genome search | EU-SAGE

Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 322 results

Traits related to biotic stress tolerance

Visual detection of Fusarium temperatum, the causal agent of maize stalk rot disease which reduces grain yield and threatens food safety and quality.
This simple detection platform allows high-throughput testing with potential for applications in field detection.
( Li et al., 2023 )

SDN1
CRISPR/Cas

Jilin University
Jilin Agricultural University
Shenzhen Campus of Sun Yat-sen University, China

Viral resistance: Partial resistance to rice black-streaked dwarf virus (RBSDV). RBSDV is a serious threat in Chinese rice production.
(Wang et al., 2021)

SDN1
CRISPR/Cas

Jiangsu Academy of Agricultural Sciences
Nanjing Agricultural University, China

Sensitive and specific visual detection method for Acidovorax citrulli, an important seed-borne disease of the cucurbits.
( Wang et al., 2024 )

SDN1
CRISPR/Cas

Fuyang Normal University
Anhui Jianzhu University
Southern Subtropicals Grops Research Institute, China

Viral resistance: Attenuated infection symptoms and reduced viral RNA accumulation, specific for the cucumber mosaic virus (CMV) or tobacco mosaic virus (TMV).
(Zhang et al., 2018)

SDN1
CRISPR/Cas

South China Agricultural University, China
University of Missouri, USA

Bacterial resistance: Strong resistance to Xanthomonas oryzae, causing bacterial blight, a devastating rice disease.
(Li et al., 2020)

SDN1
CRISPR/Cas

College of Life Science and Technology &
College of Horticulture &
Forestry Sciences
Huazhong Agricultural University, China

Fungal resistance: broad-spectrum resistance to rice pathogens without adverse effects in terms of growth and yield.
(Chen et al., 2023)

SDN1
CRISPR/Cas

Anhui Agricultural University
Huazhong Agricultural University, China

Disease-resistant and fertile varieties.
( Li et al., 2022 )

SDN1
CRISPR/Cas

Hubei Academy of Agricultural Sciences
Huazhong Agricultural University

Hubei Hongshan Laborator, China

Fast and accurate field screening and differentiation of four major Tobamoviruses infecting tomato and pepper. Tomatoviruses are the most important viruses infecting plants and cause huge economic losses to tomato and pepper crops globally.
( Zhao et al., 2023 )

SDN1
CRISPR/Cas

Chinese Academy of Inspection and Quarantine
China Agricultural University, China

Viral resistance: increased resistance against wheat yellow mosaic virus (WYMV) without yield penalty. WYMV results in severe yield losses in hexaploid wheat.
(Kan et al., 2023)

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences (CAAS)
Agricultural Sciences Institute in Jiangsu Lixiahe Area, China

Fungal resistance: Enhanced resistance to the pathogen Sclerotinia sclerotiorum.
(Sun et al., 2018)

SDN1
CRISPR/Cas

Yangzhou University, China

Fungal resistance: increased resistance against powdery mildew, a destructive disease that threatens cucumber production globally.
(Dong et al., 2023)

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China
University of California Davis, USA
Wageningen University &
Research, The Netherlands

Viral resistance: Resistance to Potato Virus Y (PVY), one of the most devastating viral pathogens causing substantial harvest losses.
(Zhan et al., 2019)

CRISPR/Cas

Hubei University
Huazhong Agricultural University, China
Max‐Planck‐Institut für Molekulare Pflanzenphysiologie, Germany

Bacterial resistance: Strong resistance to Xanthomonas oryzae, causing bacterial blight, a devastating rice disease resulting in yield losses.
(Li et al., 2013)

SDN1
TALENs

Iowa State University, USA
Guangxi University, China

Visual detection of maize chlorotic mottle virus (MCMV), one of the important quarantine pathogens in China. This novel method is specific, rapid, sensitive and does not require special instruments and technical expertise.
( Duan et al., 2022 )

SDN1
CRISPR/Cas

China Agricultural University
Yazhou Bay Science and Technology City, China
Alexandria University, Egypt

Fungal resistance: enhanced resistance against rust caused by Puccinia striiformis f. sp. tritici and powdery mildew caused by Blumeria graminis f. sp. tritici., while also increasing yield.
(Liu et al., 2024)

SDN1
CRISPR/Cas

Southwest University
Yangtze University, China
University of Cologne, Germany
University of Maryland

Enhanced blast disease resistance
( Liao et al., 2022 )

SDN1
CRISPR/Cas

Sichuan Agricultural University, China

Viral resistance: Strong barley yellow dwarf virusses (BYDV) resistance without negative effects on plant growth under field conditions. BYDV threatens efficient and stable production of wheat, maize, barley and oats.
(Wang et al., 2023)

SDN1
CRISPR/Cas

Henan Agricultural University
The Shennong Laboratory
Chinese Academy of Agricultural Sciences, China

Confered resistance to ear rot caused by Fusarium verticillioides.
( Liu et al., 2022 )

SDN1
CRISPR/Cas

National Key Facility for Crop Gene Resources and Genetic Improvement
Hainan Yazhou Bay Seed Lab, China

Fungal resistance: enhanced resistance to Golovinomyces cichoracearum, which causes powdery mildew.
(Wang et al., 2023)

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Linyi Tobacco Company
Tobacco Research Institute of Hubei Province
China Tobacco Hunan Industrial Co., China

Fungal resistance to Oidium neolycopersici, causing powdery mildew, one of the most important diseases limiting the production of wheat.
( Wang et al., 2014 )

SDN1
TALENs

Chinese Academy of Sciences, China

Reduced aphid damage to improve crop resistance to aphids or other insects. Restrict aphid sucking on watermelon.
( Li et al., 2021 )

SDN1
CRISPR/Cas

Beijing Academy of Agricultural and Forestry Sciences, China

Enhanced resistance against rice bacterial blight (BB) and bacterial leaf streak (BLS).
( Wang et al., 2024 )

SDN1
CRISPR/Cas

Zhejiang Normal University, China

Viral resistance: highly resistant to viral infection with beet severe curly top virus (BSCTV), a geminivirus that can cause serious damage to many crop plants.
(Ji et al., 2015)

SDN1
CRISPR/Cas

University of Chinese Academy of Sciences, China

Detection assay for brassica yellows virus (BrYV) detection. BrYV is an economically important virus threatening cruciferous species.
( Xu et al., 2024 )

SDN1
CRISPR/Cas

Guizhou University
Guizhou Academy of Tobacco Sciences
Guizhou Academy of Agricultural Sciences, China

Bacterial resistance: Strong resistance to Xanthomonas oryzae, causing bacterial blight, a devastating rice disease in Southeast Asia and West Africa.
(Wei et al., 2021)

SDN2
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China
Agricultural Research Center, Egypt

Visual detection of brassica yellows virus (BrYV), an economically important virus on cruciferous species. This assay allows for convenient, portable, rapid, low-cost, highly sensitive and specific detection and has great potential for on-site monitoring of BrYV.
( Xu et al., 2023 )

SDN1
CRISPR/Cas

Guizhou University, China

Robust rust resistance to pandemic stripe rust caused by Puccinia striiformis (Pst) without growth and yield penalty.
( Wang et al., 2022 )

SDN1
CRISPR/Cas

Northwest A&
F University
Chinese Academy of Sciences, China

Bacterial and fungal resistance: increased resistance against the bacterial pathogen Xanthomonas oryzae pv. oryzae (Xoo) and fungal pathogen Magnaporthe oryzae causing bacterial blight and rice blast, respectively.
(Liu et al., 2023)

SDN1
CRISPR/Cas

Hunan Agricultural University
Hunan Provincial Key Laboratory of Rice and Rapeseed Breeding for Disease Resistance
Hunan Academy of Agricultural Sciences
State Key Laboratory of Hybrid Rice, China

Fungal resistance: increased resistance to southern leaf blight (SLB), caused by the necrotrophic fungal pathogen Cochliobolus heterostrophus (anamorph Bipolaris maydis). SLB is a major foliar disease which causes significant yield losses in maize worldwide.
(Chen et al., 2023)

SDN1
CRISPR/Cas

Northwest A&
F University, China
Corteva AgriscienceTM
USDA-ARS
North Carolina State University, USA

Viral resistance: Reduced viral load and symptoms after bean yellow dwarf virus (BeYDV) infection.
(Baltes et al., 2015)

SDN1
CRISPR/Cas

University of Minnesota
The Ohio State University, USA
Institute of Biophysics ASCR, Czech Republic

Fungal and bacterial resistance: improved resistance against Magnaporthe oryzae–caused rice blast and bacterial leaf streak caused by Xanthomonas oryzae. Rice blast and bacterial leaf streak are deadly diseases that can lead to serious damage.
(Yang et al., 2023)

SDN1
CRISPR/Cas

Guangxi University
South China Agricultural University
Guangxi Lvhai
Seed Co., China

Fungal resistance: enhanced resistance to Phytophthora infestans. Phytophthora infestans causes late blight disease, which is severely damaging to the global tomato industry
(Hong et al., 2021)

SDN1
CRISPR/Cas

Dalian University of Technology
Beijing Academy of Agriculture &
Forestry Sciences
Shenyang Agricultural University/Key Laboratory of Protected Horticulture, China

Viral resistance: highly efficient resistance to a broad spectrum of geminiviruses. Geminiviruses severely damage economically important crops worldwide.
(Li et al., 2023)

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Guangxi University
Zhejiang University, China

Bacterial resistance: Xanthomonas citri, causing citrus canker, one of the most serious diseases affecting the global citrus industry. Citrus is the most produced fruit in the world.
(Peng et al., 2017)

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences and National Center for Citrus Variety Improvement
Southwest University, China

Bacterial resistance: Strong resistance to Xanthomonas oryzae, causing bacterial blight, a devastating rice disease resulting in yield losses.
(Zhou et al., 2018)

SDN1
CRISPR/Cas

National Center for Plant Gene Research
Sichuan Agricultural University, China

Increased jasmonic acid (JA) accumulation after wounding and plant resistance to herbivorous insects.
( Sun et al., 2021 )

SDN1
CRISPR/Cas

China Agricultural University, China

Viral resistance: Increased resistance to a potyvirus sugarcane mosaic virus, which causes dwarf mosaic disease in maize, sugarcane and sorghum.
(Xie et al., 2024)

