genome search | EU-SAGE

Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 73 results

Traits related to abiotic stress tolerance

Drought and salt tolerance.
( Curtin et al., 2018 )

SDN1
CRISPR/Cas

University of Minnesota, USA
The University of Newcastle, Australia

Broad-spectrum stress tolerance: enhanced low temperature, salinity, Pseudoperonospora cubensis and water-deficit tolerance.
(Dong et al., 2023)

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China
University of California, USA

Increased root length, which can restore good performance under water stress.
( Gabay et al., 2023 )

SDN1
CRISPR/Cas

University of California
Howard Hughes Medical Institute, USA
University of Haifa, Israel
Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET)
Universidad Nacional de San Martín (UNSAM), Argentina
Fudan University
China Agricultural University, China
Karolinska Institutet, Sweden

Increased drought tolerance.
( Abdallah et al., 2022 )

SDN1
CRISPR/Cas

Cairo University, Egypt
Crop Improvement and Genetics Unit, USA

Drought tolerance.
( Kim D et al,. 2018 )

SDN1
CRISPR/Cas

Montana State University, USA

Improved salinity tolerance.
( Wang et al., 2022 )

SDN1
CRISPR/Cas

National Taiwan University, Taiwan
University of North Carolina, USA

Reduced stomatal density. Intrinsic water-use efficiency was significantly impacted under both well-watered and drought conditions, making reduced stomatal density as a preferable trait.
( Clemens et al., 2022 )

SDN1
CRISPR/Cas

University of California
San Diego State University, USA

Modulate aluminium resistance. Aluminum (Al) toxicity is the main factor inhibiting plant root development and reducing crops yield in acidic soils.
( Zhang et al., 2022 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Academy of Agricultural and Forestry Sciences
China Agricultural University, China
University of California, USA

Traits related to increased plant yield and growth

Increased grain size and modulated shoot architecture.
( Miao et al., 2020 )

SDN1
CRISPR/Cas

Zhejiang A&
F University
Nanchang University
Chinese Academy of Sciences, China
Purdue University, USA

Shortened plant architecture and jointless pedicel without affecting the yield. This plant architecture can allow ground cultivation systems that do not require the support of stakes and ties and could be ultimately suitable for once-over mechanical harvesting.
( Lee et al., 2022 )

SDN1
CRISPR/Cas

University of Florida, USA

High temperature germination. Large increases in the maximum temperature for seed germination to allow for the cultivation of the crop in production areas with higher temperature.
( Bertier et al., 2018 )

SDN1
CRISPR/Cas

University of California, USA

Enhancing grain-yield-related traits by increases in meristem size
( Liu et al., 2021 )

SDN1
CRISPR/Cas

Cold Spring Harbor
University of Massachusetts Amherst, USA

Customize tomato cultivars for urban agriculture: increased compactness and decreased growth cycle of tomato plants.
(Kwon et al., 2020)

SDN1
CRISPR/Cas

Cold Spring Harbor Laboratory
Cornell University
University of Florida, USA
Wonkwang University, South Korea
Weizmann Institute of Science, Israel

Increased grain weight and grain size. Carbohydrate and total protein levels also increased.
( Guo et al., 2021 )

SDN1
CRISPR/Cas

Sichuan Agricultural University, China
University of California, USA

Positive regulation for grain dormancy. Lack of grain dormancy in cereal crops causes losses in yield and quality because of preharvest sprouting.
( Lawrenson et al., 2015 )

SDN1
CRISPR/Cas

Norwich Research Park, UK
Murdoch University, Australia

Early flowering and maturity. Flowering time (heading date) is an important trait for crop yield and cultivation.
( Wang et al., 2020 )

SDN1
CRISPR/Cas

Sinobioway Bio-Agriculture Group, Co., China
Corteva™ Agriscience, USA

Early flowering. Day-light sensitivity limited the geographical range of cultivation.
( Soyk et al., 2016 )

SDN1
CRISPR/Cas

Cold Spring Harbor Laboratory, USA
Max Planck Institute for Plant Breeding Research, Germany
Université Paris-Scalay, France

Promoted rice growth and productivity.
( Miao et al., 2018 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences, China
Purdue University, USA

Enhanced grain yield and semi-dwarf phenotype by manipulating brassinosteroid signal pathway.
( Song et al., 2023 )

SDN1
CRISPR/Cas

China Agricultural University, China
Hard Winter Wheat Genetics Research Unit, USA

Increased total kernel number or kernel weight.
( Kelliher et al., 2019 )

