of the Czech Republic, Czech Republic

Traits related to storage performance

Extended root shelf-life, which decreases its wastage.
( Mukami et al., 2023 )

SDN1
CRISPR/Cas

Kenyatta University
Jomo Kenyatta University of Agriculture Technology
Pwani University Kilifi, Kenya

Traits categories

Genome Editing Technique

Countries

Plant

Sdn Type

Traits related to biotic stress tolerance

Traits related to abiotic stress tolerance

Traits related to improved food/feed quality

Traits related to increased plant yield and growth

Traits related to industrial utilization

Traits related to herbicide tolerance

Traits related to product color/flavour

Traits related to storage performance