SDN1
CRISPR/Cas

China Agricultural University
Longping Agriculture Science Co. Ltd.
Chinese Academy of Sciences
Yunnan Agricultural University, China

Viral resistance: resistance to potato virus Y (PVY), one of the most economically and scientifically important plant viruses, causing damaging diseases of cultivated tobacco around the world.
(Ruyi et al., 2021)

SDN1
CRISPR/Cas

Mudanjiang Teachers College
Jilin Normal University
Mudanjiang Tobacco Research Institute, China

Fungal resistance: broad-spectrum stress tolerance including Pseudoperonospora cubernsis (P. cubensis) resistance. P. cubensis is the causal agent of cucurbit downy mildew, responsible for devastating losses worldwide of cucumber, cantaloupe, pumpkin, watermelon and squash.
(Dong et al., 2023)

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China
University of California, USA

Enhanced resistance to powdery mildew.
( Wang et al., 2022 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences Institute of Tobacco Research, China

Fungal resistance: Fusarium oxysporum f.sp. niveum (FON), one of the most devastaging diseases affecting watermelons. FON progresses along xylem vessels, causing the hollow and dried-out stems.
(Zhang et al., 2020)

SDN1
CRISPR/Cas

Jiangsu Academy of Agricultural Sciences
Jiangsu Key Laboratory for Horticultural Crop Genetic Improvement, China

Enhanced resistance to insects, no serotonin production and higher salicylic acid levels. Rice brown planthopper (BPH; Nilaparvata lugens Stål) and striped stem borer (SSB; Chilo suppressalis) are the two most serious pests in rice production.
( Lu et al., 2018 )

SDN1
CRISPR/Cas

Zhejiang University
Jiaxing Academy of Agricultural Sciences
Wuxi Hupper Bioseed Ltd.
Hubei Collaborative Innovation Center for Grain Industry, China
Newcastle University, UK

Oomycete resistance: increased resistance against soybean root rot disease caused by Phytophthora sojae.
(Liu et al., 2023)

SDN1
CRISPR/Cas

Nanjing Agricultural University, China

Bacterial resistance: Strong resistance to Xanthomonas oryzae, causing bacterial blight, a devastating rice disease resulting in yield losses.
(Xie et al., 2017)

SDN1
TALENs

Chinese Academy of Sciences, China

Bacterial resistance: Strong resistance to Xanthomonas oryzae, causing bacterial blight, a devastating rice disease in Southeast Asia and West Africa. Bacteria enter the host and produce a toxin, which prevents the production of chlorophyl.
(Han et al., 2020)

SDN1
TALENs

Chinese Academy of Sciences
Hainan University, China

Broad-spectrum disease resistance without yield loss.
( Sha et al., 2023 )

SDN1
CRISPR/Cas

Huazhong Agricultural University
Chengdu Normal University
Jiangxi Academy of Agricultural Sciences
Anhui Agricultural University
BGI-Shenzhen
Northwest A&
F University
Shandong Academy of Agricultural Sciences, China
Université de Bordeaux, France
University of California
The Joint BioEnergy Institute, USA
University of Adelaide, Australia

Significant resistance to bacterial blight caused by Xanthomonas oryzae pv. oryzae (Xoo), sheath blight caused by Rhizoctonia solani and rice blast caused by Magnaporthe oryzae.
( Hu et al., 2021 )

SDN1
CRISPR/Cas

Huazhong Agricultural University
Jiangxi Agricultural University
Wuhan Towin Biotechnology Company Limited, China

Fungal resistance: Improved resistance to false smut, caused by Ustilaginoidea virens. False smut is one of the major fungal diseases of rice.
(Liang et al., 2018)

SDN2
CRISPR/Cas

Northwest A&
F University
Fujian Agriculture and Forestry University, China

Resistance to Phytophthora sojae, which severely impairs soybean production.
( Yu et al., 2022 )

SDN1
CRISPR/Cas

Northeast Agricultural University
Chinese Academy of Agricultural Sciences
Jilin Academy of Agricultural Science
Shanghai Jiao Tong University
Jiamusi Branch Academy of Heilongjiang Academy of Agricultural Sciences, China

Nematode resistance: Enhanced resistance to more virulent soybean cyst nematode (SCN). SCN is the most devastating post to soybean crop yields in the US.
(Wang et al., 2024)

SDN1
CRISPR/Cas

Henan Agricultural University
University of South Carolina, China

Viral resistance: Enhanced resistance to sweet potato virus disease (SPVD). SPVD is caused by the co-infection of sweet potato chlorotic stunt virus (SPCSV) and sweet potato feathery mottle virus.
(Yu et al., 2021)

SDN1
CRISPR/Cas

Jiangsu Normal University
Jiangsu Academy of Agricultural Sciences
Xuzhou Institute of Agricultural Sciences in Jiangsu Xuhuai District, China

Fungal resistance: stripe rust resistance, caused by Puccinia striiformis f. sp. tritici. In appropriate environmental conditions and susceptible varieties, stripe rust can cause huge grain yield and quality loss.
(Li et al., 2023)

SDN1
CRISPR/Cas

Fudan University
Chinese Academy of Sciences
University of the Chinese Academy of Sciences
China Agricultural University
Guangzhou University
School of Life Science
Shandong Academy of Agricultural Sciences
Ministry of Agriculture
National Engineering Research Center for Wheat and Maize
Sichuan Agricultural University
Nanjing Agricultural University, China
Université Paris Cité
Université Paris-Saclay, France

Bacterial resistance: enhanced resistance to Xanthomonas citri, causing citrus canker, one of the most serious diseases affecting the global citrus industry.
(Long et al., 2021)

SDN1
CRISPR/Cas

Southwest University/Chinese Academy of Agricultural Sciences, China

Fungal resistance: increased resistance to Botrytis cinerea.
(Wang et al., 2018)

SDN1
CRISPR/Cas

Northwest A&
F University and Ministry of Agriculture, China

Detection of Fumonisin B1 (FB1), a common mycotoxin found in agricultural products. FB1 is highly toxic, which can cause oxidative stress response and has been listed as a class 2B carcinogen. The method wx is highly specific and sensitive for FB1, has a rather simple, convenient and fast workflow.
( Qiao et al., 2023 )

SDN1
CRISPR/Cas

Kunming University of Science and Technology, China

Fungal resistance: contribute to Sclerotinia sclerotiorum resistance.
(Zhang et al., 2022)

SDN1
CRISPR/Cas

Huazhong Agricultural University, China

Bacterial resistance: Strong resistance to Xanthomonas oryzae, causing bacterial blight, a devastating rice disease resulting in yield losses.
(Zeng et al., 2020)

SDN1
CRISPR/Cas

Chinese Academy of Sciences, China

Fungal resistance: Improved resistance against Phytophtora without affecting potato growth and development.
(Bi et al., 2023)

SDN1
CRISPR/Cas

China Agricultural University
South China Agricultural University
Shanghai Normal University
Nanjing Agricultural University, China

Broad-spectrum bacterial blight resistance.
( Xu et al., 2019 )

SDN1
CRISPR/Cas

Shanghai Jiao Tong University, China

Visual detection of Alternaria solani, the causal agent of early blight in potato, which poses a persistant threat to potato production worldwide. The platform is specific, sensitive and suitable for high-throughput detection.
( Guo et al., 2023 )

SDN1
CRISPR/Cas

Jilin University
Jilin Agricultural University
Shenzhen Campus of Sun Yat-sen University, China

Bacterial resistance: Enhanced resistance to Xanthomonas oryzae pv. oryzae (Xoo) and X. oryzae pv. oryzicola (Xoc), which cause bacterial blight and bacterial leaf streak, respectively.
(Peng et al., 2022)

SDN1
CRISPR/Cas

Nanjing Agricultural University
Shandong Agricultural University
Jiangsu University of Science and Technology, China

Fungal resistance: Reduced susceptibility to Verticillium longisporum, fungal pathogen that causes stem striping in Brassica napus and leads to huge yield losses.
(Ye et al., 2024)

SDN1
CRISPR/Cas

Christian-Albrechts-University of Kiel
Institut für Zuckerrübenforschung
Hohenlieth-Hof, NPZ Innovation GmbH, Germany
Aswan University, Egypt
Fujian Agriculture and Forestry University, China

Bacterial resistance: Enhanced resistance to both blast and bacterial blight diseases, two major diseases having devastating impact on the yield of rice in most rice-growing countries.
(Zhou et al., 2021)

SDN1
CRISPR/Cas

South China Agricultural University
Huazhong Agricultural University
Yuan Longping High-Tech Agriculture Co. Ltd
Hunan Hybrid Rice Research Center
Yuan Longping High-Tech Agriculture Co. Ltd, China

Fungal resistance: Improved resistance to Magnaporthe oryzae.
(Lijuan et al., 2024)

SDN1
CRISPR/Cas

China National Rice Research Institute
Agricultural College of Yangzhou University, China

Fungal resistance: enhanced resistance to Magnaporthe oryzae, causing rice blast, one of the most destructive diseases affecting rice worldwide.
(Wang et al., 2016)

SDN1
CRISPR/Cas

Chinese Academy of Agriculture, China

Bacterial and fungal resistance: Resistance to bacterial blight and rice blight. Also spontaneous cell death, altered seed dormancy (pre-harvest sprouting) and enhanced growth.
(Liao et al., 2018)

SDN1
CRISPR/Cas

Sichuan Agricultural University, China

Fungal resistance: enhanced resistance against powdery mildew disease.
(Xu et al., 2023)

SDN1
CRISPR/Cas

Kyungpook National University
Rural Development Administration
Sunchon National University, South Korea
Lingnan Normal University, China

High level of powdery mildew resistance while maintaining normal crop
growth and yields.
( Li et al., 2022 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences, China

Fungal resistance: Enhanced resistance to blast without affecting the major agronomic traits. Rice blast caused by Magnaporthe oryzae, is a devastating disease affecting rice production globally
(Nawaz et al., 2020)

