genome search | EU-SAGE

Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 59 results

Traits related to biotic stress tolerance

Reduced aphid damage to improve crop resistance to aphids or other insects. Restrict aphid sucking on watermelon.
( Li et al., 2021 )

SDN1
CRISPR/Cas

Beijing Academy of Agricultural and Forestry Sciences, China

High level of powdery mildew resistance while maintaining normal crop
growth and yields.
( Li et al., 2022 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences, China

Robust rust resistance to pandemic stripe rust caused by Puccinia striiformis (Pst) without growth and yield penalty.
( Wang et al., 2022 )

SDN1
CRISPR/Cas

Northwest A&
F University
Chinese Academy of Sciences, China

Viral resistance: increased resistance against wheat yellow mosaic virus (WYMV) without yield penalty. WYMV results in severe yield losses in hexaploid wheat.
(Kan et al., 2023)

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences (CAAS)
Agricultural Sciences Institute in Jiangsu Lixiahe Area, China

Fungal resistance: increased resistance against the fungus Puccinia striiformis f. sp. tritici (Pst). Wheat stripe rust is caused by Pst and is one of the most destructive wheat diseases, resulting in significant losses to wheat production worldwide.
(He et al., 2022)

SDN1
CRISPR/Cas

Northwest A&
F University
Hebei Agri cultural University, China

Fungal resistance: Fusarium oxysporum f.sp. niveum (FON), one of the most devastaging diseases affecting watermelons. FON progresses along xylem vessels, causing the hollow and dried-out stems.
(Zhang et al., 2020)

SDN1
CRISPR/Cas

Jiangsu Academy of Agricultural Sciences
Jiangsu Key Laboratory for Horticultural Crop Genetic Improvement, China

Fungal resistance to Oidium neolycopersici, causing powdery mildew, one of the most important diseases limiting the production of wheat.
( Zhang et al., 2017 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences, China

Fungal resistance: resistance to Fusarium graminearum. Fusarium head blight (FHB) is an economically important disease, affecting both yield and grain quality of maize, wheat and barley.
(Brauer et al., 2020)

SDN1
CRISPR/Cas

Ottawa Research and Development Centre, Canada

Viral resistance: Strong barley yellow dwarf virusses (BYDV) resistance without negative effects on plant growth under field conditions. BYDV threatens efficient and stable production of wheat, maize, barley and oats.
(Wang et al., 2023)

SDN1
CRISPR/Cas

Henan Agricultural University
The Shennong Laboratory
Chinese Academy of Agricultural Sciences, China

Fungal resistance: stripe rust resistance, caused by Puccinia striiformis f. sp. tritici. In appropriate environmental conditions and susceptible varieties, stripe rust can cause huge grain yield and quality loss.
(Li et al., 2023)

SDN1
CRISPR/Cas

Fudan University
Chinese Academy of Sciences
University of the Chinese Academy of Sciences
China Agricultural University
Guangzhou University
School of Life Science
Shandong Academy of Agricultural Sciences
Ministry of Agriculture
National Engineering Research Center for Wheat and Maize
Sichuan Agricultural University
Nanjing Agricultural University, China
Université Paris Cité
Université Paris-Saclay, France

Sensitive and specific visual detection method for Acidovorax citrulli, an important seed-borne disease of the cucurbits.
( Wang et al., 2024 )

SDN1
CRISPR/Cas

Fuyang Normal University
Anhui Jianzhu University
Southern Subtropicals Grops Research Institute, China

Fungal resistance: enhanced resistance against rust caused by Puccinia striiformis f. sp. tritici and powdery mildew caused by Blumeria graminis f. sp. tritici., while also increasing yield.
(Liu et al., 2024)

SDN1
CRISPR/Cas

Southwest University
Yangtze University, China
University of Cologne, Germany
University of Maryland

Viral resistance: enhanced resistance against wheat dwarf virus, which is a causal agent of wheat viral disease and can significantly impact wheat production worldwide.
(Yuan et al., 2024)

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Northwest A&
F University, China

Norwegian Institute of Bioeconomy Research, Norway

Traits related to abiotic stress tolerance

Drought tolerance.
( Kim D et al,. 2018 )

