Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Genome Editing Technique

Sdn Type

Displaying 45 results

Traits related to biotic stress tolerance

Viral resistance: reduced viral accumulation and amelioration of virus-induced symptoms by Potato Virus Y.
(Lucioli et al., 2022)
SDN1
CRISPR/Cas
ENEA
Council for Agricultural Research and Economics (CREA), Italy
National Agricultural Research and Innovation Centre, Hungary
Fungal resistance: improved resistance to necrotrophic fungus Botrytis cinerea.
(Jeon et al., 2020)
SDN1
CRISPR/Cas
Stanford University, UK
L’Oreal, France
Howard Hughes Medical Institute, USA
Rapid and on-site detection of the mycotoxin zearalenone.
( Pei et al., 2024 )
SDN1
CRISPR/Cas
Shaanxi University of Science and Technology
Anhui Agricultural University
China National Center for Food Safety Risk Assessment, China
Queen'
s University Belfast, UK
Fungal resistance: resistance to Oidium neolycopersici, causing powdery mildew.
(Nekrasov et al., 2017)
SDN1
CRISPR/Cas
Max Planck Institute for Developmental Biology, Germany
Norwich Research Park, UK
Viral resistance: enhanced Potato virus Y (PVY) resistance. PVY infection can result in up to 70% yield loss globally.
(Le et al., 2022)
SDN1
CRISPR/Cas
Vietnam Academy of Science and Technology, Vietnam
University of Edinburgh, UK
Bacterial resistance: Strong resistance to Xanthomonas oryzae, causing bacterial blight, a devastating rice disease resulting in yield losses.
(Wang et al., 2017)
SDN1
TALENs
National University of Singapore, Singapore
Viral resistance: resistance to rice tungro spherical virus, causing rice tungro disease (RTD). RTD is a serious threat for rice production in tropical Asia.
(Macovei et al., 2018)
SDN1
CRISPR/Cas
International Rice Research Institute (IRRI), Philippines
Mutants were compromised in infectivity of Phytophthora palmivora, a destructive oomycete plant pathogen with a wide host range
( Pettongkhao et al., 2022 )
SDN1
CRISPR/Cas
Prince of Songkla University, Thailand
University of Hawaii at Manoa
East-West Center, USA
Sainsbury Laboratory Cambridge University (SLCU), UK
Viral resistance: Highly efficient resistance against wheat dwarf virus (WDV), an economically important virus. WDV infect both wheat and barley causing severe yield losses. The natural resistance resources are limited.
(Kis et al., 2019)
SDN1
CRISPR/Cas
University of Pannonia
Hungarian Academy of Sciences
Eötvös Loránd University University
Szent István University, Hungary
Bacterial resistance: improved resistance to Xanthomonas oryzae, which causes bacterial blight, a devastating rice disease resulting in yield losses.
(Oliva et al., 2019)
SDN1
CRISPR/Cas
International Rice Research Institute, Philippines
University of Missouri
University of Florida
Iowa State University
Donald Danforth Plant Science Center, USA
Université Montpellier, France
Heinrich Heine Universität Düsseldorf
Max Planck Institute for Plant Breeding Research
Erfurt University of Applied Sciences, Germany
Nagoya University, Japan
Enhanced resistance to insects, no serotonin production and higher salicylic acid levels. Rice brown planthopper (BPH; Nilaparvata lugens Stål) and striped stem borer (SSB; Chilo suppressalis) are the two most serious pests in rice production.
( Lu et al., 2018 )
SDN1
CRISPR/Cas
Zhejiang University
Jiaxing Academy of Agricultural Sciences
Wuxi Hupper Bioseed Ltd.
Hubei Collaborative Innovation Center for Grain Industry, China
Newcastle University, UK