SDN1
CRISPR/Cas

Guangxi University
South China Agricultural University, China

Sensitive detection of two fungal pathogens (Diaporthe aspalathi and Diaporthe caulivora) that cause soybean stem canker. The method requires minimal equipment as well as training and shows potential for on-site screening.
( Sun et al., 2023 )

SDN1
CRISPR/Cas

Chinese Academy of Inspection and Quarantine
Shenyang Agricultural University
Huangpu Customs Technology Center
Technical Center of Hangzhou Customs
Dalian University, China

Resistance against leaf chewing insects: leaf-chewing insects cause yield loss and reduce seed quality in soybeans
(Zhang et al., 2022)

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Huazhong Agricultural University
Henan Agricultural University, China

Fungal resistance: enhanced resistance to powdery mildew (Erysiphe necator), a major fungal disease, threatening one of the most economically valuable horticular crops.
(Wan et al., 2020)

SDN1
CRISPR/Cas

Ministry of Agriculture, China
Northwest A&
F University
University of Maryland College Park, USA

Fungal resistance: Increased resistance to Phytophthora sojae, a pathogen severely impairing soybean production.
(Yu et al., 2021)

SDN1
CRISPR/Cas

Northeast Agricultural University
Chinese Academy of Agricultural Sciences
Shanghai Jiao Tong University
Jilin Academy of Agricultural Science
Jiamusi Branch Academy of Heilongjiang Academy of Agricultural Sciences
Heilongjiang Academy of Agricultural Sciences, China

Fungal resistance: higher resistance to Verticillium dahliae infestation. Cotton verticillium wilt/cotton cancer, is a destructive disease, leading to 250-310 million USD economic losses each year in China.
(Zhang et al., 2018)

SDN1
CRISPR/Cas

Chinese Academy of Sciences
Chinese Academy of Agricultural Sciences
Shanxi Academy of Agricultural Sciences, China

Bacterial resistance: Strong resistance to Xanthomonas oryzae, causing bacterial blight, a devastating rice disease resulting in yield losses.
(Xu et al., 2021)

SDN1
TALENs

Shanghai Jiao Tong University, China
Crop Diseases Research Institute, Pakistan

Oilseed rape mutant with non-abscising floral organs. Clerotinia stem rot (SSR), caused by Sclerotinia sclerotiorum is a detrimental fungal disease for oilseed rape. Petal infection is crucial to the prevalence of SSR in oilseed rape. Oilseed rape varieties with abscission-defective ﬂoral organs were predicted to be less susceptible to Sclerotinia infection and to have a longer ﬂowering period to enhance tourism income.
( Wu et al., 2022 )

SDN1
CRISPR/Cas

Yangzhou University, China

SDN1
CRISPR/Cas

Chinese Academy of Inspection and Quarantine
China Agricultural University, China

Fungal resistance: increased resistance against the fungus Puccinia striiformis f. sp. tritici (Pst). Wheat stripe rust is caused by Pst and is one of the most destructive wheat diseases, resulting in significant losses to wheat production worldwide.
(He et al., 2022)

SDN1
CRISPR/Cas

Northwest A&
F University
Hebei Agri cultural University, China

Bacterial resistance: Enhanced resistance to blast and bacterial blight.
(Zhang et al., 2024)

SDN1
CRISPR/Cas

China National Rice Research Institute, China

Disease resistant thermosensitive genic male sterility (TGMS) with enhanced resistance to rice blast and bacterial blight.
( Li et al., 2019 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China

Bacterial resistance: Strong resistance to Xanthomonas oryzae, causing bacterial blight, a devastating rice disease resulting in yield losses.
(Shan et al., 2013)

SDN1
TALENs

Chinese Academy of Sciences, University of Electronic Science and Technology of China, China
University of Minnesota, USA

Bacterial resistance: Strong resistance to Xanthomonas oryzae, causing bacterial blight, a devastating rice disease resulting in yield losses.
(Cai et al., 2017)

SDN1
TALENs

Shanghai Jiao Tong University
Yunnan Academy of Agricultural Sciences, China

Viral resistance: Resistance against potato leaf roll virus, potato virus Y, potato virus X and potato virus S, which have been recognized as the major potato viruses.
(Zhan et al., 2023)

SDN1
CRISPR/Cas

Hubei University
Huazhong Agricultural University
Chinese Academy of Agricultural Sciences, China

Increased resistance to drought stress by enhancing antioxidant capacity and defence system.
( Gao et al., 2022 )

SDN1
CRISPR/Cas

Henan Agricultural University
China Tobacco Sichuan Industrial Co., China

Enhanced resistance to Botrytis cinerea.
( Huang et al., 2022 )

SDN1
CRISPR/Cas

Beijing University of Agriculture
Capital Normal University, China

Rapid detection of toxigenic Fusarium verticillioides, a phytopathogenic fungus that causes Fusarium ear and stalk rot and poses a threat to maize yields. This accurate and portable detection equipment has great potential for detection of the pathogen, even in areas lacking proper lab equipment.
( Liang et al., 2023 )

SDN1
CRISPR/Cas

Institute of Food Science and Technology
North Minzu University
School of Food Science and Engineering, China
Gembloux Agro-Bio Tech, Belgium

Viral resistance: Resistance against Grapevine leafroll-associated virus 3 (GLRaV-3), which is one of the causal agents of grapevine leafroll disease (GLD). GLD severely impacts grapevine production.
(Jiao et al., 2022)

CRISPR/Cas

Northwest A&
F University, China

Fungal resistance to Oidium neolycopersici, causing powdery mildew, one of the most important diseases limiting the production of wheat.
( Zhang et al., 2017 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences, China

Traits related to improved food/feed quality

Fragrant sorghum. No fragrant sorghums are currently on the market. Extraordinary aromatic smell in both seeds and leaves. Experiments showed that fragrant sorghum leaves were attractable for animal feeding.
( Zhang et al., 2022 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences
Animal facility Institute of Genetics and Developmental Biology, China

Improved quality by reduced grain protein content (GPC). High GPC is negatively correlated between protein content and peak viscosity and breakdown value. High GPC is also positively correlated to protein content and hardness.
( Wang et al., 2020 )

SDN1
CRISPR/Cas

Jiangsu Key Laboratory of Crop Genetics and Physiology/Key Laboratory of Plant Functional Genomics of the Ministry of Education/Jiangsu Key Laboratory of Crop Genomics and Molecular Breeding
Jiangsu Co-Innovation Center for Modern Production Technology of Grain Crops
Agricultural College of Yangzhou University, China

Fragrant rice by introducing aroma into non-aromatic rice varieties. The genome edited fragrant rice was then used as starting material for molecular breeding to introduce both fragrance and high anthocyanin levels in rice.
( Shi et al., 2023 )

SDN1
CRISPR/Cas

Chinese Academy of Agriculture Sciences (CAAS)
Tianjin Academy of Agricultural Sciences
Chengdu National Agricultural Science and Technology Center, China

Reduction of steroidal glycoalkaloids (SGAs). SGAs in most potato tissues are toxic to humans when the fresh weight is over 200mg/kg. High SGAs content also damage the quality of potato tubers.
( Zheng et al., 2021 )

SDN1
CRISPR/Cas

Qinghai University, China

Reduction of amylose content (AC). AC is the predominant factor determining rice eating and cooking quality.
( He et al., 2020 )

SDN1
CRISPR/Cas

Northeast Agricultural University
Chinese Academy of Sciences
Jiangsu Academy of Agricultural Sciences
Northeast Agricultural University, China

Aromatic maize.
( Wang et al., 2021 )

SDN1
CRISPR/Cas

Shandong Normal University
Bellagen Biotechnology Co. Ltd
Chinese Academy of Sciences, China

High levels of monounsaturated fatty acids (MUFAs) in soybean seed oil. High MUFA content in vegetable oils can lead to significant health benefits and improve the oxidative stability, which are essential for both food usage and biodiesel (and other renewable resource) synthesis.
( Li et al., 2023 )

SDN1
CRISPR/Cas

Northeast Agricultural University, China

Reduced levels of polybrominated diphenyl ethers, organic pollutants which have great ecological and health risks, in the edible parts.
( Chen et al., 2023 )

SDN1
CRISPR/Cas

Zhejiang University
Zhejiang Provincial Key Laboratory of Organic Pollution Process and Control, China

Increased grain hardness and reduced grain width. Grain hardness index of hina mutants was 95.5 on average, while that of the wild type was only 53.7, indicating successful conversion of soft barley into hard barley.Grain hardness, defined as the resistance of the kernel to deformation, is the most important and defining quality of barley and wheat.
( Jiang et al., 2022 )

SDN1
CRISPR/Cas

Qinghai Normal University
Chinese Academy of Sciences, China

Improvement of starch quality.
( Wang et al., 2021 )

SDN1
CRISPR/Cas

Chinese Academy of Science

Shanghai Sanshu Biotechnology Co.
LTD, China
University of Kentucky, USA

High-amylose content (up to 56% in apparent amylose content) and resistant starch (up to 35%).
( Luo et al., 2021 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences
Shanghai Sanshu Biotechnology Co.,
Guangxi Subtropical Crops Research Institute, China

Lower levels of D hordein. D hordein is one of the storage proteins in the grain, with a negative effect on malting quality.
( Li et al., 2020 )

SDN1
CRISPR/Cas

Qinghai Province Key Laboratory of Crop Molecular Breeding
Chinese Academy of Sciences
University of Chinese Academy of Sciences, China

Lowering phytate synthesis in seeds. Phytate is an anti-nutritient.
( Vlčko and Ohnoutková, 2020 )

SDN1
CRISPR/Cas

Czech Academy of Sciences, Czech Republic

Increased contents of GABA, protein, crude fat, and various mineral contents. GABA-rich rice varieties can promote human nutrition, and ensure health.
( Chen et al., 2023 )

SDN1
CRISPR/Cas

Ministry of Agriculture and Rural Affairs, China

Reduced phytic acid (PA) synthesis in seeds, PA is an anti-nutritional compound.
( Liang et al., 2013 )

SDN1
TALENs

Chinese Academy of Sciences, China

Reduced arsenic content, a highly toxic metalloid harming human health. Inorganic Arsenic is listed as a carcinogen.
( Ye et al., 2017 )

