Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Genome Editing Technique

Plant

Displaying 80 results

Traits related to biotic stress tolerance

Fungal resistance: strong resistance against Fusarium oxysporum f. sp. lycopersici (Fol), which causes Fusarium Wilt Disease in tomato.
(Debbarma et al., 2023)
SDN1
CRISPR/Cas
CSIR-North East Institute of Science and Technology
Academy of Scientific and Innovative Research
Assam Agricultural University
Central Muga Eri Research and Training Institute
International Crop Research Institute for the Semi Arid Tropics, India
Bacterial resistance: Strong resistance to Xanthomonas oryzae, causing bacterial blight, a devastating rice disease resulting in yield losses.
(Li et al., 2012)
SDN1
TALENs
Iowa State University, USA
Effective detection of a resistance-breaking strain of tomato spotted wilt virus (TSWV). TSWV causes a great threat to various food crops globally and can cause devastating epidemics.
( Shymanovich et al., 2024 )
SDN1
CRISPR/Cas
North Carolina State University, USA
Bacterial resistance: Enhanced resistance against hemibiotrophic pathogens M. oryzae and Xanthomonas oryzae pv. oryzae (but increased susceptibility to Cochliobolus miyabeanus)
(Kim et al., 2022)
SDN1
CRISPR/Cas
Seoul National University
Kyung Hee University, South Korea
Pennsylvania State University, USA
Fungal resistance: improved resistance to necrotrophic fungus Botrytis cinerea.
(Jeon et al., 2020)
SDN1
CRISPR/Cas
Stanford University, UK
L’Oreal, France
Howard Hughes Medical Institute, USA
Bacterial resistance: Resistance against African Xanthomonas oryzae isolates, causing agents of bacterial blight. Bacterial blight threatens rice populations in Asia and West Africa.
(Li et al., 2024)

BE
University of Missouri
Donald Danforth Plant Science Center, USA
Department of Nanjing Agricultural University, China
Bacterial resistance: Strong resistance to Xanthomonas oryzae, causing bacterial blight, a devastating rice disease resulting in yield losses.
(Zhou et al., 2015)
SDN1
CRISPR/Cas
Iowa State University, USA
Resistance to parasitic weed: Phelipanche aegyptiaca. The obligate root parasitic plant causes great damages to important crops and represents one of the most destructive and greatest challenges for the agricultural economy.
(Bari et al., 2019)
SDN1
CRISPR/Cas
Newe Ya’ar Research Center,
Agricultural Research Organization (ARO), Israel
University of California, USA
Fungal resistance: Decreased susceptibility against sheath blight disease caused by Rhizoctonia solani AGI-1A and is one of the three major rice diseases. Sheath blight disease can cause severe yield losses.
(Zhao et al., 2024)
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences
Hebei Agricultural University
Agricultural College of Yangzhou University, China
The Ohio State University, USA
Bacterial resistance: Strong resistance to Xanthomonas oryzae, causing bacterial blight, a devastating rice disease resulting in yield losses.
(Shan et al., 2013)
SDN1
TALENs
Chinese Academy of Sciences, University of Electronic Science and Technology of China, China
University of Minnesota, USA

