genome search | EU-SAGE

Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 36 results

Traits related to improved food/feed quality

Reduced cesium content. The production of radiocesium in food in contaminated soils is a serious health concern.
( Nieves-Cordones et al., 2017 )

SDN1
CRISPR/Cas

Université Montpellier, France

Highly specific detection of Ochratoxin A (OTA) in cereal samples. OTA is classified as a Class 2B carcinogens. The method can be flexibly customized to detect a wide range of small molecular targets and holds great promise as a versatile sensing kit with applications in various fields requiring sensitive and specific detection of diverse analytes.
( Chen et al., 2023 )

SDN1
CRISPR/Cas

Ningbo University
Hainan University
Ningbo Clinical Pathology Diagnosis Center, China
University of New South Wales, Australia

Changing grain composition: decrease in the prolamines, an increase in the glutenins, increased starch content, amylose content, and β-glucan content. The protein matrix surrounding the starch granules was increased.
(Yang et al., 2020)

SDN1
CRISPR/Cas

Sichuan Agricultural University, China
Norwich Research Park, UK
CSIRO Agriculture and Food, Australia

Reduced flavonoids and improved fatty acid composition with higher linoleic acid and linolenic acid, valuable for rapeseed germplasm and breeding. The genetic improvement has great significance in the economic value of rapeseeds.
( Xie et al., 2020 )

SDN1
CRISPR/Cas

Yangzhou University
The Ministry of Education of China, China
University of Western Australia, Australia

Reduce allergen proteins. Structural and metabolic proteins, like α-amylase/trypsin inhibitors are involved in the onset of wheat allergies (bakers' asthma) and probably Non-Coeliac Wheat Sensitivity (NCWS).
( Camerlengo et al., 2020 )

SDN1
CRISPR/Cas

University of Tuscia, Italy
Rothamsted Research, UK
Impasse Thérèse Bertrand-Fontaine, France

Increased levels of oleic acid, decreased levels of fatty acids.
( Morineau et al., 2016 )

SDN1
CRISPR/Cas

Université Paris-Saclay, France

Altered starch properties. Changes in amylopectin chain-lengths, starch granule initiation and branching frequency.
( Tuncel et al., 2019 )

SDN1
CRISPR/Cas

Norwich Research Park, UK

Low glutelin content in the rice germplasm: patients with chronic kidney disease (CKD) and phenylketonuria (PKU) need to eat rice with low glutelin content.
(Chen et al., 2022)

SDN1
CRISPR/Cas

Nanjing Branch of Chinese National Center for Rice Improvement
Yangzhou University
Henan Agricultural University
Jiangsu Academy of Agricultural Sciences, China
CSIRO Agriculture and Food, Australia

Increased grain number per spikelet.
( Zhang et al., 2019 )

SDN1
CRISPR/Cas

University of Missouri
South Dakota State University
University of California
Donald Danforth Plant Science Center, USA
University of Bristol, UK

Specific differences in grain morphology, composition and (1,3;1,4)-β-glucan content. Barley rich in (1,3;1,4)-β-glucan, a source of fermentable dietary fibre, is useful to protect against various human health conditions. However, low grain (1,3;1,4)-β-glucan content is preferred for brewing and distilling.
( Garcia-Gimenez et al., 2020 )

SDN1
CRISPR/Cas

The James Hutton Institute
University of Dundee, UK
University of Adelaide
La Trobe University, Australia

Reduced browning and acrylamide. Acrylamide is a contaminant which forms during the baking, toasting and high-temperature processing of foods and is regarded as a potential carcinogen and neurotoxin.
( Nguyen Phuoc Ly et al., 2023 )

SDN1
CRISPR/Cas

Murdoch University, Australia

Increased iron (Fe) and magnesium (Mn) content for biofortification: increasing the intrinsic nutritional value of crops.
(Connorton et al., 2017)

SDN1
CRISPR/Cas

John Innes Centre
University of East Anglia, UK

Fine-tuning the amylose content, one of the major contributors to the eating and cooking quality.
( Xu et al., 2021 )

Jiangsu Academy of Agricultural Sciences/Nanjing Branch of Chinese National Center for Rice Improvement
Yangzhou University
Chinese Academy of Sciences, China
CSIRO Agriculture and Food, Australia

Production of opaque seeds with depleted starch reserves. Reduced starch content and increased amylose content. Accumulation of multiple sugars, fatty acids, amino acids and phytosterols.
( Baysal et al., 2020 )

SDN1
CRISPR/Cas

University of Lleida-Agrotecnio Center
Catalan Institute for Research and Advanced Studies (ICREA), Spain
Royal Holloway University of London, UK

Enhancing the accumulation of eicosapentaenoic acid and docosahexaenoic acid, essential components of a healthy, balanced diet.
( Han et al., 2022 )

SDN1
CRISPR/Cas

Rothamsted Research, UK
Montana State University, USA

Reduced amount of saturated fatty acids (FA) in soybean seeds for nutrititional improvement. FA are linked to cardiovascular diseases.
( Ma et al., 2021 )

SDN1
CRISPR/Cas

Zhejiang University, China
La Trobe University, Australia

Reduced accumulation of free asparagine, the precursor for acrylamide. Acrylamide is a contaminant which forms during the baking, toasting and high-temperature processing of foods made from wheat.
( Raffan et al., 2021 )