SDN1
CRISPR/Cas

Huazhong Agricultural University, China

Sweeter kernels due to the accumulation of sugar rather than starch and waxy with an altered amylose/amylopectin ratio.
( Dong et al., 2019 )

SDN1
CRISPR/Cas

National Key Facility for Crop Gene Resources and Genetic Improvement
Anhui Agricultural University, China

Improved amylose levels to influence grain eating and cooking quality (ECQ).
( Huang et al., 2020 )

SDN1
CRISPR/Cas

Yangzhou University, China

Increased sucrose content.
( Ren et al., 2020 )

SDN1
CRISPR/Cas

Beijing Key Laboratory of Vegetable Germplasm Improvement
Capital Normal University
China Agricultural University, China
Cornell University
Robert W. Holley Center for Agriculture and Health, USA

Fine-tuning the amylose content, one of the major contributors to the eating and cooking quality.
( Zhang et al., 2022 )

SDN1
CRISPR/Cas

Shanghai Normal University, China

Modification of starch composition, structure and properties. Foods with a high amylose content (AC) and resistant starch (RS) offer potential to improve human health and lower the risk of serious non-infectious diseases.
( Li et al., 2020 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences (CAAS)
Nanjing Agricultural University, China

Fine-tuning sugar content. Consumer preference varies along regional, cultural, and age lines, thus the solution is to create a continuum of phenotypic “taste” changes
( Xing et al., 2020 )

Chinese Academy of Sciences
China Agricultural University, China

Increased tolerance to the heavy metal Cadmium.
( Liu et al., 2022 )

SDN1
CRISPR/Cas

Zhejiang University
Agricultural Ministry of China, China

Improved grain quality. The amylose content, gel consistency and pasting viscosity of grain starches are influencing the grain appearance, cooking/eating quality and starch physical characters.
( Zeng et al., 2020 )

SDN1
CRISPR/Cas

State Key Laboratory for Conservation and Utilization of Subtropical Agro‐Bioresources
Guangdong Laboratory for Lingnan Modern Agriculture
South China Agricultural University, China

Reduced amount of saturated fatty acids (FA) in soybean seeds for nutrititional improvement. FA are linked to cardiovascular diseases.
( Ma et al., 2021 )

SDN1
CRISPR/Cas

Zhejiang University, China
La Trobe University, Australia

Generation of a new glutinous Photothermosensitive Genic-Male-Sterile (PTGMS) line with a low amylose content. PTMGS line combines high-quality and high-light-efficiency use, disease and stress resistance.
( Teng et al., 2021 )

SDN1
CRISPR/Cas

Guangxi University
South China Agricultural University, China

Enhanced soluble sugar content in tomato fruit. Soluble sugar improves the sweetness and increases tomato sauce yield.
( Wang et al., 2021 )

SDN1
CRISPR/Cas

Xinjiang Academy of Agricultural Sciences
Xinjiang Agricultural University, China

Nattokinase (NK) producing cucumber. NK is effective in the prevention and treatment of cardiovascular disease.
( Ni et al., 2023 )

SDN2
CRISPR/Cas

Xuzhou University of Technology
Nankai University, China

Low tartaric acid.
( Ren et al., 2016 )

SDN1
CRISPR/Cas

University of Chinese Academy of Sciences
Chinese Academy of Sciences, China

Increased flavonoid content. Flavonoids play a role in fruit colour and are important for human health as favourable hydrophilic antioxidants.
( Zhou et al., 2023 )

SDN1
CRISPR/Cas

China Agricultural University
Chinese Academy of Sciences, China

High oleic acid, low linoleic content.
( al Amin et al., 2019 )

SDN1
CRISPR/Cas

Jilin Agricultural University, China

Biofortification: Enhanced Zinc and Manganese tolerance and increased Zinc and Manganese accumulation in rice grains.
(Qiao et al., 2019)

SDN1
CRISPR/Cas

Shenzhen University
University of Chinese Academy of Sciences, China

Low Cadmium (Cd) accumulating. Cadmium (Cd) is a non-essential heavy metal that is toxic to virtually all living organisms, including plants.
( Songmei et al., 2019 )

SDN1
CRISPR/Cas

Zhejiang University
Hubei Collaborative Innovation Center for Grain Industry
Zhejiang University
Jiaxing Academy of Agricultural Sciences, China

Altered gliadin levels resulting in improved end-use quality and reduced gluten epitopes associated with celiac disease. Gliadins are important for wheat end-use traits.
( Liu et al., 2023 )

SDN1
CRISPR/Cas

China Agricultural University, China
Research Centre for Cereal and Industrial Crops, Italy

Waxy phenotype, abolition of amylose.
( Qi et al., 2018 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China

Increased amylose content. Cereals high in amylose content (AC) and resistant starch (RS) offer potential health benefits and reduce risks of diseases such as coronary heart disease, diabetes and certain colon and rectum cancers.
( Sun et al., 2017 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China
University of California, USA
University of Liege, Belgium

Decreased cadmium accumulation in rice grain, while leaving important agronomic traits including yield, unaffected. Cadmium poses a health threat, as it is a highly toxic heavy metal for most living organisms
( Luo et al., 2023 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences
University of the Chinese Academy of Sciences
China National Rice Research Institute
Southern University of Science and Technology, China

Facilitated Isoproturon Metabolism and Detoxification: Improved growth, the Isoproturon (IPU)-induced cellular damage was attenuated, and IPU accumulation was significantly repressed
(Zhai et al., 2022)

SDN1
CRISPR/Cas

Nanjing Agricultural University, China

Lowered amylose content and viscosity, risen gel consistency and gelatinization temperature values, all resulting in improved eating and cooking quality.
( Song et al., 2023 )

SDN1
CRISPR/Cas

Jiangsu University
Institute of Food Crops
Yangzhou University, China

Fragrance by accumulation of the natural aroma substance 2-acetyl-1-pyrroline (2AP). Fragrance is one of the most important rice quality traits, with 2AP being the major contributor to aroma.
( Tang et al., 2021 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Hubei Academy of Agriculture Sciences
Guangdong Academy of Agricultural Sciences, China
Agricultural Research Center, Egypt

High fruit malate accumulation. Malate is a primary organic acid in tomato and a crucial compound that contributes to fruit flavor and palatability.
( Ye et al., 2017 )

SDN1
CRISPR/Cas

Huazhong Agricultural University, China
Cornell University, USA

Glossy green phenotype and reduced cuticular wax load.
( Liu et al., 2023 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Hunan Agricultural University
Tianjin Kernel Vegetable Research Institute, China

Improved fatty acid content: increased content of oleic acid, reduced erucic acid levels and slightly decreased polyunsaturated fatty acids content. Fatty acid composition is important for human health and shelf life.
(Shi et al., 2022)

SDN1
CRISPR/Cas

Zhejiang Academy of Agricultural Sciences, China

Increased protein content and increased grain weight. Increase in grain protein content has a positive effect on flour protein content and gluten strength, two quality parameters.
( Zhang et al., 2018 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences
University of Chinese Academy of Sciences
Shandong Normal University, China

Increased grain amylose content. Improving grain quality is one of the most important goals in rice breeding. Contribute to the breeding of rice cultivars with better eating and cooking quality, as cooking and eating quality is determined from amylose content.
( Liu et al., 2022 )

SDN1
CRISPR/Cas

Hunan Agricultural University
China National Seed Group Co., China

Increased grain weight and grain size. Carbohydrate and total protein levels also increased.
( Guo et al., 2021 )

SDN1
CRISPR/Cas

Sichuan Agricultural University, China
University of California, USA

Reduction of phytic acid (PA) in seeds. PA has adverse effects on essential mineral absorption and thus is considered as an anti-nutritive for monogastric animals.
( Khan et al., 2019 )

SDN1
CRISPR/Cas

Zhejiang University
Yangtze University, China

Reduced arsenic (As) accumulation in rice grain. Inorganic As is a carcinogen and decreasing the accumulation would improve the food safety of rice.
( Xu et al., 2024 )

SDN1
CRISPR/Cas

Nanjing Agricultural University, China

Low erucic acid (EA) content. Composition of fatty acids affects the edible and processing quality of vegetable oils. EA is potentially to cause health problems.
( Liu et al., 2022 )

SDN1
CRISPR/Cas

Huazhong Agricultural University, China

Decreased seed size and promoted seed germination. To improve consumer experience for flesh-consumed watermelons, no (or small and sparse) seeds are better because the flesh portion is larger.
( Wang et al., 2021 )

SDN1
CRISPR/Cas

Beijing Key Laboratory of Vegetable Germplasm Improvement, China

Reduced Cd accumulation.
( Chen et al., 2022 )

SDN1
CRISPR/Cas

South China Agricultural University
Guangdong Academy of Sciences, China

Increased soya bean isoflavone content and resistance to soya bean mosaic virus. Isoflavonoids play a critical role in plant-environment interactions and are beneficial to human health.
( Zhang et al., 2020 )

SDN1
CRISPR/Cas

Nanjing Agricultural University
Anhui Academy of Agricultural Science
Guangzhou University, China

Improved starch quality. Reduced amylopectin and increased amylose percentage.
( Wang et al., 2019 )

SDN1
CRISPR/Cas

Shanghai Institutes for Biological Sciences
Shanghai Sanshu Biotechnology Co. LTD
Chinese Academy of Science, China
University of Kentucky, USA

Increased phosphorus content and improved fruit quality.
( Zhang et al., 2023 )

SDN1
CRISPR/Cas

Shenyang Agricultural University
Ministry of Education, China

Increased flavonoid content, functioning as allelochemicals and insect deterrents.
( Lam et al., 2019 )

SDN1
CRISPR/Cas

The University of Hong Kong
The Chinese University of Hong Kong
Shenzhen
Zhejiang Academy of Agricultural Sciences
Nanjing Forestry University, China
Kyoto University, Japan

Waxy rice which lacks amylose. Waxy rice is regarded as a high-quality rice variant, also known as glutinous rice. Due to the unique properties of waxy rice starch, it is extensively used in the chemical industry, medicine, and daily human life.
( Fu et al., 2023 )

SDN1
CRISPR/Cas

Chengdu University of Traditional Chinese Medicine
Rice Research Institute of Sichuan Agricultural University
Meishan Dongpo District Agricultural and Rural Bureau, China