Traits related to improved food/feed quality

Enhancing the accumulation of eicosapentaenoic acid and docosahexaenoic acid, essential components of a healthy, balanced diet.
( Han et al., 2022 )
SDN1
CRISPR/Cas
Rothamsted Research, UK
Montana State University, USA
Reduced accumulation of free asparagine, the precursor for acrylamide. Acrylamide is a contaminant which forms during the baking, toasting and high-temperature processing of foods made from wheat.
( Raffan et al., 2021 )
SDN1
CRISPR/Cas
Rothamsted Research
University of Bristol, UK
Changing grain composition: decrease in the prolamines, an increase in the glutenins, increased starch content, amylose content, and β-glucan content. The protein matrix surrounding the starch granules was increased.
(Yang et al., 2020)
SDN1
CRISPR/Cas
Sichuan Agricultural University, China
Norwich Research Park, UK
CSIRO Agriculture and Food, Australia
Reduce allergen proteins. Structural and metabolic proteins, like α-amylase/trypsin inhibitors are involved in the onset of wheat allergies (bakers' asthma) and probably Non-Coeliac Wheat Sensitivity (NCWS).
( Camerlengo et al., 2020 )
SDN1
CRISPR/Cas
University of Tuscia, Italy
Rothamsted Research, UK
Impasse Thérèse Bertrand-Fontaine, France
Altered starch properties. Changes in amylopectin chain-lengths, starch granule initiation and branching frequency.
( Tuncel et al., 2019 )
SDN1
CRISPR/Cas
Norwich Research Park, UK
Increased grain number per spikelet.
( Zhang et al., 2019 )
SDN1
CRISPR/Cas
University of Missouri
South Dakota State University
University of California
Donald Danforth Plant Science Center, USA
University of Bristol, UK
Specific differences in grain morphology, composition and (1,3;1,4)-β-glucan content. Barley rich in (1,3;1,4)-β-glucan, a source of fermentable dietary fibre, is useful to protect against various human health conditions. However, low grain (1,3;1,4)-β-glucan content is preferred for brewing and distilling.
( Garcia-Gimenez et al., 2020 )
SDN1
CRISPR/Cas
The James Hutton Institute
University of Dundee, UK
University of Adelaide
La Trobe University, Australia
Increased iron (Fe) and magnesium (Mn) content for biofortification: increasing the intrinsic nutritional value of crops.
(Connorton et al., 2017)
SDN1
CRISPR/Cas
John Innes Centre
University of East Anglia, UK
Production of opaque seeds with depleted starch reserves. Reduced starch content and increased amylose content. Accumulation of multiple sugars, fatty acids, amino acids and phytosterols.
( Baysal et al., 2020 )
SDN1
CRISPR/Cas
University of Lleida-Agrotecnio Center
Catalan Institute for Research and Advanced Studies (ICREA), Spain
Royal Holloway University of London, UK

Traits related to increased plant yield and growth

Regulated sepal growth
( Xing et al., 2022 )
SDN1
CRISPR/Cas
China Agricultural University
Chinese Academy of Sciences
Zhejiang University, China
University of Nottingham, UK
Increased grain yield without side effect.
( Gho et al., 2022 )
SDN1
CRISPR/Cas
Kyung Hee University, South Korea
International Rice Research Institute, Philippines
Dwarf phenotype.
( Lawrenson et al., 2015 )
SDN1
CRISPR/Cas
Norwich Research Park, UK
Murdoch University, USA
Reduced seed dormancy: rapid and uniform germination of seeds is important for rice production. Mutant seeds began to germinate 1 day after sowing, while WT seeds needed 2 days.
(Jung et al., 2019)
SDN1
CRISPR/Cas
Hankyong National University
Chungbuk National University
Hanyang University, China
Central Luzon State University, Philippines
Conferred lodging resistance. Tef is a staple food, and valuable cash crop in Ethiopia. Lodging is a major limitation to its production.
( Beyene et al., 2022 )
SDN1
CRISPR/Cas
Donald Danforth Plant Science Center
Corteva Agriscience
Michigan State University, USA
Ethiopian Institute of Agricultural Research, Ethiopia
Dwarf phenotype. Tomatoes with compact growth habits and reduced plant height can be useful in some environments.
( Tomlinson et al., 2019 )
SDN1
CRISPR/Cas
Norwich Research Park, UK
University of Minnesota, USA
Control grain size and seed coat color.
( Tra et al., 2021 )

BE
International Rice Research Institute, Philippines
Dahlem Center of Plant Sciences Freie Universität, Germany
Synthetic Biology, Biofuel and Genome Editing R&
D Reliance Industries Ltd, India
Early flowering phenotype with no adverse effect on yield.
( Shang et al., 2023 )
SDN1
CRISPR/Cas
Huazhong Agricultural University
Hubei Hongshan Laboratory
Chinese Academy of Agricultural Sciences, China
University of Nottingham, UK
Positive regulation for grain dormancy. Lack of grain dormancy in cereal crops causes losses in yield and quality because of preharvest sprouting.
( Lawrenson et al., 2015 )
SDN1
CRISPR/Cas
Norwich Research Park, UK
Murdoch University, Australia
Altered spike architecture.
( de Souza Moraes et al., 2022 )
SDN1
CRISPR/Cas
Wageningen University and Research, The Netherlands
Universidade de São Paulo, Brazil
Norwich Research Park, UK
Rheinische Friedrich-Wilhelms-Universität, Germany
Improved spikelet number per panicle led to increased grain yield per plant.
( Ludwig et al., 2023 )
SDN1
CRISPR/Cas
International Rice Research Institute (IRRI), Philippines
University of Pavia, Italy
Promote growth of axillary buds. Lateral branches develop from the axillary buds. The number of side branches is very important to plant architecture, which influences the yield and quality of the plant.
( Li et al., 2021 )
SDN1
CRISPR/Cas
Guizhou University
Northwest A&
F University
Shandong Agricultural University
Northeast Agricultural University
Shanxi University, China
Oxford University
University of Bedfordshire, UK