SDN1
CRISPR/Cas

Rothamsted Research
University of Bristol, UK

Traits related to increased plant yield and growth

Larger fruits with more locules and larger shoot apical meristem.
( Song et al., 2022 )

SDN1
CRISPR/Cas

South China Agricultural University, China
University of Toulouse, France

Dwarf phenotype.
( Lawrenson et al., 2015 )

SDN1
CRISPR/Cas

Norwich Research Park, UK
Murdoch University, USA

Early-flowering varieties. The timing of flowering is an important event in the life cycle of flowering plants.
( Jiang et al., 2018 )

SDN1
CRISPR/Cas

Hunan Agricultural University, China
Université de Strasbourg, France

More flowers in both determinate and indeterminate cultivars and more produced fruit.
( Hu et al., 2022 )

SDN1
CRISPR/Cas

Université de Toulouse
Université Bordeaux, France
Chongqing University, China

Semi-dwarf phenotype to improve lodging resistance and increased seed dormancy. Increased seed dormancy can be beneficial for use in the malting industry.
( Cheng et al., 2023 )

SDN1
CRISPR/Cas

University of Tasmania
Murdoch University
Department of Primary Industries and Regional Development, Australia
Chinese Academy of Agricultural Sciences, China

Dwarf phenotype. Tomatoes with compact growth habits and reduced plant height can be useful in some environments.
( Tomlinson et al., 2019 )

SDN1
CRISPR/Cas

Norwich Research Park, UK
University of Minnesota, USA

Regulated inflorescence and flower development. More flowers and more fruit produced upon vibration-assisted fertilization.
( Hu et al., 2022 )

SDN1
CRISPR/Cas

Université de Toulouse, France
Chongqing University, China

Early flowering phenotype with no adverse effect on yield.
( Shang et al., 2023 )

SDN1
CRISPR/Cas

Huazhong Agricultural University
Hubei Hongshan Laboratory
Chinese Academy of Agricultural Sciences, China
University of Nottingham, UK

Early flowering. Certain mutants also showed following phenotypes: determinate flowering, shorter stature and/or basal branching.
(Bellec et al., 2022)

SDN1
CRISPR/Cas

Université Paris-Saclay, France

Increase in plant height, tiller number, grain protein content and yield. 1.5- to 2.8-fold increase in total chlorophyll content in the flag leaf at the grain filling stage. Delayed senescence by 10–14 days. High nitrogen content in shoots under low nitrogen conditions.
( Karunarathne et al., 2022 )

SDN1
CRISPR/Cas

Murdoch University
Department of Primary Industries and Regional Development, Australia

Positive regulation for grain dormancy. Lack of grain dormancy in cereal crops causes losses in yield and quality because of preharvest sprouting.
( Lawrenson et al., 2015 )

SDN1
CRISPR/Cas

Norwich Research Park, UK
Murdoch University, Australia

Control meristem size to increase fruit yield.
( Yuste-Lisbona et al., 2020 )

SDN1
CRISPR/Cas

Universidad de Almería
Universitat Politècnica de València–Consejo Superior de Investigaciones Científicas
Spain
Max Planck Institute for Plant Breeding Research
Thünen Institute of Forest Genetics, Germany
Université Paris-Saclay, France

Altered spike architecture.
( de Souza Moraes et al., 2022 )

SDN1
CRISPR/Cas

Wageningen University and Research, The Netherlands
Universidade de São Paulo, Brazil
Norwich Research Park, UK
Rheinische Friedrich-Wilhelms-Universität, Germany

Increased water use efficiency without growth reductions in well-watered conditions.
( Blankenagel et al., 2022 )

SDN1
CRISPR/Cas

Technical University of Munich
Max Planck Institute of Molecular Plant Physiology
German Research Center for Environmental Health
KWS SAAT SE &
Co.KGaA
Université Technique de Munich
Heinrich Heine University, Germany
LEPSE - Écophysiologie des Plantes sous Stress environnementaux, France

Promote growth of axillary buds. Lateral branches develop from the axillary buds. The number of side branches is very important to plant architecture, which influences the yield and quality of the plant.
( Li et al., 2021 )

SDN1
CRISPR/Cas

Guizhou University
Northwest A&
F University
Shandong Agricultural University
Northeast Agricultural University
Shanxi University, China
Oxford University
University of Bedfordshire, UK

Early flowering. Day-light sensitivity limited the geographical range of cultivation.
( Soyk et al., 2016 )

SDN1
CRISPR/Cas

Cold Spring Harbor Laboratory, USA
Max Planck Institute for Plant Breeding Research, Germany
Université Paris-Scalay, France

Increased pollen activity, subsequently inducing fruit setting.
( Wu et al., 2022 )

SDN1
CRISPR/Cas

South China Agricultural University
Chongqing University, China
Université de Toulouse, France

Regulated sepal growth
( Xing et al., 2022 )

SDN1
CRISPR/Cas

China Agricultural University
Chinese Academy of Sciences
Zhejiang University, China
University of Nottingham, UK

Production of enlarged, dome-shaped leaves. Enlarged fruits with increased pericarp thickness due to cell expansion.
( Swinnen et al., 2022 )

SDN1
CRISPR/Cas

Ghent University
Center for Plant Systems Biology, Vives, Belgium
Université de Bordeaux, France

Traits categories

Genome Editing Technique

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Sdn Type

Traits related to improved food/feed quality

Traits related to increased plant yield and growth