Increased vitamin C content, increased oxidation stress tolerance and increased ascorbate content.
( Zhang et al., 2018 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences, China

Improved cadmium tolerance by reducing the Cd transport from vacuole to cytosol in tobacco leaves.
( Jia et al., 2022 )

SDN1
CRISPR/Cas

Henan Agricultural University
Xiamen University, China

Fragrant rice.
( Shan et al., 2015 )

SDN1
TALENs

Chinese Academy of Sciences, China

High-quality sugar production by rice (98% sucrose content). Carbohydrates are an essential energy-source. Sugarcane and sugar beet were the only two crop plants used to produce sugar.
( Honma et al., 2020 )

SDN1
CRISPR/Cas

Fujian Agriculture and Forestry University, China
Faculty of Engineering
Kitami Institute of Technology
NagoyaUniversity
Tokyo Metropolitan University, Japan
Carnegie Institution for Science, USA

Yellow-seed production, a desirable trait with great potential for improving seed quality in Brassica crops. The formation of seed colour is due to the deposition of the oxidized form of a flavonoid, called proanthocyanidins (PA). Yellow seeds have a higher oil content.
( Zhai et al., 2019 )

SDN1
CRISPR/Cas

Huazhong Agricultural University, China

Promoted anthocyanin accumulation. Anthocyanins are plant secondary metabolites with a variety of biological functions.
( Tu et al., 2022 )

SDN1
CRISPR/Cas

Northwest A&
F University, China

Increased lycopene content. Lycopene plays a role in treating chronic diseases and lowering the risk of cardiovascular diseases and cancer. Enhanced contents of lycopene, phytoene, prolycopene, a-carotene, and lutein.
( Li et al., 2018 )

SDN1
CRISPR/Cas

China Agricultural University, China

Aromatic three-line hybrid.
( Hui et al., 2021 )

SDN1
CRISPR/Cas

China National Rice Research Institute, China

Altered lignin composition: decreased syringyl monolignol / guaiacylmonolignol (S/G) ratio. The monolignol ratio has been proposed to affect biomass recalcitrance and the resistance to plant disease.
(Cao et al., 2021)

SDN1
CRISPR/Cas

SouthwestUniversity, China
University of Wisconsin, USA

Low glutelin content in the rice germplasm: patients with chronic kidney disease (CKD) and phenylketonuria (PKU) need to eat rice with low glutelin content.
(Chen et al., 2022)

SDN1
CRISPR/Cas

Nanjing Branch of Chinese National Center for Rice Improvement
Yangzhou University
Henan Agricultural University
Jiangsu Academy of Agricultural Sciences, China
CSIRO Agriculture and Food, Australia

Improved fatty acid content: high oleic acid, decreased linoleic acid content. FA composition is important for human health and shelf life.
(Wen et al., 2018)

SDN1
TALENs

Guangdong Academy of Agricultural Sciences, China

Increased potassium concentrations (K+). Potassium is crucial for improving the quality of tobacco.
( Gao et al., 2024 )

SDN1
CRISPR/Cas

Yunnan Academy of Tobacco Agricultural Sciences/National Tobacco Genetic Engineering
Research Center
Chinese Academy of Agricultural Sciences, China

Fine-tuning the amylose content, one of the major contributors to the eating and cooking quality.
( Xu et al., 2021 )

Jiangsu Academy of Agricultural Sciences/Nanjing Branch of Chinese National Center for Rice Improvement
Yangzhou University
Chinese Academy of Sciences, China
CSIRO Agriculture and Food, Australia

Increasing seed oil content (SOC).
( Zhang et al., 2022 )

SDN1
CRISPR/Cas

Huazhong University of Science and Technology, China

Enhanced soybean aroma and functional marker for improving soybean flavor.
( Qian et al., 2022 )

SDN1
CRISPR/Cas

Zhejiang Academy of Agricultural Science
Ministry of Agriculture and Rural Affairs of China
Zhejiang University of Technology
Zhejiang Academy of Agricultural Sciences, China

Generation of seed lipoxygenase-free soybean. Lipoxygenases are responsible for an unpleasant beany flavor by the oxidation of unsaturated fatty acids, restricting human consumption.
( Wang et al., 2020 )

SDN1
CRISPR/Cas

Fujian Agriculture and Forestry University
Hebei Academy of Agricultural and Forestry Sciences, China

Increased carotene accumulation in rice endosperm.
( Shao et al., 2017 )

SDN1
CRISPR/Cas

Key Laboratory of Rice Biology and Genetic Breeding, China

Enhanced levels of glucoraphanin. The hydrolysis product of glucoraphanin has powerful anticancer activity.
( Zheng et al., 2023 )

SDN1
CRISPR/Cas

Sichuan Agricultural University
Zhejiang University
Bijie Institute of Agricultural Science, China

Reduced phytic acid (PA) synthesis in seeds, PA is an anti-nutritional compound.
( Liang et al., 2013 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences, China

Zero amylose grain. Amylose levels significantly influence processing of grain.
( Li et al., 2024 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences
Qinghai University
Qinghai Academy of Agricultural and Forestry
Sciences
Shandong Academy of Agricultural Sciences, China

Fragrant glutinous hybrid rice.
( Tian et al., 2023 )

SDN1
CRISPR/Cas

Huazhong Agricultural University, China

Highly specific detection of Ochratoxin A (OTA) in cereal samples. OTA is classified as a Class 2B carcinogens. The method can be flexibly customized to detect a wide range of small molecular targets and holds great promise as a versatile sensing kit with applications in various fields requiring sensitive and specific detection of diverse analytes.
( Chen et al., 2023 )

SDN1
CRISPR/Cas

Ningbo University
Hainan University
Ningbo Clinical Pathology Diagnosis Center, China
University of New South Wales, Australia

High-oleic acid content. Oleic acid has better oxidative stability than linoleic acid due to its monounsaturated nature. High levels of linoleic acid reduces the oxidative stability of cottonseed oil, which can cause rancidity, a short shelf life and production of detrimental trans-fatty acids.
( Chen et al., 2020 )

SDN1
CRISPR/Cas

Cotton Research Center of Shandong Academy of Agricultural Sciences
Huazhong Agricultural University, China

Boosted cytokinin biosynthesis and elevated cucumber fruit wart formation. Warty fruit is an important quality trait that greatly affects market value and fruit appearance.
( Wang et al., 2022 )

SDN1
CRISPR/Cas

China Agricultural University, China

Improve glutinosity in elite varieties. Decreased amylose content without affecting other desirable agronomic traits.
( Zhang et al., 2018 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences, China
Purdue University
University of Queensland, USA

Rice grain with a reduced amino acid and total protein content without affecting the agronomic traits of the plant. Additionally, the grain showed improved cooking and eating quality.
( Yang et al., 2023 )

SDN1
CRISPR/Cas

Yangzhou University, China

Reduction in cadmium accumulation. Cadmium is a heavy metal, harmful for human health. Cadmium accumulation represents a severe threat to people consuming rice as a staple food.
( Yang et al., 2019 )

SDN1
CRISPR/Cas

Nanjing Agricultural University
Chinese Academy of Sciences, China

Modified fatty acid profile: increased oleic acid, decreased linoleic and linolenic acid content.
(Huang et al., 2020)

SDN1
CRISPR/Cas

National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, China

Increased phosphorus and anthocyanin content.
( Zhang et al., 2023 )

SDN1
CRISPR/Cas

Shenyang Agricultural University
Ministry of Education, China

Improved fatty acid content: high oleic acid, decreased linoleic acid content to improve nutritional characteristics, increase shelf-life and frying stability.
(Zhang et al., 2023)

SDN1
CRISPR/Cas

Jilin Agricultural University, China

Low amylose content to improve the rice eating quality.
( Mao et al., 2022 )

Guangdong Academy of Agricultural Sciences
Guangdong Key Laboratory of New Technology in Rice Breeding
Guangdong Rice Engineering Laboratory, China

Increased gamma-Aminobutyric acid (GABA) content. GABA is a nonproteogenic amino acid with health-promoting functions.
( Lee et al., 2018 )

SDN1
CRISPR/Cas

China Agricultural University, China

Regulate cucumber fruit wart formation. Warty fruit in cucumber is an important quality trait that greatly affects fruit appearance.
( Wang et al., 2021 )

SDN1
CRISPR/Cas

China Agricultural University, China

Reduced content of saturated fatty acids: low palmitic and high oleic acid. Great potential for improving peanut oil quality for human health.
(Tang et al., 2022)

SDN1
CRISPR/Cas

Qingdao Agricultural University, China

Enriched levels of Gamma-amino butyric acid (GABA). GABA lowers blood pressure, has anti-aging effects, and activates the liver and kidney.
( Chen et al., 2022 )

SDN1
CRISPR/Cas

Guangdong Academy of Agricultural Sciences, China

Conversion of a normal maize hybrid into a waxy version, a specialty that produces mainly amylopectin starch with special food or industrial values and thus has high economic value.
( Qi et al., 2020 )

SDN1
CRISPR/Cas

Anhui Agricultural University
Chinese Academy of Agricultural Sciences/National Key Facility for Crop Gene Resources and Genetic Improvement, China

Reduced cadmium content. Cadmium poses a health treath, as it is a highly toxic heavy metal for most living organisms.
( Tang et al., 2017 )

SDN1
CRISPR/Cas

Hunan Agricultural University, Hunan Hybrid Rice Research Center, Normal University, China

Imrpoved rice eating and cooking quality with down-regulated rice grain protein content, which is negatively regulated to ECQ.
( Yang et al., 2022 )

SDN1
CRISPR/Cas

Yangzhou University, China

Increased gamma-Aminobutyric acid (GABA): 1.34-fold to 3.50-fold increase in GABA accumulation. GABA is a nonprotegeonomic amino acid with health-promoting functions.
(Li et al., 2017)

SDN1
CRISPR/Cas

China Agricultural University, China

Improved seed oil content: increased levels of monounsaturated fatty acids and decreased levels of polyunsaturated fatty acids.
(Wang et al., 2022)

