genome search | EU-SAGE

Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 28 results

Traits related to biotic stress tolerance

Fungal resistance: enhanced resistance against powdery mildew disease.
(Xu et al., 2023)

SDN1
CRISPR/Cas

Kyungpook National University
Rural Development Administration
Sunchon National University, South Korea
Lingnan Normal University, China

Enhanced resistance to insects, no serotonin production and higher salicylic acid levels. Rice brown planthopper (BPH; Nilaparvata lugens Stål) and striped stem borer (SSB; Chilo suppressalis) are the two most serious pests in rice production.
( Lu et al., 2018 )

SDN1
CRISPR/Cas

Zhejiang University
Jiaxing Academy of Agricultural Sciences
Wuxi Hupper Bioseed Ltd.
Hubei Collaborative Innovation Center for Grain Industry, China
Newcastle University, UK

Viral and fungal resistance: Tomato yellow leaf curl virus (TYLCV) and powdery mildew (Oidium neolycopersici), diseases which reduce tomato crop yields and cause substantial economic losses each year.
(Pramanik et al., 2021)

SDN1
CRISPR/Cas

Gyeongsang National University
Pusan National University
R&
D Center, Bunongseed Co., South Korea

Fungal resistance: improved resistance to necrotrophic fungus Botrytis cinerea.
(Jeon et al., 2020)

SDN1
CRISPR/Cas

Stanford University, UK
L’Oreal, France
Howard Hughes Medical Institute, USA

Bacterial resistance: Increased resistance to Erwinia amylovora, causing fire blight disease that threatens the apple and a wide range of ornamental and commercial Rosaceae host plants.
(Malnoy et al., 2016)

SDN1
CRISPR/Cas

Fondazione Edmund Mach, Italy
ToolGen Inc.
Institute for Basic Science
Seoul National University, South Korea

Fungal and bacterial resistance: increased resistance towards the bacterial pathogen Pseudomonas syringae pv. maculicola (Psm) and fungal pathogen Alternaria brassicicola.
(Yung Cha et al., 2023)

SDN1
CRISPR/Cas

Gyeongsang National University, South Korea

Bacterial resistance: enhanced resistance to Xanthomonas oryzae, causing bacterial blight, a devastating rice disease resulting in yield losses.
(Kim et al., 2019)

SDN1
CRISPR/Cas

Sejong University, South Korea

Fungal resistance: resistance to Oidium neolycopersici, causing powdery mildew.
(Nekrasov et al., 2017)

SDN1
CRISPR/Cas

Max Planck Institute for Developmental Biology, Germany
Norwich Research Park, UK

Viral resistance: increased resistance to turnip mosaic virus (TuMV).
(Lee et al., 2023)

SDN1
CRISPR/Cas

Rural Development Administration
Advanced Institute for Science and Technology, South Korea
North Carolina State University, USA

Herbicide resistance: pds (phytoene desaturase), ALS (acetolactate synthase), and EPSPS (5-Enolpyruvylshikimate-3-phosphate synthase)
(Yang et al., 2022)

SDN1
CRISPR/Cas

Chonnam National University, South Korea

Viral resistance: enhanced Potato virus Y (PVY) resistance. PVY infection can result in up to 70% yield loss globally.
(Le et al., 2022)

SDN1
CRISPR/Cas

Vietnam Academy of Science and Technology, Vietnam
University of Edinburgh, UK

Bacterial resistance: Enhanced resistance against hemibiotrophic pathogens M. oryzae and Xanthomonas oryzae pv. oryzae (but increased susceptibility to Cochliobolus miyabeanus)
(Kim et al., 2022)

SDN1
CRISPR/Cas

Seoul National University
Kyung Hee University, South Korea
Pennsylvania State University, USA

Mutants were compromised in infectivity of Phytophthora palmivora, a destructive oomycete plant pathogen with a wide host range
( Pettongkhao et al., 2022 )

SDN1
CRISPR/Cas

Prince of Songkla University, Thailand
University of Hawaii at Manoa
East-West Center, USA
Sainsbury Laboratory Cambridge University (SLCU), UK

Bacterial resistance: Resistance to Pseudomonas syringae DC3000, a widespread pathogen that causes bacterial speck disease of tomato.
(Ortigosa et al., 2019)

SDN1
CRISPR/Cas

Centro Nacional de Biotecnología, Consejo Superior de Investigaciones CientÃficas (CNB-CSIC),Spain