SDN1
CRISPR/Cas

Research Triangle Park
University of Georgia, USA
Syngenta Crop Protection, The Netherlands

Semi-dwarf phenotype and compact architecture to increase yield. Plant height and branch angle are the major architectural factors determining yield.
( Fan et al., 2021 )

SDN1
CRISPR/Cas

Ministry of Agriculture and Rural Affairs, China
Wilkes University, USA

Haploid induction to accelerate breeding in crop plants.
( Kelliher et al., 2017 )

SDN1
TALENs

Syngenta Seeds, USA

Combine agronomically desirable traits with useful traits present in wild lines. Threefold increase in fruit size and a tenfold increase in fruit number. Fruit lycopene accumulation is improved by 500% compared with the widely cultivated S. lycopersicum.
( Zsögön et al., 2018 )

SDN1
CRISPR/Cas

Universidade Federal de Viçosa
Universidade de São Paulo Paulo, Brazil
University of Minnesota, USA
Universität Münster, Germany

Rapid improvement of domestication traits and genes that control plant architecture, flower production and fruit size. Major productivity traits are improved in an orphan crop.
( Lemmon et al., 2018 )

SDN1
CRISPR/Cas

Cold Spring Harbor
The Boyce Thompson Institute
Cornell University, USA

Increased yield under different environmental conditions: well-watered, drought, normal nitrogen and low nitrogen field conditions and at multiple geographical locations.
(Wang et al., 2020)

SDN1
CRISPR/Cas

Sinobioway Bio-Agriculture Group Co.
Ltd
Corteva Agriscience
Johnston, USA

Bigger seedlings.
( Lor et al., 2014 )

SDN1
TALENs

University of Minnesota, USA

Increased yield.
( Zhou et al., 2019 )

SDN1
CRISPR/Cas

University of Electronic Science and Technology of China
Xichang University, China
University of Maryland, USA

Conferred lodging resistance. Tef is a staple food, and valuable cash crop in Ethiopia. Lodging is a major limitation to its production.
( Beyene et al., 2022 )

SDN1
CRISPR/Cas

Donald Danforth Plant Science Center
Corteva Agriscience
Michigan State University, USA
Ethiopian Institute of Agricultural Research, Ethiopia

Improve plant architecture to increase yield. Plant height and branch number are directly correlated with yield.
( Zheng et al., 2020 )

SDN1
CRISPR/Cas

Ministry of Agriculture, China
Wilkes University, USA

Improve biomass yield and salinity tolerance.
( Guan et al., 2020 )

SDN1
CRISPR/Cas

China Agricultural University
Shandong institute of agricultural sustainable development
Beijing Sure Academy of Biosciences, China
Oklahoma State University, USA

Increase in floral organ number or fruit size, conferring enhanced tomato fruit yield.
( Rodriguez-Leal et al., 2017 )

SDN1
CRISPR/Cas

Cold Spring Harbor Laboratory
University of Massachusetts Amherst, USA

Dwarf phenotype.
( Lawrenson et al., 2015 )

SDN1
CRISPR/Cas

Norwich Research Park, UK
Murdoch University, USA

Early flowering under long day conditions of higher latitudes to spread production of maize over a broad range of latitudes rapidly.
( Huang et al., 2018 )

SDN1
CRISPR/Cas

University of Wisconsin, USA

Improved nitrogen use efficiency.
( Li et al., 2018 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Huazhong Agricultural University, China
University of California, USA

Increased bending strength. Stalk lodging, which is generally determined by stalk strength, results in considerable yield loss and has become a primary threat to maize yield under high-density planting.
( Zhang et al., 2020 )

SDN1
CRISPR/Cas

China Agricultural University, China
Iowa State University, USA

Increases size of starch granules. Granule size is a key parameter for industrial processing. Larger granules may increase yield during processing and it has been shown in sweet potato that smaller starch granules degrade faster than large granules, so larger granule tubers may be beneficial for storage.
( Pfotenhauer et al., 2023 )

SDN1
CRISPR/Cas

University of Tennessee, USA

Altered tree architecture, exhibited pleiotropic phenotypes: including differences in branch angle and stem growth.
(Dutt et al., 2022)

SDN1
CRISPR/Cas

University of Florida, USA
Mansoura University, Egypt

Semi-dwarf phenotype. High varieties are challenged by weak lodging and damages caused by storms, dwarf varieties are suitable for mechanized plant maintenance and fruit harvesting.
( Shao et al., 2020 )

SDN1
CRISPR/Cas

Guangdong Academy of Agricultural Sciences
Hunan Agricultural University
Chinese Academy of Sciences
University of Chinese Academy of Sciences, China
University of Florida, USA