SDN1
CRISPR/Cas

Huazhong Agricultural University, China
National Research Council Canada, Canada

Promoted phenolic acid biosynthesis. Salvia is tradional Chinese medicine with great medical value to treat cardio- and cerebrovascular diseases. Phenolic acids make up a big part of the bioactive compounds.
( Shi et al., 2021 )

SDN1
CRISPR/Cas

East China University of Science and Technology
Zhejiang Chinese Medical University, China
University of Hawaii at Manoa, USA

Increased lysophospholipid content and enhanced cooking and eating quality. Lysophospholipid (LPL) is derived from the hydrolysis of phospholipids and plays an important role in rice grain quality.
( Khan et al., 2020 )

SDN1
CRISPR/Cas

Zhejiang University, China

Reducing polyunsaturated fatty acids content and increased content of monounsaturated fatty acids. High levels of polyunsaturated fatty acids in natural soybean oil renders the oil susceptible to the development of unpalatable flavors and trans fatty acids.
( Fu et al., 2022 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China

Reduced flavonoids and improved fatty acid composition with higher linoleic acid and linolenic acid, valuable for rapeseed germplasm and breeding. The genetic improvement has great significance in the economic value of rapeseeds.
( Xie et al., 2020 )

SDN1
CRISPR/Cas

Yangzhou University
The Ministry of Education of China, China
University of Western Australia, Australia

Changing grain composition: decrease in the prolamines, an increase in the glutenins, increased starch content, amylose content, and β-glucan content. The protein matrix surrounding the starch granules was increased.
(Yang et al., 2020)

SDN1
CRISPR/Cas

Sichuan Agricultural University, China
Norwich Research Park, UK
CSIRO Agriculture and Food, Australia

Traits related to increased plant yield and growth

Improved rice grain shape and appearance quality. Potential application in breeding of rice varieties with optimized grain morphologies. Slender grain shape.
( Zhao et al., 2018 )

SDN1
CRISPR/Cas

Yangzhou University, China

Increased seed weight.
( Shen et al., 2017 )

SDN1
CRISPR/Cas

Yangzhou University, China

Improve plant architecture to increase yield. Plant height and branch number are directly correlated with yield.
( Zheng et al., 2020 )

SDN1
CRISPR/Cas

Ministry of Agriculture, China
Wilkes University, USA

Higher yield than wild-type (WT) plants due to increased grain number per panicle, elevated grain weight, and enhanced harvest index.
( Wei et al., 2022 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Shanghai Normal University, China

Improved grain yield by promoting outgrowth buds and increasing tiller number.
( Lu et al., 2018 )

SDN1
CRISPR/Cas

Wuhan Institute of Bioengineering
Huazhong Agricultural University, China

Generation of important yield-related trait characteristics: dense and erect panicles and reduced plant height.
(Wang et al., 2017)

SDN1
CRISPR/Cas

Syngenta Biotechnology, China

Improved yield and fragrance.
( Usman et al., 2020 )

SDN1
CRISPR/Cas

Guangxi University
South China Agricultural University, China

Improved pod shattering resistance. Pod shattering has been a negatively selected trait in soybean domestication and breeding as it can lead to devastating yield loss of soybean.
( Zhang et al., 2022 )

SDN1
CRISPR/Cas

Fujian Agriculture and Forestry University
Heilongjiang Bayi Agricultural University
Hebei Academy of Agricultural and Forestry Sciences, China

Regulated inflorescence and flower development. More flowers and more fruit produced upon vibration-assisted fertilization.
( Hu et al., 2022 )

SDN1
CRISPR/Cas

Université de Toulouse, France
Chongqing University, China

Increased density by early-flowering phenotype under long-day conditions.
( Li et al., 2020 )

SDN1
CRISPR/Cas

Shandong Agricultural University
South China Agricultural University
Chinese Academy of Agricultural Sciences
Guangdong Laboratory for Lingnan Modern Agriculture, China

Early heading. Heading date is an important agronomic trait that affects climatic adaptation and yield potential.
( Fan et al., 2023 )

SDN1
CRISPR/Cas

Henan Agricultural University, China

Improved nitrogen use efficiency.
( Li et al., 2018 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Huazhong Agricultural University, China
University of California, USA

OsGEF5 and OsGDI1 single mutants show significantly reduced height and longer and thinner grains.
( Shad et al., 2022 )

SDN1
CRISPR/Cas

Huazhong Agricultural University
Hubei Hongshan Laboratory, China

Improved grain quality without severe yield penalty under nitrogen reduction conditions.
( He et al., 2022 )

SDN1
CRISPR/Cas

Rice Research Institute of Shenyang Agricultural University
Tianjin Tianlong Science and Technology Co. LTD.
National Japanica Rice Research and Development Center, China

Improvement for larger kernel and yield.
( Ma et al., 2015 )

SDN1
CRISPR/Cas

Northwest A &
F University
Chinese Academy of Agricultural Sciences, China

Enlarged grain phenotype.
( Wang et al., 2023 )

SDN1
CRISPR/Cas

Hebi Academy of Agricultural Sciences
Henan Agricultural University, China

Generating male sterility lines (MLS). Using MLS in hybrid seed production for monoclinous crops reduces costs and ensures high purity of the varieties because it does not produce pollen and has exserted stigmas.
( Li et al., 2016 )

SDN1
CRISPR/Cas

Shanghai Jiao Tong University, China

Longer root hairs. Root hairs effectively enlarge the soil-root contact area and play essential roles for nutrient and water absorption.
( Yang et al., 2023 )

SDN1
CRISPR/Cas

Zhejiang University
Linyi University
Hunan Agricultural University, China

Improvement of yield by reducing the "easy to shatter" trait. Reduced seed shattering ensures better stability during the harvesting processes and improved yields.
( Sheng et al., 2020 )

SDN1
CRISPR/Cas

Hunan Agricultural University
Hunan Hybrid Rice Research Center
Hunan Academy of Agricultural Sciences, China

Increased seed oil content (SOC). SOC is a major determinant of yield and quality.
( Karunarathna et al., 2020 )

SDN1
CRISPR/Cas

Christian-Albrechts-University of Kiel, Germany
Zhejiang University, China

Bigger grains, increased grain weight.
( Zhang et al., 2018 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences, China

Dwarf phenotype, which can aid in obtaining more compact, densely planted soybean varieties to boost productivity.
( Xiang et al., 2024 )

SDN1
CRISPR/Cas

Wuhan Polytechnic University
Chinese Academy of Agricultural Sciences, China

Super-dwarf phenotype. Rice plants with compact growth habits and reduced plant height can be useful in some environments.
( Peng et al., 2023 )

SDN1
CRISPR/Cas

Hunan Agricultural University
Chinese Academy of Agricultural Sciences
Agricultural College of Yangzhou University
Tianjin Academy of Agriculture Sciences, China

Increasing the number of seeds per pod (NSPP), an important yield determinant.
( Cai et al., 2021 )

SDN1
CRISPR/Cas

South China Agricultural University, China

Elongated, occasionally peanut-like shaped fruit.
( Zheng et al., 2022 )

SDN1
CRISPR/Cas

Nagoya University
Kanazawa University, Japan
Huazhong Agricultural University, China

More and longer lateral roots, more xylem and increased development of secondary vascular tissues: plants more suitable for biofuel and bioenergy production.
(An et al., 2023)

SDN1
CRISPR/Cas

Zhejiang A &
F University, China

Semi-dwarf phenotype with desired agronomic traits: tolerance to low phosporus levels and broad-spectrum resistance to diseases and insects.
(Hu et al., 2019)

SDN1
CRISPR/Cas

China National Rice Research Institute, China

Early-flowering varieties. The timing of flowering is an important event in the life cycle of flowering plants.
( Jiang et al., 2018 )

SDN1
CRISPR/Cas

Hunan Agricultural University, China
Université de Strasbourg, France

Decreased spike rachis node number and increased grain size and weight.
( Fan et al., 2023 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Hainan Yazhou Bay Seed Laboratory
Shandong Academy of Agricultural Sciences
China Agricultural University
Hubei Academy of Agricultural Sciences, China

Increased seed weight.
( Hu et al., 2018 )

SDN1
CRISPR/Cas

Fudan University, China

Altered plant architecture to increase yield: more compact plant architecture.
(Kong et al., 2023)

SDN1
CRISPR/Cas

Nanjing Agricultural University
Chinese Academy of Agricultural Sciences
Hebei Academy of Agricultural and Forestry Sciences, China

Increased seeds number per husk, higher seed weight.
( Yang et al., 2018 )

SDN1
CRISPR/Cas

Huazhong Agricultural University, China

Improved rice yield and immunity.
( Li et al., 2022 )

SDN1
CRISPR/Cas

Huazhong Agricultural University
Chinese Academy of Agricultural Sciences, China

Dwarf stature and a lesion-mimic phenotype. Fungal resistance: enhanced resistance to the pathogen Magnaporthe oryzae. Increased content of salicylic acid and induced plant defense responses.
(Ma et al., 2018)

SDN1
CRISPR/Cas

Peking University
Chinese Academy of Agricultural Sciences, China

Grain yield, regulation of seed development.
( Yuan et al., 2017 )

SDN1
CRISPR/Cas

Nanjing Agricultural University, China

Improved grain yield by modulating pyruvate enzymes and cell cycle proteins, leading to increased grain size. The grain size is a major determinant for rice yield and a vital trait for domestication and breeding.
( Usman et al., 2020 )

SDN1
CRISPR/Cas

Guangxi University
South China Agricultural University, China

Increased pollen activity, subsequently inducing fruit setting.
( Wu et al., 2022 )

SDN1
CRISPR/Cas

South China Agricultural University
Chongqing University, China
Université de Toulouse, France

Enhanced rice grain yield by decoupling panicle number and size
( Song et al., 2022 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences
Shandong Agricultural University
Hainan Yazhou Bay Seed Laboratory, China

Increased bending strength. Stalk lodging, which is generally determined by stalk strength, results in considerable yield loss and has become a primary threat to maize yield under high-density planting.
( Zhang et al., 2020 )

SDN1
CRISPR/Cas

China Agricultural University, China
Iowa State University, USA

Improved plant architecture: increased shoot branching, reduced plant height, increased number of leaves and nodes and reduced total plant biomass.
(Gao et al., 2018)