SDN1
CRISPR/Cas

Montana State University, USA

Reduced cuticle permeability and enhanced drought tolerance.
( He et al., 2022 )

SDN1
CRISPR/Cas

Northwest A&
F University
USA
University of British Columbia, Canada

Increased drought tolerance.
( Abdallah et al., 2022 )

SDN1
CRISPR/Cas

Cairo University, Egypt
Crop Improvement and Genetics Unit, USA

Reduced arsenic content and increased arsenic tolerance. Arsenic is toxic to organisms and elevated its accumulation may pose health risks to humans.
( Wang et al., 2023 )

SDN1
CRISPR/Cas

Henan Agricultural University
Chinese Academy of Sciences
Henan Agricultural University, China

Increased root length, which can restore good performance under water stress.
( Gabay et al., 2023 )

SDN1
CRISPR/Cas

University of California
Howard Hughes Medical Institute, USA
University of Haifa, Israel
Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET)
Universidad Nacional de San Martín (UNSAM), Argentina
Fudan University
China Agricultural University, China
Karolinska Institutet, Sweden

Enhanced drought tolerance.
( Wang et al., 2023 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China
International Maize and Wheat Improvement Center, Mexico

Traits related to improved food/feed quality

Altered gliadin levels resulting in improved end-use quality and reduced gluten epitopes associated with celiac disease. Gliadins are important for wheat end-use traits.
( Liu et al., 2023 )

SDN1
CRISPR/Cas

China Agricultural University, China
Research Centre for Cereal and Industrial Crops, Italy

Increased sucrose content.
( Ren et al., 2020 )

SDN1
CRISPR/Cas

Beijing Key Laboratory of Vegetable Germplasm Improvement
Capital Normal University
China Agricultural University, China
Cornell University
Robert W. Holley Center for Agriculture and Health, USA

Reduces phytic acid (anti-nutrient) and improves iron and zinc accumulation in wheat grains. Biofortification.
( Ibrahim et al., 2021 )

SDN1
CRISPR/Cas

Quaid-i-Azam University Islamabad
National Agricultural Research Centre, Pakistan

Decreased seed size and promoted seed germination. To improve consumer experience for flesh-consumed watermelons, no (or small and sparse) seeds are better because the flesh portion is larger.
( Wang et al., 2021 )

SDN1
CRISPR/Cas

Beijing Key Laboratory of Vegetable Germplasm Improvement, China

Increased protein content and increased grain weight. Increase in grain protein content has a positive effect on flour protein content and gluten strength, two quality parameters.
( Zhang et al., 2018 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences
University of Chinese Academy of Sciences
Shandong Normal University, China

Reduced gluten content. Coeliac disease is an autoimmune disorder triggered in genetically predisposed individuals by the ingestion of gluten proteins.
( Sánchez-León,et al., 2017 )

SDN1
CRISPR/Cas

Instituto de Agricultura Sostenible (IASCSIC), Spain
University of Minnesota, USA

Modification of starch composition, structure and properties. Foods with a high amylose content (AC) and resistant starch (RS) offer potential to improve human health and lower the risk of serious non-infectious diseases.
( Li et al., 2020 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences (CAAS)
Nanjing Agricultural University, China

Increased iron (Fe) and magnesium (Mn) content for biofortification: increasing the intrinsic nutritional value of crops.
(Connorton et al., 2017)

SDN1
CRISPR/Cas

John Innes Centre
University of East Anglia, UK

Increased grain number per spikelet.
( Zhang et al., 2019 )

SDN1
CRISPR/Cas

University of Missouri
South Dakota State University
University of California
Donald Danforth Plant Science Center, USA
University of Bristol, UK

Reduce allergen proteins. Structural and metabolic proteins, like α-amylase/trypsin inhibitors are involved in the onset of wheat allergies (bakers' asthma) and probably Non-Coeliac Wheat Sensitivity (NCWS).
( Camerlengo et al., 2020 )

SDN1
CRISPR/Cas

University of Tuscia, Italy
Rothamsted Research, UK
Impasse Thérèse Bertrand-Fontaine, France