Viral resistance: resistance to pepper mottle virus (PepMoV), causing considerable damage to crop plants.
(Yoon et al., 2020)

SDN1
CRISPR/Cas

Seoul National University
National Institute of Horticultural and Herbal Science, South Korea

Fungal resistance: increased resistance to Erysiphe necator, causing powdery mildew in grape cultivar. The pathogen infects all green tissues and berries, leading to dramatic losses in yield and berry quality.
(Malnoy et al., 2016)

SDN1
CRISPR/Cas

Fondazione Edmund Mach, Italy
ToolGen Inc.
Institute for Basic Science
Seoul National University, South Korea

Traits related to herbicide tolerance

Dinitroanaline
( Liu et al., 2021 )

Chinese Academy of Agricultural Sciences
China Agricultural University
Zhejiang University
Scientific Observing and Experimental Station of Crop Pests in Guilin, Ministry of Agriculture and Rural Affairs, China
Norwegian Institute of Bioeconomy Research, Norway

Bispyribac sodium
( Kuang et al., 2020 )

Chinese Academy of Agricultural Sciences
China Agricultural University
Zhejiang University, China
Norwegian Institute of Bioeconomy Research, Norway

Traits related to storage performance

Decreased postharvest water loss with a 17–30% increase in wax accumulation.
( Chen et al., 2023 )

SDN1
CRISPR/Cas

China Agricultural University
Chinese Academy of Sciences, China
University of Nottingham, UK

Improved shelf-life with improved or not affected sugar: acid ratio, aroma volatiles, and skin color.
(Ortega-Salazar et al., 2023)

SDN1
CRISPR/Cas

University of California, USA
Zhejiang Normal University, China
University of Nottingham, UK

Improved strawberry fruit firmness. The postharvest shelf life is highly limited by the loss of firmness, making firmness one of the most important fruit quality traits.
( López-Casado et al., 2023 )

SDN1
CRISPR/Cas

Universidad de Málaga
Universidad de Córdoba, Spain

Improved shelf-life by targeting the genes modulating pectin degradation in ripening tomato.
( Wang et al., 2019 )

SDN1
CRISPR/Cas

University of London
University of Leicester
University of Nottingham
University of Leeds, UK
International Islamic University Malaysia, Malaysia
Shanxi Academy of Agricultural Sciences, China
University of California, USA

Enhanced storage potential of ripening fruits.
( Do et al., 2024 )

SDN1
CRISPR/Cas

Kyungpook National University
Sunchon National University
Catholic University of Korea, South Korea

Reduced fruit flesh browning. The browning of eggplant berry flesh after cutting has a negative impact on fruit quality for both industrial transformation and fresh consumption.
( Maioli et al., 2020 )

SDN1
CRISPR/Cas

University of Torino, Italy
Instituto de Biologica Molecular y Celular de Plantas (IBMCP)
Universitat Politècnica de València, Spain

Enhancement of flowering time. Petunia has become popular in the floriculture industry, however it is sensitive to ethylene, which causes flower senescence.
( Xu et al., 2021 )

SDN1
CRISPR/Cas

Kyungpook National University
Kangwon National University, South Korea

Controlling the rate of fruit softening to extend shelf life.
( Uluisik et al., 2016 )

SDN1
CRISPR/Cas

University of Nottingham
Royal Holloway University of London
Heygates Ltd
Syngenta Seeds
Sutton Bonington Campus, UK
Syngenta Crop Protection
University of California
Cornell University
Skidmore College, USA

Delayed onset of riping.
( Jeon et al., 2024 )

SDN1
CRISPR/Cas

Kyungpook National University
Sunchon National University, South Korea

Altering tomato fruit ripening and softening, key traits for fleshy fruit. During ripening, fruit will gradually soften which is largely the result of fruit cell wall degradation. Softening may improve the edible quality of fruit but also reduces fruit resistance to pathogenic microorganisms. Fruit softening can cause mechanical damage during storage and transportation as well, which can reduce the storage and shelf life, leading to fruit loss.
( Gao et al., 2021 )

SDN1
CRISPR/Cas

China Agricultural University
South China Agricultural University
Fujian Agriculture and Forestry University
Zhejiang University
Beijing University of Agriculture, China
University of Nottingham, UK

Traits categories

Genome Editing Technique

Countries

Plant

Sdn Type

Traits related to biotic stress tolerance

Traits related to herbicide tolerance

Traits related to storage performance