SDN1
CRISPR/Cas

Southwest University
Yunnan Academy of Tobacco Agricultural Sciences, China

Semi-dwarf phenotype to improve lodging resistance and increased seed dormancy. Increased seed dormancy can be beneficial for use in the malting industry.
( Cheng et al., 2023 )

SDN1
CRISPR/Cas

University of Tasmania
Murdoch University
Department of Primary Industries and Regional Development, Australia
Chinese Academy of Agricultural Sciences, China

Increased grain weight and grain size. Carbohydrate and total protein levels also increased.
( Guo et al., 2021 )

SDN1
CRISPR/Cas

Sichuan Agricultural University, China
University of California, USA

Increased yield.
( Huang et al., 2018 )

SDN1
CRISPR/Cas

Yunnan University
Chinese Academy of Sciences
BGI-Baoshan, China

Promote outgrowth buds and increase tiller number.
( Lu et al., 2017 )

SDN1
CRISPR/Cas

Wuhan Institute of Bioengineering
Huazhong Agricultural University
Chinese Academy of Sciences, China

Only female flowers. Allows earlier production of hybrids, higher yield, and more concentrated fruit set.
( Hu et al., 2017 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences,
China

Significantly improved photosynthesis and decreased leaf angles. The plant architecture is ideal for dense planting.
( An et al., 2022 )

SDN1
CRISPR/Cas

Huazhong Agricultural University, China

Increased tassel branch number (TBN), one of the important agronomic traits that contribute to the efficiency of seed production.
( Guan et al., 2022 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China

Longer grains and increased glume cell length.
( Sheng et al., 2022 )

SDN1
CRISPR/Cas

China Agricultural University
Chinese Academy of Sciences, China

Bigger seeds and increased yield.
( Xie et al., 2024 )

SDN1
CRISPR/Cas

Anhui Agricultural University
Anhui Agricultural University
Bellagen Biotechnology Co. Ltd
Ministry of Agriculture and Rural Affairs
Southern University of Science and Technology
Hainan Yazhou Bay Seed Laboratory, China

Increased breaking force, leading to improved lodging resistance.
( Dang et al., 2023 )

SDN1
CRISPR/Cas

Shenyang Agricultural University/Key Laboratory of Northern geng Super Rice Breeding, China

Regulate shade avoidance. Soybean displays the classic shade avoidance syndrome (SAS), which leads to yield reduction and lodging under density farming conditions.
( Lyu et al., 2020 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Jilin Agricultural University
Shandong Agricultural University
Northeast Agricultural University, China

Increased grain size and chalkiness.
( Li et al., 2022 )

SDN1
CRISPR/Cas

Henan Agricultural University, China

Delayed heading date with improved yield-related traits e.g. height, tiller number and grain weight.
( Li et al., 2023 )

SDN1
CRISPR/Cas

South China Agricultural University
Guangdong Laboratory for Lingnan
Modern Agriculture, China

Semi-dwarf phenotype. Plant height is an important agronomic trait of rice, it directly affects the yield potential and lodging resistance.
( Han et al., 2019 )

SDN1
CRISPR/Cas

Guangxi University
South China Agricultural University
Guangxi University, China

Increased nodule numbers. Soybean is a globally important crop for oil production and protein for human diet.
( Bai et al., 2019 )

SDN1
CRISPR/Cas

Fujian Agriculture and Forestry University
Nanchang University, China

Enlarged leaf and petal sizes resulting in bigger flowers. The size of a floral organ is one of the ornamental traits of strawberry.
( Zhao et al., 2023 )

SDN1
CRISPR/Cas

Shandong Agricultural University, China

Altered grain number per panicle.
( Shen et al., 2016 )

SDN1
CRISPR/Cas

National Rice Research Institute, China

Shortened flowering time and maturity, determining their favourable latitudinal zone for cultivation.
( Gao et al., 2024 )

SDN1
CRISPR/Cas

Syngenta Seed Technology China Co., China

Semi-dwarf phenotype. High varieties are challenged by weak lodging and damages caused by storms, dwarf varieties are suitable for mechanized plant maintenance and fruit harvesting.
( Shao et al., 2020 )

SDN1
CRISPR/Cas

Guangdong Academy of Agricultural Sciences
Hunan Agricultural University
Chinese Academy of Sciences
University of Chinese Academy of Sciences, China
University of Florida, USA

Regulated sepal growth
( Xing et al., 2022 )

SDN1
CRISPR/Cas

China Agricultural University
Chinese Academy of Sciences
Zhejiang University, China
University of Nottingham, UK

Increased spikelet number and delayed heading date. Two traits that are crucial and correlated to yield in wheat.
( Chen et al., 2022 )

SDN1
CRISPR/Cas

China Agricultural University, China

Increased grain number per main panicle and an increased seed settling rate.
( Qian et al., 2017 )

SDN1
CRISPR/Cas

China Agricultural University, China

Increased nitrogen utilization efficiency under high nitrate concentrations.
( Hang et al., 2023 )

SDN1
CRISPR/Cas

Guizhou University
Guangdong Provincial Key Laboratory of Applied Botany
Guangdong Academy of Agricultural Sciences, China

Increased yield potential by nitrogen use efficiency. Nitrogen fertilizer has been applied broadly to increase yield. However, low nitrogen use efficiency causes environmental pollution and ecological deterioration by the nitrogen fertilizers.
( Zhang et al., 2021 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Zhengzhou University, China

Larger fruits with more locules and larger shoot apical meristem.
( Song et al., 2022 )

SDN1
CRISPR/Cas

South China Agricultural University, China
University of Toulouse, France

Shorter flowering time and increased yield.
( Cheng et al., 2023 )

SDN1
CRISPR/Cas

Jilin Normal University
Jilin Academy of Agricultural Sciences, China

Increased spine density. The “numerous spines (ns)” cucumber varieties are popular in Europe and West Asia.
( Liu et al., 2022 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China

Increased seed number per silique, which increases the mustard yield per plant.
( Wang et al., 2021 )

SDN1
CRISPR/Cas

Huazhong Agricultural University, China

Dwarf phenotype. Tomatoes with compact growth habits and reduced plant height can be useful in some environments.
( Ao et al., 2023 )

SDN1
CRISPR/Cas

Chongqing University, China

Improve biomass yield and salinity tolerance.
( Guan et al., 2020 )

SDN1
CRISPR/Cas

China Agricultural University
Shandong institute of agricultural sustainable development
Beijing Sure Academy of Biosciences, China
Oklahoma State University, USA

Delayed heading date, increased yield and reduced chalkiness under field high temperature stress.
( Li et al., 2022 )

SDN1
CRISPR/Cas

Huazhong Agricultural University
Hubei Academy of Agricultural Sciences

Hubei Hongshan Laboratory, China

Improved grain length and weight by promoting cell proliferation in spikelet hull
( Wu et al., 2022 )

SDN1
CRISPR/Cas

Chongqing University, China

Promoted rice growth and productivity.
( Miao et al., 2018 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences, China
Purdue University, USA

Genetic diversity.
( Shen et al., 2017 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China
Yangzhou University, China

Accelerated seedling growth. Because seedling growth and development are the basis of rice tillering and reproduction, rapid seedling growth and fast sprouting from the soil are vital for the emergence rate and yield.
( Teng et al., 2023 )

SDN1
CRISPR/Cas

Hangzhou Normal University
Inner Mongolia University
Zhejiang Academy of Agricultural Sciences
Chinese Academy of Agricultural Sciences, China

Delayed flowering, which can increase grain yield and quality.
( Zhou et al., 2024 )

SDN1
CRISPR/Cas

Northeast Forestry University
Chinese Academy of Sciences
Graduate University of Chinese Academy of Sciences
Beidahuang Group Erdaohe Farm CO., China

Improved root growth under high and low nitrogen conditions.
( Wang et al., 2017 )

SDN1
CRISPR/Cas

Anhui Agricultural University
Chinese Academy of Agricultural Sciences, China

Promoting nodulation: up-regulation of expression levels of genes involved in nodulation. Nitrogen-fixing symbiotic nodules strongly up regulate yield.
(Wang et al., 2022)

SDN1
CRISPR/Cas

Beijing Institute of Technology
Chinese Academy of Agricultural Sciences, China

Dwarf phenotype to improve crop yield: lodging-resistant, compact, and perform well under high-density planting.
(Sun et al., 2020)

SDN1
CRISPR/Cas

Shenyang Agricultural University
National &
Local Joint Engineering Research Center of Northern Horticultural Facilities Design &
Application Technology
College of Bioscience and Biotechnology, China

Altered spike architecture and grain treshability to increase grain production.
( Liu et al., 2020 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China

Altered plant architecture along with a shorter plant height, grain size and increased spikelets and grain density.
( Zhang et al., 2023 )

SDN1
CRISPR/Cas

Shanghai Agrobiological Gene Center, China

Improved high-density yield and drought/osmotic stress tolerance.
( Chen et al., 2020 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Shanxi Academy of Agricultural Sciences, China
Texas Tech University, USA

Reduced seed shattering. Seed shattering is one of the main constraints on grain production in African cultivated rice, which causes severe grain losses during harvest.
( Ning et al., 2023 )

SDN1
CRISPR/Cas

China Agricultural University, China
Africa Rice Center, Benin

Early heading phenotype that escapes from cold stress and achieves high yield potential.
( Zhou et al., 2023 )

SDN1
CRISPR/Cas

Nanjing Agricultural University
Institute of Lianyungang Agricultural Science of Xuhuai Area/Lianyungang Institute of Agricultural Sciences
Chinese Academy of Agricultural Sciences, China

Helical and vine-like growth. Helical growth is an economical way for plant to obtain resources.
( Yang et al., 2020 )

SDN1
CRISPR/Cas

Huazhong Agricultural University, China

Altered plant architecture to inrease yield: increased node number on the main stem and branch number.
(Bao et al., 2019)

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Huazhong Agricultural University, China
Duy Tan University, Vietnam
RIKEN Center for Sustainable Resource Science, Japan

Enhanced grain yield and semi-dwarf phenotype by manipulating brassinosteroid signal pathway.
( Song et al., 2023 )