Traits related to industrial utilization

Conversion of hulled into naked barley.
( Gasparis et al., 2018 )
SDN1
CRISPR/Cas
National Research Institute
Warsaw University of Life Sciences (SGGW), Poland
Hairy root transformation. Hairy roots play a role in multiple processes, ranging from recombinant protein production and metabolic engineering to analyses of rhizosphere physiology and biochemistry.
( Ron et al., 2014 )
SDN1
CRISPR/Cas
University of California
Emory University, USA
University of Cambridge, UK
New red-grained and pre-harvest sprouting (PHS)-resistant wheat varieties with elite agronomic traits. PHS reduces yield and grain quality, additionally the red pigment of the grain coat contains proanthocyanidins, which have antioxidant activity and thus health-promoting properties.
( Zhu et al., 2022 )
SDN1
CRISPR/Cas
Chinese Academy of Agricultural Sciences
Fujian Academy of Agricultural Sciences
Henan University
Shenzhen Research Institute of Henan university
Taiyuan University of Technology
Southern University of Science and Technology, China
University of Edinburgh, UK

Traits related to product color/flavour

Improved aroma, flavour and fatty acid (FA) profiles of pea seeds.
( Bhowmik et al., 2023 )
SDN1
CRISPR/Cas
National Research Council Canada (NRC)
University of Calgary
University of Saskatchewan
Agriculture and Agri-Food Canada (AAFC)
St. Boniface Hospital Research, Canada
John Innes Centre, UK
Color modification due to reduced anthocyanin accumulation.
( Klimek-Chodacka et al., 2018 )
SDN1
CRISPR/Cas
University of Agriculture in Krakow, Poland
East Carolina University
University of Maryland, USA
Albino phenotype.
( Wilson et al., 2019 )
SDN1
CRISPR/Cas
NIAB EMR, UK
Albino phenotype.
( Wilson et al., 2019 )
SDN1
CRISPR/Cas
NIAB EMR, UK
Albino phenotype
( Bánfalvi et al., 2020 )
SDN1
CRISPR/Cas
NARIC Agricultural Biotechnology Institute, Hungary

Traits related to storage performance

Improved shelf-life by targeting the genes modulating pectin degradation in ripening tomato.
( Wang et al., 2019 )
SDN1
CRISPR/Cas
University of London
University of Leicester
University of Nottingham
University of Leeds, UK
International Islamic University Malaysia, Malaysia
Shanxi Academy of Agricultural Sciences, China
University of California, USA
Controlling the rate of fruit softening to extend shelf life.
( Uluisik et al., 2016 )
SDN1
CRISPR/Cas
University of Nottingham
Royal Holloway University of London
Heygates Ltd
Syngenta Seeds
Sutton Bonington Campus, UK
Syngenta Crop Protection
University of California
Cornell University
Skidmore College, USA
Decreased postharvest water loss with a 17–30% increase in wax accumulation.
( Chen et al., 2023 )
SDN1
CRISPR/Cas
China Agricultural University
Chinese Academy of Sciences, China
University of Nottingham, UK
Altering tomato fruit ripening and softening, key traits for fleshy fruit. During ripening, fruit will gradually soften which is largely the result of fruit cell wall degradation. Softening may improve the edible quality of fruit but also reduces fruit resistance to pathogenic microorganisms. Fruit softening can cause mechanical damage during storage and transportation as well, which can reduce the storage and shelf life, leading to fruit loss.
( Gao et al., 2021 )
SDN1
CRISPR/Cas
China Agricultural University
South China Agricultural University
Fujian Agriculture and Forestry University
Zhejiang University
Beijing University of Agriculture, China
University of Nottingham, UK
Improved shelf-life with improved or not affected sugar: acid ratio, aroma volatiles, and skin color.
(Ortega-Salazar et al., 2023)
SDN1
CRISPR/Cas
University of California, USA
Zhejiang Normal University, China
University of Nottingham, UK