Resistance to parasitic weed: Phelipanche aegyptiaca. The obligate root parasitic plant causes great damages to important crops and represents one of the most destructive and greatest challenges for the agricultural economy.
(Bari et al., 2021)
SDN1
CRISPR/Cas
Central University of Punjab, India
Newe Ya’ar Research Center
Agricultural Research Organization (ARO), Israel
Bacterial resistance: Plant moderately resistant against a strain of the gram-negative bacterium, Xanthomonas oryzae pv. oryzae (Xoo). Xoo severely impacts rice productivity by causing bacterial leaf blight disease.
(Bhagya Sree et al., 2023)
SDN1
CRISPR/Cas
Tamil Nadu Agricultural University, India
Bacterial resistance: resistance to different pathogens including Xanthomonas spp., P. syringae and P. capsici.
(de Toledo Thomazella et al., 2016)
SDN1
CRISPR/Cas
University of California, USA
Bacterial resistance: resistance against bacterial spot disease, caused by Xanthomonas species, which could be a devastating to tomato as well as pepper.
(Ortega et al., 2024)
SDN1
CRISPR/Cas
University of California
University of Florida, USA
Viral resistance: enhanced resistance against chickpea chlorotic dwarf virus (CpCDV). The range of symptoms caused by CpCDV varies from mosaic pattern to streaks to leaf curling and can include browning of the collar region and stunting, foliar chlorosis and necrosis.
(Munir Malik et al., 2022)
SDN1
CRISPR/Cas
University of the Punjab
University of Gujrat, Pakistan
Washington State University, USA
Broad-spectrum disease resistance without yield loss.
( Sha et al., 2023 )
SDN1
CRISPR/Cas
Huazhong Agricultural University
Chengdu Normal University
Jiangxi Academy of Agricultural Sciences
Anhui Agricultural University
BGI-Shenzhen
Northwest A&
F University
Shandong Academy of Agricultural Sciences, China
Université de Bordeaux, France
University of California
The Joint BioEnergy Institute, USA
University of Adelaide, Australia
Viral resistance: resistance to rice tungro disease (RTD), the most important viral disease that limits rice production.
(Kumam et al., 2022)
SDN1
CRISPR/Cas
Tamil Nadu Agricultural University
International Centre for Genetic Engineering and Biotechnology
ICAR-Indian Institute of Rice Research, India
Bacterial resistance: Strong resistance to Xanthomonas oryzae, causing bacterial blight, a devastating rice disease resulting in yield losses.
(Li et al., 2013)
SDN1
TALENs
Iowa State University, USA
Guangxi University, China
Pospiviroids detection method. Pospiviroids are a major production constraint.
( Zhai et al., 2024 )
SDN1
CRISPR/Cas
Washington State University
USDA-ARS, USA
Bacterial resistance: improved resistance to Xanthomonas oryzae, which causes bacterial blight, a devastating rice disease resulting in yield losses.
(Oliva et al., 2019)
SDN1
CRISPR/Cas
International Rice Research Institute, Philippines
University of Missouri
University of Florida
Iowa State University
Donald Danforth Plant Science Center, USA
Université Montpellier, France
Heinrich Heine Universität Düsseldorf
Max Planck Institute for Plant Breeding Research
Erfurt University of Applied Sciences, Germany
Nagoya University, Japan
Bacterial resistance: Resistance/moderately resistance against Bacterial leaf blight (BLB), caused by Xanthomonas oryzae pv oryzae (Xoo). BLB is a major constraint in rice production.
(Arulganesh et al., 2022)
SDN1
CRISPR/Cas
Tamil Nadu Agricultural University, India

Traits related to abiotic stress tolerance

Drought and salt tolerance.
( Kumar et al., 2020 )
SDN1
CRISPR/Cas
ICAR-Indian Agricultural Research Institute
Bhartidasan University, India
Improved salinity tolerance.
( Wang et al., 2022 )
SDN1
CRISPR/Cas
National Taiwan University, Taiwan
University of North Carolina, USA
Reduced arsenic content. Arsenic accumulation in rice poses a threat to human health.
( Singh et al., 2024 )
SDN1
CRISPR/Cas
Academy of Scientific and Innovative Research (AcSIR)
CSIR-National Botanical Research Institute
CSIR-National Botanical Research Institute, India
Modulate aluminium resistance. Aluminum (Al) toxicity is the main factor inhibiting plant root development and reducing crops yield in acidic soils.
( Zhang et al., 2022 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences
Academy of Agricultural and Forestry Sciences
China Agricultural University, China
University of California, USA

Traits related to improved food/feed quality

High fruit malate accumulation. Malate is a primary organic acid in tomato and a crucial compound that contributes to fruit flavor and palatability.
( Ye et al., 2017 )
SDN1
CRISPR/Cas
Huazhong Agricultural University, China
Cornell University, USA
Increased amylose content in the seeds, thus a lower Glycemic Index (GI) value. Low GI rice is preferred to avoid a sudden rise in glucose in the bloodstream. Starch with a high GI threatens healthy individuals to get diabetes type II and proves extremely harmful for existing diabetes type II patients.
( Jameel et al., 2022 )
SDN1
CRISPR/Cas
Jamia Millia Islamia
International Centre for Genetic Engineering and Biotechnology, India
King Saud University, Saudi Arabia
Slender grains in bold grain varieties.
( Shanthinie et al., 2024 )
SDN1
CRISPR/Cas
Tamil Nadu Agricultural University, India
Increased amylose content. Cereals high in amylose content (AC) and resistant starch (RS) offer potential health benefits and reduce risks of diseases such as coronary heart disease, diabetes and certain colon and rectum cancers.
( Sun et al., 2017 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences, China
University of California, USA
University of Liege, Belgium
Reduced grain chalkiness.
( Gann et al., 2023 )
SDN1
CRISPR/Cas
Cell and Molecular Biology Program
Department of Chemistry and Biochemistry
University of Arkansas at Little Rock, USA
Carotenoid-enriched. Carotenoids, the source of pro vitamin A, are an essential component of dietary antioxidants.
( Dong et al., 2020 )
SDN3
CRISPR/Cas
University of California
Innovative Genomics Institute
The Joint Bioenergy Institute, USA
Improve glutinosity in elite varieties. Decreased amylose content without affecting other desirable agronomic traits.
( Zhang et al., 2018 )
SDN1
CRISPR/Cas
Chinese Academy of Sciences, China
Purdue University
University of Queensland, USA
Fine-tuning the amylose content, one of the major contributors to the eating and cooking quality.
( Xu et al., 2021 )

