genome search | EU-SAGE

Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 32 results

Traits related to biotic stress tolerance

Fungal resistance: increased resistance to Erysiphe necator, causing powdery mildew in grape cultivar. The pathogen infects all green tissues and berries, leading to dramatic losses in yield and berry quality.
(Malnoy et al., 2016)

SDN1
CRISPR/Cas

Fondazione Edmund Mach, Italy
ToolGen Inc.
Institute for Basic Science
Seoul National University, South Korea

High resistance to powdery mildew under semi-commercial growth conditions.
( Shnaider et al., 2022 )

SDN1
CRISPR/Cas

Agricultural Research Organization Volcani Center, Israel

Viral resistance: Resistance against Grapevine leafroll-associated virus 3 (GLRaV-3), which is one of the causal agents of grapevine leafroll disease (GLD). GLD severely impacts grapevine production.
(Jiao et al., 2022)

CRISPR/Cas

Northwest A&
F University, China

Fungal resistance: enhanced resistance to powdery mildew (Erysiphe necator), a major fungal disease, threatening one of the most economically valuable horticular crops.
(Wan et al., 2020)

SDN1
CRISPR/Cas

Ministry of Agriculture, China
Northwest A&
F University
University of Maryland College Park, USA

Virus resistance: Immunity to cucumber vein yellowing virus infection (Ipomovirus) and resistance to the potyviruses Zucchini yellow mosaic virus and Papaya ring spot mosaic virus.
(Chandrasekaran et al., 2016)

SDN1
CRISPR/Cas

Volcani Center, Israel

Bacterial resistance: Xanthomonas citri, causing citrus canker, one of the most serious diseases affecting the global citrus industry. Citrus is the most produced fruit in the world.
(Jia et al., 2016)

SDN1
CRISPR/Cas

University of Florida, USA

Bacterial resistance: resistance to Xanthomonas citri, a pathogen causing citrus canker. Citrus canker is one of the most devastating citrus diseases worldwide, causing canker symptoms. Generating disease-resistant varieties is one of the most efficient and environmentally friendly measures for controlling canker.
(Jia et al., 2021)

SDN1
CRISPR/Cas

University of Florida
Citrus Research and Education Center, USA

Fungal resistance: increased resistance to Botrytis cinerea.
(Wang et al., 2018)

SDN1
CRISPR/Cas

Northwest A&
F University and Ministry of Agriculture, China

Viral resistance: Increased resistance against watermelon mosaic virus (WMV), papaya ringspot virus (PRSV), and zucchini yellow mosaic virus (ZYMV).
(Fidan et al., 2023)

SDN1
CRISPR/Cas

Akdeniz University
Research and Development Department AD ROSSEN Seeds, Turkey

Fungal resistance: effective reduction of susceptibility against downy mildew by increasing salicylic acid levels. The pathogen can devastate individual vineyards and in some cases also affect production from entire regions.
(Giacomelli et al., 2023)

SDN1
CRISPR/Cas

Research and Innovation Centre
Fondazione Edmund Mach, Italy
Enza Zaden
Hudson River Biotechnology, The Netherlands

Fungal resistance: broad-spectrum stress tolerance including Pseudoperonospora cubernsis (P. cubensis) resistance. P. cubensis is the causal agent of cucurbit downy mildew, responsible for devastating losses worldwide of cucumber, cantaloupe, pumpkin, watermelon and squash.
(Dong et al., 2023)

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China
University of California, USA

Fast and accurate field screening and differentiation of four major Tobamoviruses infecting tomato and pepper. Tomatoviruses are the most important viruses infecting plants and cause huge economic losses to tomato and pepper crops globally.
( Zhao et al., 2023 )

SDN1
CRISPR/Cas

Chinese Academy of Inspection and Quarantine
China Agricultural University, China

Fungal resistance: Decreased susceptibility to Plasmopara viticola, the causing agent of the grapevine downy mildew.
(Djennane et al., 2023)

SDN1
CRISPR/Cas

Université de Strasbourg
Institut Jean-Pierre Bourgin (IJPB), France

Fungal resistance: increased resistance against powdery mildew, a destructive disease that threatens cucumber production globally.
(Dong et al., 2023)