Reduced accumulation of free asparagine, the precursor for acrylamide. Acrylamide is a contaminant which forms during the baking, toasting and high-temperature processing of foods made from wheat.
( Raffan et al., 2021 )

SDN1
CRISPR/Cas

Rothamsted Research
University of Bristol, UK

Traits related to increased plant yield and growth

Altered spike architecture and grain treshability to increase grain production.
( Liu et al., 2020 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China

Bigger grains, increased grain weight.
( Zhang et al., 2018 )

SDN1
CRISPR/Cas

Chinese Academy of Sciences, China

Improvement for larger kernel and yield.
( Ma et al., 2015 )

SDN1
CRISPR/Cas

Northwest A &
F University
Chinese Academy of Agricultural Sciences, China

Increased spikelet number and delayed heading date. Two traits that are crucial and correlated to yield in wheat.
( Chen et al., 2022 )

SDN1
CRISPR/Cas

China Agricultural University, China

Increased yield potential trough improved nitrogen use efficiency. Enhanced tolerance to N starvation, and showed delayed senescence and increased grain yield in field conditions. Lowered use of N fertilizer.
( Zhang et al., 2021 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Zhengzhou University, China

Increased grain weight and grain size. Carbohydrate and total protein levels also increased.
( Guo et al., 2021 )

SDN1
CRISPR/Cas

Sichuan Agricultural University, China
University of California, USA

Increased yield: plants produced more tillers and grains than azygous wild-type controls and the total yield was increased up to 15 per cent.
(Holubova et al., 2018)

SDN1
CRISPR/Cas

Palacký University
Centre of the Region Haná for Biotechnological and Agricultural Research, Czech Republic
Leibniz Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben, Germany

Increase in 1000-grain weight, grain area, grain width, grain length, plant height, and spikelets per spike.
( Errum et al., 2023 )

SDN1
CRISPR/Cas

National Agricultural Research Centre (NARC)
PARC Institute of Advanced Studies in Agriculture (PIASA)
Pakistan Agricultural Research Council, Pakistan

Early heading. Heading date is an important agronomic trait that affects climatic adaptation and yield potential.
( Fan et al., 2023 )

SDN1
CRISPR/Cas

Henan Agricultural University, China

Enhanced grain yield and semi-dwarf phenotype by manipulating brassinosteroid signal pathway.
( Song et al., 2023 )

SDN1
CRISPR/Cas

China Agricultural University, China
Hard Winter Wheat Genetics Research Unit, USA

Altered root architecture with increased tillers and total grain weight.
( Rahim et al., 2023 )

SDN1
CRISPR/Cas

Quaid-e-Azam University
National Agricultural Research Centre (NARC)
The University of Haripur, Pakistan
King Saud University, Saudi Arabia
Nile University
Ain Shams University, Egypt
Chonnam National University, South Korea

Increased plant height with an earlier heading date.
( Fu et al., 2024 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Henan Normal University
Sichuan Agricultural University
Henan Agricultural University
Shanxi University, China

Dwarfing phenotype.
( Sun et al., 2024 )

SDN1
CRISPR/Cas

Northwest A&
F University
Guangdong Academy of Agricultural Sciences
Shanxi Agricultural University, China

Increased tiller number.
( Awan et al., 2024 )

SDN1
CRISPR/Cas

National Institute for Biotechnology and Genetic Engineering
Quaid-i-Azam University, Pakistan

Traits related to industrial utilization

Male sterility.
( Zhang et al., 2021 )

SDN1
CRISPR/Cas

Northwest A&
F University, China

Significantly longer seed dormancy period, may result in reduced pre-harvest sprouting of grains on spikes.
( Abe et al., 2019 )

SDN1
CRISPR/Cas

Institute of Crop Science
Okayama University
Yokohama City University
Institute of Agrobiological Sciences
Obihiro University of Agriculture and Veterinary Medicine, Japan

New red-grained and pre-harvest sprouting (PHS)-resistant wheat varieties with elite agronomic traits. PHS reduces yield and grain quality, additionally the red pigment of the grain coat contains proanthocyanidins, which have antioxidant activity and thus health-promoting properties.
( Zhu et al., 2022 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
Fujian Academy of Agricultural Sciences
Henan University
Shenzhen Research Institute of Henan university
Taiyuan University of Technology
Southern University of Science and Technology, China
University of Edinburgh, UK