BE
Jiangsu Academy of Agricultural Sciences/Nanjing Branch of Chinese National Center for Rice Improvement
Yangzhou University
Chinese Academy of Sciences, China
CSIRO Agriculture and Food, Australia
Increased RS. Cereals high in RS may be beneficial to improve human health and reduce the risk of diet-related chronic diseases.
( Biswas et al., 2022 )
SDN1
CRISPR/Cas
Texas A&
M Univ.
Avance Biosciences Inc., USA
High-quality sugar production by rice (98% sucrose content). Carbohydrates are an essential energy-source. Sugarcane and sugar beet were the only two crop plants used to produce sugar.
( Honma et al., 2020 )
SDN1
CRISPR/Cas
Fujian Agriculture and Forestry University, China
Faculty of Engineering
Kitami Institute of Technology
NagoyaUniversity
Tokyo Metropolitan University, Japan
Carnegie Institution for Science, USA
Large parthenocarpic fruits. Parthenocarpy, also known as seedless fruits, is preferred by consumers and it ensures consistent fruit yield in variable environmental conditions.
( Hu et al., 2023 )
SDN1
CRISPR/Cas
Duke University, USA
Improved aleurone layer with enhanced grain protein content. Improved grain nutritional quality by improved accumulation of essential dietary minerals (Fe, Zn, K, P, Ca) in the endosperm of rice grain. Improved root and shoot architecture.
( Achary et al., 2021 )
SDN1
CRISPR/Cas
International Centre for Genetic Engineering and Biotechnology, India
Low glutelin content in the rice germplasm: patients with chronic kidney disease (CKD) and phenylketonuria (PKU) need to eat rice with low glutelin content.
(Chen et al., 2022)
SDN1
CRISPR/Cas
Nanjing Branch of Chinese National Center for Rice Improvement
Yangzhou University
Henan Agricultural University
Jiangsu Academy of Agricultural Sciences, China
CSIRO Agriculture and Food, Australia
Increased grain weight and grain size. Carbohydrate and total protein levels also increased.
( Guo et al., 2021 )
SDN1
CRISPR/Cas
Sichuan Agricultural University, China
University of California, USA
Highly specific detection of Ochratoxin A (OTA) in cereal samples. OTA is classified as a Class 2B carcinogens. The method can be flexibly customized to detect a wide range of small molecular targets and holds great promise as a versatile sensing kit with applications in various fields requiring sensitive and specific detection of diverse analytes.
( Chen et al., 2023 )
SDN1
CRISPR/Cas
Ningbo University
Hainan University
Ningbo Clinical Pathology Diagnosis Center, China
University of New South Wales, Australia
Increased sugar and amino acid content leading to improved fruit quality.
( Nguyen et al., 2023 )
SDN1
CRISPR/Cas
Vietnam Academy of Science and Technology
Food Industries Research Institute, Vietnam
University of Missouri, USA
Fragrant rice. Introduction of aroma into any non-aromatic rice varieties.
( Ashokkumar et al., 2020 )
SDN1
CRISPR/Cas
Tamil Nadu Agricultural University, India