Semi-dwarf phenotype to improve lodging resistance and increased seed dormancy. Increased seed dormancy can be beneficial for use in the malting industry.
( Cheng et al., 2023 )

SDN1
CRISPR/Cas

University of Tasmania
Murdoch University
Department of Primary Industries and Regional Development, Australia
Chinese Academy of Agricultural Sciences, China

Bushy phenotype and increased tiller production.
( Liu et al., 2017 )

SDN1
CRISPR/Cas

Iowa State University, USA

Plant development. Phenotypes consistent with increased GA response: tall and slender with light green vegetation.
(Lor et al., 2014)

SDN1
TALENs

University of Minnesota, USA
Hebrew University of Jerusalem, Israel

Dwarf phenotype. Tomatoes with compact growth habits and reduced plant height can be useful in some environments.
( Tomlinson et al., 2019 )

SDN1
CRISPR/Cas

Norwich Research Park, UK
University of Minnesota, USA

Altered branch and petiole angles.
( Kangben et al., 2023 )

SDN1
CRISPR/Cas

Clemson University
HudsonAlpha Institute for Biotechnology
United States Department of Agriculture (USDA)
Cotton incorporated, USA

Increased grain yield under field drought stress conditions and no yield loss under well-watered conditions.
( Shi et al., 2017 )

SDN1
CRISPR/Cas

DuPont Pioneer, USA

Improved field performance: higher yield, producing on average 5.5 bushels per acre more. Waxy corn.
(Gao et al., 2020)

SDN1
CRISPR/Cas

Corteva Agriscience, USA

Increased plant yield due to architectural changes. Leaf inclination: maize plants with upright leaves can be planted at higher densities without shading.
(Brekke et al., 2011)

SDN1
CRISPR/Cas

Iowa State University, USA

Enhanced photosynthesis.
( Caddell et al., 2023 )

SDN1
CRISPR/Cas

United States Department of Agriculture - Agricultural Research Service (USDA ARS)
University of California at Berkeley
Utah State University
Texas A&
M University, USA

Altering leaf inclination angle which has the potential to elevate yield in high-density plantings.
( Brant et al., 2022 )

SDN1
CRISPR/Cas

University of Florida
DOE Center for Advanced Bioenergy and Bioproducts Innovation, USA
Kastamonu University, Turkey

Increased fruit size. Highly branched inflorescence and formation of multiple flowers.
( Rodriguez-Leal et al., 2017 )

SDN1
CRISPR/Cas

Cold Spring Harbor Laboratory
University of Massachusetts Amherst, USA

Increase in plant height, tiller number, grain protein content and yield. 1.5- to 2.8-fold increase in total chlorophyll content in the flag leaf at the grain filling stage. Delayed senescence by 10–14 days. High nitrogen content in shoots under low nitrogen conditions.
( Karunarathne et al., 2022 )

SDN1
CRISPR/Cas

Murdoch University
Department of Primary Industries and Regional Development, Australia

Improved high-density yield and drought/osmotic stress tolerance.
( Chen et al., 2020 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Shanxi Academy of Agricultural Sciences, China
Texas Tech University, USA

Faster seedling growth.
( Zhou et al., 2018 )

SDN1
CRISPR/Cas

University of Maryland, USA

Traits related to industrial utilization

Bio-fuel production: Reduced lignin content and improved sugar release.
(Park et al., 2017)

SDN1
CRISPR/Cas

Noble Research Institute, USA

Bioethanol production: Improved saccharification efficiency without compromising biomass yield.
(Kannan et al., 2017)

SDN1
TALENs

University of Florida
Novozymes North America Inc, USA
Korea Institute of Science and Technology (KIST), South Korea

Stem wood discoloration due to lignin reduction.
( Zhou et al., 2015 )

SDN1
CRISPR/Cas

University of Georgia, USA

Bio-fuel production: Reduced lignin content, improves cell wall composition for production of bio-ethanol.
(Jung et al., 2016)

SDN1
TALENs

Korea University, South Korea
University of Florida, USA

Asexual propagation trough seeds. Induction of apomeiosis, mitosis instead of meiosis. This proces leads to the production of genetically identical seeds, serving many applications in plant breeding.
( Khanday et al., 2019 )

SDN1
CRISPR/Cas

University of California
Innovative Genomics Institute
Iowa State University, USA
Université Paris-Saclay, France

Male sterility.
( Djukanovic et al., 2013 )