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China
University of California Davis, USA
Wageningen University &
Research, The Netherlands

Fungal resistance: reduced symptoms caused by a powedry mildew infection.
(Olivares et al., 2021)

SDN1
CRISPR/Cas

National Institute of Agriculture Research, Chile

Traits related to abiotic stress tolerance

Reduced stomatal density. Intrinsic water-use efficiency was significantly impacted under both well-watered and drought conditions, making reduced stomatal density as a preferable trait.
( Clemens et al., 2022 )

SDN1
CRISPR/Cas

University of California
San Diego State University, USA

Broad-spectrum stress tolerance: enhanced low temperature, salinity, Pseudoperonospora cubensis and water-deficit tolerance.
(Dong et al., 2023)

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China
University of California, USA

Traits related to improved food/feed quality

Low tartaric acid.
( Ren et al., 2016 )

SDN1
CRISPR/Cas

University of Chinese Academy of Sciences
Chinese Academy of Sciences, China

Promoted anthocyanin accumulation. Anthocyanins are plant secondary metabolites with a variety of biological functions.
( Tu et al., 2022 )

SDN1
CRISPR/Cas

Northwest A&
F University, China

Boosted cytokinin biosynthesis and elevated cucumber fruit wart formation. Warty fruit is an important quality trait that greatly affects market value and fruit appearance.
( Wang et al., 2022 )

SDN1
CRISPR/Cas

China Agricultural University, China

Regulate cucumber fruit wart formation. Warty fruit in cucumber is an important quality trait that greatly affects fruit appearance.
( Wang et al., 2021 )

SDN1
CRISPR/Cas

China Agricultural University, China

Fine-tuning sugar content. Consumer preference varies along regional, cultural, and age lines, thus the solution is to create a continuum of phenotypic “taste” changes
( Xing et al., 2020 )

Chinese Academy of Sciences
China Agricultural University, China

Nattokinase (NK) producing cucumber. NK is effective in the prevention and treatment of cardiovascular disease.
( Ni et al., 2023 )

SDN2
CRISPR/Cas

Xuzhou University of Technology
Nankai University, China

Increased phosphorus and anthocyanin content.
( Zhang et al., 2023 )

SDN1
CRISPR/Cas

Shenyang Agricultural University
Ministry of Education, China

Increased phosphorus content and improved fruit quality.
( Zhang et al., 2023 )

SDN1
CRISPR/Cas

Shenyang Agricultural University
Ministry of Education, China

Traits related to increased plant yield and growth

Only female flowers. Allows earlier production of hybrids, higher yield, and more concentrated fruit set.
( Hu et al., 2017 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences,
China

Faster seedling growth.
( Zhou et al., 2018 )

SDN1
CRISPR/Cas

University of Maryland, USA

Increased spine density. The “numerous spines (ns)” cucumber varieties are popular in Europe and West Asia.
( Liu et al., 2022 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China

Transformation of a climbing woody perennial, developing axillary inflorescences after many years of juvenility, into a compact plant with rapid terminal flower and fruit development.
( Varkonyi-Gasic et al., 2022 )

SDN1
CRISPR/Cas

The New Zealand Institute for Plant &
Food Research Limited (Plant &
Food Research), University of Auckland, New Zealand

Traits related to product color/flavour

Albino phenotype.
( Wilson et al., 2019 )

SDN1
CRISPR/Cas

NIAB EMR, UK

Albino phenotype.
( Wang et al., 2018 )

SDN1
CRISPR/Cas

Provincial Key Laboratory of Applied Botany
Guangdong Provincial Key Laboratory of Applied Botany
University of Chinese Academy of Sciences, China

Reduced citrate content. Citrate is a common primary metabolite which often characterizes fruit flavour.
( Fu et al., 2023 )

SDN1
CRISPR/Cas

Zhejiang University, China
University of Florida, USA
The New Zealand Institute for Plant &
Food Research Limited (Plant &
Food Research) Mt Albert
University of Auckland, New Zealand

Traits categories

Genome Editing Technique

Countries

Plant

Sdn Type

Traits related to biotic stress tolerance

Traits related to abiotic stress tolerance

Traits related to improved food/feed quality

Traits related to increased plant yield and growth

Traits related to product color/flavour