Traits related to increased plant yield and growth

Bigger seedlings.
( Lor et al., 2014 )
SDN1
TALENs
University of Minnesota, USA
Dwarf phenotype. Tomatoes with compact growth habits and reduced plant height can be useful in some environments.
( Tomlinson et al., 2019 )
SDN1
CRISPR/Cas
Norwich Research Park, UK
University of Minnesota, USA
Combine agronomically desirable traits with useful traits present in wild lines. Threefold increase in fruit size and a tenfold increase in fruit number. Fruit lycopene accumulation is improved by 500% compared with the widely cultivated S. lycopersicum.
( Zsögön et al., 2018 )
SDN1
CRISPR/Cas
Universidade Federal de Viçosa
Universidade de São Paulo Paulo, Brazil
University of Minnesota, USA
Universität Münster, Germany
Improved nitrogen use efficiency.
( Li et al., 2018 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences
Huazhong Agricultural University, China
University of California, USA
Increased grain size and modulated shoot architecture.
( Miao et al., 2020 )
SDN1
CRISPR/Cas
Zhejiang A&
F University
Nanchang University
Chinese Academy of Sciences, China
Purdue University, USA
Delayed onset of ripening.
( Nizampatnam et al., 2023 )
SDN1
CRISPR/Cas
University of Hyderabad
SRM University-AP, India
Enhanced photosynthesis.
( Caddell et al., 2023 )
SDN1
CRISPR/Cas
United States Department of Agriculture - Agricultural Research Service (USDA ARS)
University of California at Berkeley
Utah State University
Texas A&
M University, USA
Increase in floral organ number or fruit size, conferring enhanced tomato fruit yield.
( Rodriguez-Leal et al., 2017 )
SDN1
CRISPR/Cas
Cold Spring Harbor Laboratory
University of Massachusetts Amherst, USA
Control grain size and seed coat color.
( Tra et al., 2021 )

BE
International Rice Research Institute, Philippines
Dahlem Center of Plant Sciences Freie Universität, Germany
Synthetic Biology, Biofuel and Genome Editing R&
D Reliance Industries Ltd, India
Early flowering and maturity. Flowering time (heading date) is an important trait for crop yield and cultivation.
( Wang et al., 2020 )
SDN1
CRISPR/Cas
Sinobioway Bio-Agriculture Group, Co., China
Corteva™ Agriscience, USA
Promoted rice growth and productivity.
( Miao et al., 2018 )
SDN1
CRISPR/Cas
Chinese Academy of Sciences, China
Purdue University, USA
Plant development. Phenotypes consistent with increased GA response: tall and slender with light green vegetation.
(Lor et al., 2014)
SDN1
TALENs
University of Minnesota, USA
Hebrew University of Jerusalem, Israel
Increased yield under different environmental conditions: well-watered, drought, normal nitrogen and low nitrogen field conditions and at multiple geographical locations.
(Wang et al., 2020)
SDN1
CRISPR/Cas
Sinobioway Bio-Agriculture Group Co.
Ltd
Corteva Agriscience
Johnston, USA
Increased yield.
( Zhou et al., 2019 )
SDN1
CRISPR/Cas
University of Electronic Science and Technology of China
Xichang University, China
University of Maryland, USA
Increased stomatal density, stomatal conductance, photosynthetic rate and transpiration rate. Fine tuning the stomatal traits can enhance climate resilience in crops.
( Rathnasamy et al., 2023 )
SDN1
CRISPR/Cas
Tamil Nadu Agricultural University
Sugarcane Breeding Institute, India
Early flowering. Day-light sensitivity limited the geographical range of cultivation.
( Soyk et al., 2016 )
SDN1
CRISPR/Cas
Cold Spring Harbor Laboratory, USA
Max Planck Institute for Plant Breeding Research, Germany
Université Paris-Scalay, France
Shortened plant architecture and jointless pedicel without affecting the yield. This plant architecture can allow ground cultivation systems that do not require the support of stakes and ties and could be ultimately suitable for once-over mechanical harvesting.
( Lee et al., 2022 )
SDN1
CRISPR/Cas
University of Florida, USA
Increased fruit size. Highly branched inflorescence and formation of multiple flowers.
( Rodri­guez-Leal et al., 2017 )
SDN1
CRISPR/Cas
Cold Spring Harbor Laboratory
University of Massachusetts Amherst, USA
Customize tomato cultivars for urban agriculture: increased compactness and decreased growth cycle of tomato plants.
(Kwon et al., 2020)
SDN1
CRISPR/Cas
Cold Spring Harbor Laboratory
Cornell University
University of Florida, USA
Wonkwang University, South Korea
Weizmann Institute of Science, Israel