Generating male sterility lines (MLS). Using MLS in hybrid seed production reduces costs and ensures high purity of the varieties because it does not produce pollen and has exserted stigmas.
( Zhang et al., 2023 )

SDN1
CRISPR/Cas

Shandong Academy of Agricultural Sciences
Key Laboratory of Wheat Biology and Genetic Improvement on North Yellow and Huai River Valley
National Engineering Laboratory for Wheat and Maize
Chinese Academy of Agricultural Sciences, China

Rapid generation of male sterile (MS) bread wheat. MS is an important tool in creating hybrid crop varieties that provide a yield advantage over traditional varieties by harnessing heterosis.
( Singh et al., 2021 )

SDN1
CRISPR/Cas

DuPont Pioneer, USA

Gynoecious phenotype: only female flowers. Advantageous trait for production of hybrid seed by bees under spatial isolation, because it avoids hand emasculation and hand pollination.
(Zhang et al., 2019)

SDN1
CRISPR/Cas

Beijing Key Laboratory of Vegetable Germplasm Improvement
Chinese Academy of Agricultural Engineering Planning and Design, China

SDN1
CRISPR/Cas

Peking University Institute of Advanced Agricultural Sciences
Peking University
Beijing Key Laboratory of Plant Gene Resources and Biotechnology for Carbon Reduction and Environmental Improvement, China

Fertility recovery of male sterility in wheat lines with excelling agronomic and economic traits for breeding purpose, as male-sterile plants cannot be used for selection.
( Tang et al., 2021 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences
China Agricultural University, China

Generation of male-sterile hexaploid wheat lines for use in hybrid seed production. The development and adoption of hybrid seed technology have led to dramatic increases in agricultural productivity.
( Okada et al., 2019 )

SDN1
CRISPR/Cas

The University of Adelaide, Australia
Huaiyin Normal University, China

Complete male sterility. The generation, restoration, and maintenance of male sterile lines are the key issues for large-scale commercial hybrid seed production.
( Li et al., 2020 )

SDN1
CRISPR/Cas

Peking University Institute of Advanced Agricultural Sciences
School of Advanced Agriculture Sciences and School of Life Sciences
Beijing Key Laboratory of Plant Gene Resources and Biotechnology for Carbon Reduction and Environmental Improvement, China

Establishment of maternal haploid induction. Doubled haploid technology is used to obtain homozygous lines in a single generation. This technique significantly accelerates the crop breeding trajectory.
( Tian et al., 2023 )

SDN1
CRISPR/Cas

Beijing Key Laboratory of Vegetable Germplasm Improvement, China

Traits related to herbicide tolerance

Herbicide glyphosate tolerance.
( Arndell et al., 2019 )

SDN1
CRISPR/Cas

CSIRO
New South Wales Department of Primary Industries
The University of Adelaide, Australia

Traits related to product color/flavour

Albino phenotype. Diversity in fruit color. Watermelon is an important fruit croup throughout the world.
( Tian et al., 2016 )

SDN1
CRISPR/Cas

Beijing Key Laboratory of Vegetable Germplasm Improvement
China Agricultural University
Beijing University of Agriculture, China

Traits related to storage performance

The fruit remains green and shows higher firmness as well as no early fermentation. This results in extended shelf-life which could reduce food loss and contribute to food security.
( Nonaka et al., 2023 )

SDN1
CRISPR/Cas

University of Tsukuba, Japan

Delayed fruit ripening.
( Santo Domingo et al., 2024 )

SDN1
CRISPR/Cas

Centre for Research in Agricultural Genomics (CRAG)
Institute for Integrative Systems Biology (I2SysBio)
Institut de Recerca i Tecnologia Agroalimentaries (IRTA), Spain

Traits categories

Genome Editing Technique

Countries

Plant

Sdn Type

Traits related to biotic stress tolerance

Traits related to abiotic stress tolerance

Traits related to improved food/feed quality

Traits related to increased plant yield and growth

Traits related to industrial utilization

Traits related to herbicide tolerance

Traits related to product color/flavour

Traits related to storage performance