SDN1
CRISPR/Cas

China Agricultural University, China
Hard Winter Wheat Genetics Research Unit, USA

Altered grain number per panicle and increased seed weight.
( Li et al., 2016 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences, China

Control flowering time, an important determinant for soybean yield and adaptation.
( Wang et al., 2023 )

SDN1
CRISPR/Cas

Guangzhou University
Yunnan Agricultural University
Nanjing Agricultural University
Key Laboratory of Crop Genetics and Breeding of Hebei, China

Enhanced photosynthesis and decreased leaf angles for improved plant architecture and high yields.
( An et al., 2022 )

SDN1
CRISPR/Cas

Huazhong Agricultural University, China

Dwarf and high tillering phenotypes.
( Yang et al., 2017 )

SDN1
CRISPR/Cas

Shenzhen University
The Chinese University of Hong Kong, China

Regulation of pollen tube growth. The tube grows in female reproductive tissues to transport two sperm cells into the embryo sac for double fertilization during sexual reproduction.
( Liu et al., 2017 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences
University of Chinese Academy of Sciences, China

Improved yield under short day conditions.
( Wang et al., 2023 )

SDN1
CRISPR/Cas

South China Agricultural University, China

Semi-dwarf phenotype to improve product and lodging resistance.
( Zhang et al., 2020 )

SDN1
CRISPR/Cas

Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, China

More flowers in both determinate and indeterminate cultivars and more produced fruit.
( Hu et al., 2022 )

SDN1
CRISPR/Cas

Université de Toulouse
Université Bordeaux, France
Chongqing University, China

Plants with longer primary roots and more crown roots, as well as increased sensitivity to auxins and cytokinins. The rice root system is important for growth.
( Mao et al., 2019 )

SDN1
CRISPR/Cas

Fudan University
Sichuan Agricultural University
Shanghai Normal University
Chinese Academy of Sciences, China

Reduction of plant height through accumulation of ceramides. Plant height is an important agronomic trait of rice, it directly affects the yield potential and lodging resistance.
( Wang et al., 2023 )

SDN1
CRISPR/Cas

Nanchang University
Henan Agricultural University, China
Hokkaido University, Japan

Late flowering. Photoperiod sensitivity limits geographical range of cultivation.
( Cai et al., 2017 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China

Increased grain number due to increased meristem activity and enhanced panicle branching.
( Li et al., 2013 )

SDN1
ZFN

Chinese Academy of Sciences
National Hybrid Rice Research and Development Center
Chinese Academy of Agricultural Sciences
China National Hybrid Rice Research and Development Center
Wuhan University, China

Compact architecture with a smaller petiole angle than wild-type plants.
( Zhang et al., 2022 )

SDN1
CRISPR/Cas

Fujian Agriculture and Forestry University
Beijing Vocational College of Agriculture
Xiamen University, China

Overexpression causes strongly promoted stem elongation, lower expression resulted in dwarf phenotype.
( Mu et al., 2022 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China

Increased yield.
( Zhou et al., 2019 )

SDN1
CRISPR/Cas

University of Electronic Science and Technology of China
Xichang University, China
University of Maryland, USA

Dwarf phenotype to increase yield.
( Zhou et al., 2023 )

SDN1
CRISPR/Cas

Nanchang University
Jiangxi Academy of Agricultural Sciences, China

Increased seed weight.
( Ji et al., 2017 )

SDN1
CRISPR/Cas

Agronomy College of Henan Agricultural University, China

Increased formation of adventitious roots (ARs). The formation of ARs is extremely important to the large-scale vegetative propagation of elite genotypes in many economically important woody species.
( Ran et al., 2023 )

SDN1
CRISPR/Cas

Nanjing Forestry University
Yangzhou University, China

Increased plant height, longer roots, smaller root growth angle and increased tuber weight.
( Zhao et al., 2024 )

SDN1
CRISPR/Cas

Yunnan Agricultural University
Chinese Academy of Sciences
Xuanhan County Plant Quarantine Station
Yuguopu District Agricultural Comprehensive Service Center
Ning'
er County Plant Protection and Plant Quarantine Station, China

Semi-dwarf phenotype and compact architecture to increase yield. Plant height and branch angle are the major architectural factors determining yield.
( Fan et al., 2021 )

SDN1
CRISPR/Cas

Ministry of Agriculture and Rural Affairs, China
Wilkes University, USA

Improved grain length and weight by promoting cell proliferation.
( Wu et al., 2022 )

SDN1
CRISPR/Cas

Chongqing University, China

Increased yield potential trough improved nitrogen use efficiency. Enhanced tolerance to N starvation, and showed delayed senescence and increased grain yield in field conditions. Lowered use of N fertilizer.
( Zhang et al., 2021 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Zhengzhou University, China

Promote growth of axillary buds. Lateral branches develop from the axillary buds. The number of side branches is very important to plant architecture, which influences the yield and quality of the plant.
( Li et al., 2021 )

SDN1
CRISPR/Cas

Guizhou University
Northwest A&
F University
Shandong Agricultural University
Northeast Agricultural University
Shanxi University, China
Oxford University
University of Bedfordshire, UK

Early flowering and maturity. Flowering time (heading date) is an important trait for crop yield and cultivation.
( Wang et al., 2020 )

SDN1
CRISPR/Cas

Sinobioway Bio-Agriculture Group, Co., China
Corteva™ Agriscience, USA

Reduction of soybean plant height and shortening of the internodes. The height of the soybean plant is a key trait that significantly impacts the yield.
( Cheng et al., 2019 )

SDN1
CRISPR/Cas

Guangzhou University
Chinese Academy of Sciences
University of Chinese Academy of Sciences, China

Enhanced photosynthesis and increases seed yield.
( Hu et al., 2022 )

SDN1
CRISPR/Cas

Nanjing Agricultural University
Chinese Academy of Sciences
Henan Institute of Science and Technology, China

Semi-dwarf phenotype with increased lodging resistance.
( Zhang et al., 2020 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China

Increased yield: plants produced more tillers and grains than azygous wild-type controls and the total yield was increased up to 15 per cent.
(Holubova et al., 2018)

SDN1
CRISPR/Cas

Palacký University
Centre of the Region Haná for Biotechnological and Agricultural Research, Czech Republic
Leibniz Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben, Germany

Increased shoot branching. The number of side branches is very important to plant architecture, which influences the yield and quality of the plant.
( Chen et al., 2023 )

SDN1
CRISPR/Cas

Zhejiang University
Ministry of Agriculture and Rural Affairs of China, China

Improvement of grain weight. Longer panicle.
( Xu et al., 2016 )

SDN1
CRISPR/Cas

China National Rice Research Institute, China
China Three Gorges University, China

Early flowering time. Flowering time (heading date) is an important trait for crop yield and cultivation.
( Yin et al., 2023 )

SDN1
CRISPR/Cas

Shenyang Agricultural University, China

Butterhead plant architecture.
( Xie et al., 2023 )

SDN1
CRISPR/Cas

Huazhong Agricultural University
Wuhan Academy of Agricultural Sciences, China

Enhanced performance of soybean under dense conditions.
( Ji et al., 2022 )

SDN1
CRISPR/Cas

Academy of Agricultural Sciences
Southern University of Science and Technology, China

Increased grain size and modulated shoot architecture.
( Miao et al., 2020 )

SDN1
CRISPR/Cas

Zhejiang A&
F University
Nanchang University
Chinese Academy of Sciences, China
Purdue University, USA

SDN1
CRISPR/Cas

South China Agricultural University, China

Increased grain yield and quality.
( Luo et al., 2024 )

SDN1
CRISPR/Cas

Guizhou University, China
King Saud University, Saudi Arabia

Improved rice photosynthetic efficiency and yield: increased light saturation points, stomatal conductance, light tolerance and photosynthetic yields.
(Ye et al., 2021)

SDN1
CRISPR/Cas

South China Agricultural University, China

Increased rice grain size and yield.
( Wang et al., 2022 )

SDN1
CRISPR/Cas

China National Seed Group Co. Ltd., China

Reduced seed dormancy: rapid and uniform germination of seeds is important for rice production. Mutant seeds began to germinate 1 day after sowing, while WT seeds needed 2 days.
(Jung et al., 2019)

SDN1
CRISPR/Cas

Hankyong National University
Chungbuk National University
Hanyang University, China
Central Luzon State University, Philippines

Early bolting and flowering.
( Wang et al., 2023 )

SDN1
CRISPR/Cas

South China Agricultural University, China

Increased grain yield when grown at low latitudes.
( Song et al., 2024 )

SDN1
CRISPR/Cas

Zhejiang Academy of Agricultural Sciences
Zhejiang A&
F University, China

Improved lodging resistance in later growth stages due to shorter plant height with enhanced resistance to rice blast.
( Gang et al., 2023 )

SDN1
CRISPR/Cas

Huaiyin Institute of Agricultural Science/Huai'
an Key Laboratory of Agricultural Biotechnology
Huaiyin Normal University
China National Rice Research Institute, China

Control flowering time, an important determinant for soybean yield and adaptation.
( Li et al., 2020 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences
University of Chinese Academy of Sciences
Guangzhou University
Agronomy College of Heilongjiang Bayi Agricultural University
Nanjing Agricultural University
Heilongjiang Academy of Agricultural Sciences, China

Increased grain size.
( Chen et al., 2020 )

SDN1
CRISPR/Cas

China National Rice Research Institute
Huazhong Agricultural University
Nanchong Academy of Agricultural Sciences, China

Early flowering phenotype with no adverse effect on yield.
( Shang et al., 2023 )

SDN1
CRISPR/Cas

Huazhong Agricultural University
Hubei Hongshan Laboratory
Chinese Academy of Agricultural Sciences, China
University of Nottingham, UK

Range of beneficial phenotypes: additional tillers and smaller culms and panicles.
(Cui et al., 2020)

SDN1
CRISPR/Cas

China National Rice Research Institute
Huazhong Agricultural University, China
Yangzhou University, Nagoya University, Japan

Traits categories

Genome Editing Technique

Countries

Plant

Sdn Type

Traits related to biotic stress tolerance

Traits related to improved food/feed quality

Traits related to increased plant yield and growth