Traits related to industrial utilization

Accelerated abscission. Plant organ abscission is a process important for development and reproductive success,
( Liu et al., 2022 )
SDN1
CRISPR/Cas
Shenyang Agricultural University
Key Laboratory of Protected Horticulture of Ministry of Education, China
University of California at Davis
Crops Pathology and Genetic Research Unit, USA
Asexual propagation trough seeds. Induction of apomeiosis, mitosis instead of meiosis. This proces leads to the production of genetically identical seeds, serving many applications in plant breeding.
( Khanday et al., 2019 )
SDN1
CRISPR/Cas
University of California
Innovative Genomics Institute
Iowa State University, USA
Université Paris-Saclay, France
Genetic variability. The genetically reprogrammed rice plants can act as donor lines to stabilize important agronomic traits or can be a potential resource to create more segregating population.
( K et al., 2021 )
SDN1
CRISPR/Cas
University of Agricultural Sciences
Regional Centre for Biotechnology, India
Induction of haploid plants and a reduced seed set for rice breeding.
( Yao et al., 2018 )
SDN2
CRISPR/Cas
ZhongGuanCun Life Science Park, China
Syngenta India Limited
Technology Centre
Medchal Mandal, India
Syngenta Crop Protection
LLC
Research Triangle Park, USA
Hairy root transformation. Hairy roots play a role in multiple processes, ranging from recombinant protein production and metabolic engineering to analyses of rhizosphere physiology and biochemistry.
( Ron et al., 2014 )
SDN1
CRISPR/Cas
University of California
Emory University, USA
University of Cambridge, UK
Enhanced biological nitrogen fixation to reduce the use of inorganic nitrogen fertilizers. Enhanced biofilm formation of soil diazotrophic bacteria by modified root microbiome structure.
( Yan et al., 2022 )
SDN1
CRISPR/Cas
University of California
Bayer Crop Science, USA

Traits related to herbicide tolerance

Imazethapyr, imazapic
( Wang et al., 2020 )
SDN1
CRISPR/Cas
Jiangsu Academy of Agricultural Sciences/Nanjing Branch of Chinese National Center for Rice Improvement
Yangzhou University
Jiangsu University, China
CSIRO Agriculture and Food, Australia
Herbicide tolerance (ALS-targeting)
( Wang et al., 2020 )
SDN1
CRISPR/Cas
Jiangsu Academy of Agricultural Sciences/Nanjing Branch of Chinese National Center for Rice Improvement
Yangzhou University
Jiangsu Academy of Agricultural Sciences
Jiangsu University, China
CSIRO Agriculture and Food, Australia
Bispyribac sodium
( Butt et al., 2017 )
SDN2
CRISPR/Cas
King Abdullah University of Science and Technology, Saudi Arabia
Agricultural Research Center, Egypt
Rice University, USA
Herbicide resistance.
( Li et al., 2016 )
SDN2
TALENs
Iowa State University, USA
Chlorsulfuron resistance.
( Huang et al., 2023 )

BE
University of Florida, USA

Traits related to product color/flavour

Colour modification. Purple tomatoes.
( Cermak et al., 2015 )
SDN2
TALENs
University of Minnesota, USA
Academy of Sciences of the Czech Republic, Czech Republic
Colour modification. Purple tomatoes.
( Cermak et al., 2015 )
SDN2
CRISPR/Cas
University of Minnesota, USA
Academy of Sciences of the Czech Republic, Czech Republic
Increased content of phenylacetaldehyde, sucrose and fructose, which are major contributors to flavor in many foods, including tomato.
( Li et al., 2023 )
SDN1
CRISPR/Cas
University of Florida, USA
Max-Planck-Institute of Molecular Plant Physiology, Germany

Traits related to storage performance

Delayed fruit ripening.
( Lang et al., 2017 )
SDN1
CRISPR/Cas
Chinese Academy of Sciences, China
Purdue University, USA
Improved shelf-life by targeting the genes modulating pectin degradation in ripening tomato.
( Wang et al., 2019 )
SDN1
CRISPR/Cas
University of London
University of Leicester
University of Nottingham
University of Leeds, UK
International Islamic University Malaysia, Malaysia
Shanxi Academy of Agricultural Sciences, China
University of California, USA
Improved shelf-life with improved or not affected sugar: acid ratio, aroma volatiles, and skin color.
(Ortega-Salazar et al., 2023)
SDN1
CRISPR/Cas
University of California, USA
Zhejiang Normal University, China
University of Nottingham, UK
Controlling the rate of fruit softening to extend shelf life.
( Uluisik et al., 2016 )
SDN1
CRISPR/Cas
University of Nottingham
Royal Holloway University of London
Heygates Ltd
Syngenta Seeds
Sutton Bonington Campus, UK
Syngenta Crop Protection
University of California
Cornell University
Skidmore College, USA
Delayed fruit ripening.
( Li et al., 2022 )
SDN1
CRISPR/Cas
Nanjing Agricultural University, China
University of Connecticut, USA