I-CreI

DuPont/Pioneer Agricultural Biotechnology
Precision Biosciences, USA

Enhanced biological nitrogen fixation to reduce the use of inorganic nitrogen fertilizers. Enhanced biofilm formation of soil diazotrophic bacteria by modified root microbiome structure.
( Yan et al., 2022 )

SDN1
CRISPR/Cas

University of California
Bayer Crop Science, USA

Trait stacking. Modern agriculture demands crops carrying multiple traits.
( Ainley et al., 2013 )

SDN1
ZFN

Dow AgroSciences LLC
Sangamo BioSciences, Inc., USA

Modified wood composition with traits desirable for fiber pulping and lower carbon emissions. The edited wood could bring efficiencies, bioeconomic opportunities and environmental benefits.
( Sulis et al., 2023 )

SDN1
CRISPR/Cas

North Carolina State University
University of Illinois at Urbana-Champaign, USA
Beihua University
Northeast Forestry University, China

Generation of male-sterile hexaploid wheat lines for use in hybrid seed production. The development and adoption of hybrid seed technology have led to dramatic increases in agricultural productivity.
( Okada et al., 2019 )

SDN1
CRISPR/Cas

The University of Adelaide, Australia
Huaiyin Normal University, China

Generating male sterility lines (MLS). Using MLS in hybrid seed production for monoclinous crops reduces costs and ensures high purity of the varieties because it does not produce pollen and has exserted stigmas.
( Svitashev et al., 2015 )

SDN1
CRISPR/Cas

DuPont Pioneer, USA

Induction of haploid plants and a reduced seed set for rice breeding.
( Yao et al., 2018 )

SDN2
CRISPR/Cas

ZhongGuanCun Life Science Park, China
Syngenta India Limited
Technology Centre
Medchal Mandal, India
Syngenta Crop Protection
LLC
Research Triangle Park, USA

Enhanced oil accumulation in the seed.
( Cai et al., 2024 )

SDN1
CRISPR/Cas

Brookhaven National Laboratory
Stony Brook University
Montana State University, USA

Accelerated abscission. Plant organ abscission is a process important for development and reproductive success,
( Liu et al., 2022 )

SDN1
CRISPR/Cas

Shenyang Agricultural University
Key Laboratory of Protected Horticulture of Ministry of Education, China
University of California at Davis
Crops Pathology and Genetic Research Unit, USA

Hairy root transformation. Hairy roots play a role in multiple processes, ranging from recombinant protein production and metabolic engineering to analyses of rhizosphere physiology and biochemistry.
( Ron et al., 2014 )

SDN1
CRISPR/Cas

University of California
Emory University, USA
University of Cambridge, UK

Rapid generation of male sterile (MS) bread wheat. MS is an important tool in creating hybrid crop varieties that provide a yield advantage over traditional varieties by harnessing heterosis.
( Singh et al., 2021 )

SDN1
CRISPR/Cas

DuPont Pioneer, USA

Generate self-compatible diploid potato lines for the application of efficient breeding methods.
( Enciso-Rodriguez et al., 2021 )

SDN1
CRISPR/Cas

Michigan State University, USA

Rubber biosynthesis. To accelerate the domestication of Taraxacum kok-saghyz (TK), a plant notable for its ability to produce high molecular weight rubber in its roots and which might be an alternative source of natural rubber.
( Iaffaldano et al., 2016 )

SDN1
CRISPR/Cas

Ohio Agricultural Research and Development Center, USA

Reduced lignin content and S (syringyl lignin)/G (guaiacyl lignin) (S/G) ratio alteration to reduce cell wall recalcitrance and improve bioethanol production. Lignin is a major component of secondary cell walls and contributes to the recalcitrance problem during fermentation.
( Park et al., 2021 )

SDN1
CRISPR/Cas

The Samuel Roberts Noble Foundation
BioEnergy Science Center
University of Tennessee, USA

Accumulate low levels of alkaloids. Nicotine is the most abundant alkaloid produced in tobacco plants. Switching to cigarettes containing levels of nicotine below the level of sustaining an addiction response will smoke less and/or find it easier to quit. Possibly, the US Food and Drug Administration (FDA) may mandate such reductions in future cigarette products.
( Smith et al., 2022 )

SDN1
CRISPR/Cas

North Carolina State University, USA

Complete reproductive sterility to prevent the spread of highly domesticated, exotic or genetically modified organisms into wild populations.
( Azeez et al., 2021 )

SDN1
CRISPR/Cas

Michigan Technological University, USA

Traits categories

Genome Editing Technique

Countries

Plant

Sdn Type

Traits related to abiotic stress tolerance

Traits related to increased plant yield and growth

Traits related to industrial utilization