genome search | EU-SAGE

Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 36 results

Traits related to biotic stress tolerance

Fungal resistance: increased resistance to Erysiphe necator, causing powdery mildew in grape cultivar. The pathogen infects all green tissues and berries, leading to dramatic losses in yield and berry quality.
(Malnoy et al., 2016)

SDN1
CRISPR/Cas

Fondazione Edmund Mach, Italy
ToolGen Inc.
Institute for Basic Science
Seoul National University, South Korea

Oomycete resistance: significantly reduced susceptibility to downy mildew disease (DM). DM is caused by Peronospora belbahrii, a worldwide threat to the basil industry.
(Zhang et al., 2021)

SDN1
CRISPR/Cas

The State University of New Jersey, USA

Enhanced resistance to downy mildew pathogen.
( Hasley et al., 2021 )

SDN1
CRISPR/Cas

University of Hawaii at Manoa, USA

Viral resistance: Resistance against Grapevine leafroll-associated virus 3 (GLRaV-3), which is one of the causal agents of grapevine leafroll disease (GLD). GLD severely impacts grapevine production.
(Jiao et al., 2022)

CRISPR/Cas

Northwest A&
F University, China

Fungal resistance: enhanced resistance to powdery mildew (Erysiphe necator), a major fungal disease, threatening one of the most economically valuable horticular crops.
(Wan et al., 2020)

SDN1
CRISPR/Cas

Ministry of Agriculture, China
Northwest A&
F University
University of Maryland College Park, USA

Viral resistance: Improved resistance to yellow leaf curl virus, a virus responsible for heavy yield losses for chili peper production.
(Kurniawati et al., 2020)

SDN1
CRISPR/Cas

Institut Pertanian Bogor
Balai Besar Penelitian dan Pengembangan Bioteknologi dan Sumber Daya Genetik Pertanian, Indonesia

Fungal resistance: Resistance to pathogen Colletotrichum truncatum, causing anthracnose, a major disease accounting for significant pre- and post-harvest yield losses.
(Mishra et al., 2021)

SDN1
CRISPR/Cas

Centurion University of Technology and Management
Siksha O Anusandhan University
Rama Devi Women'
s University, India

Fungal resistance: increased resistance to Botrytis cinerea.
(Wang et al., 2018)

SDN1
CRISPR/Cas

Northwest A&
F University and Ministry of Agriculture, China

Oomycete resistance: resistance against downly mildew disease (DM). DM is caused by Peronospora belbahrii, a worldwide threat to the basil industry.
(Laura et al., 2023)

SDN1
CRISPR/Cas

Research Centre for Vegetable and Ornamental Crops
Institute of Agricultural Biology and Biotechnology
Institute for Sustainable Plant Protection
Research Centre for Olive Fruit and Citrus Crops
University of Pisa
Center for Agricultural Experimentation and Assistance
Institute of Biosciences and Bioresources, Italy

Fungal resistance: effective reduction of susceptibility against downy mildew by increasing salicylic acid levels. The pathogen can devastate individual vineyards and in some cases also affect production from entire regions.
(Giacomelli et al., 2023)

SDN1
CRISPR/Cas

Research and Innovation Centre
Fondazione Edmund Mach, Italy
Enza Zaden
Hudson River Biotechnology, The Netherlands

Fungal resistance: Decreased susceptibility to Plasmopara viticola, the causing agent of the grapevine downy mildew.
(Djennane et al., 2023)

SDN1
CRISPR/Cas

Université de Strasbourg
Institut Jean-Pierre Bourgin (IJPB), France

Fungal resistance: reduced symptoms caused by a powedry mildew infection.
(Olivares et al., 2021)

SDN1
CRISPR/Cas

National Institute of Agriculture Research, Chile

Traits related to abiotic stress tolerance

Reduced stomatal density. Intrinsic water-use efficiency was significantly impacted under both well-watered and drought conditions, making reduced stomatal density as a preferable trait.
( Clemens et al., 2022 )

SDN1
CRISPR/Cas

University of California
San Diego State University, USA

Improved drought and salt tolerance.
( Zhang et al., 2023 )

SDN1
CRISPR/Cas

Northeast Forestry University
Chinese Academy of Forestry
Chinese Academy of Sciences
Nanjing Forestry University, China

Traits related to improved food/feed quality

Low tartaric acid.
( Ren et al., 2016 )

SDN1
CRISPR/Cas

University of Chinese Academy of Sciences
Chinese Academy of Sciences, China

Promoted anthocyanin accumulation. Anthocyanins are plant secondary metabolites with a variety of biological functions.
( Tu et al., 2022 )

SDN1
CRISPR/Cas

Northwest A&
F University, China

Enhanced oil composition. Increased oleic acid content and significant decreases in the less desirable polyunsaturated fatty acids, linoleic acid (i.e. a decrease from ~16% to <4%) and linolenic acid (a decrease from ~35% to <10%).
( Jiang et al., 2016 )

SDN1
CRISPR/Cas

University of Nebraska
University of California, USA

Increased levels of oleic acid and alpha-linolenic acid. Camelina is a low-input oilseed crop. It is necessary to ameloriate fatty acid composition in oils to meet different application requirements.
( Ozseyhan et al., 2018 )

SDN1
CRISPR/Cas

Montana State University, USA

Increased levels of oleic acid, decreased levels of fatty acids.
( Morineau et al., 2016 )

SDN1
CRISPR/Cas

Université Paris-Saclay, France

Lower oil content and altered fatty acid composition. Most commercially produced oil seeds synthesize only a relatively small range of fatty acids, offering limited functionality.
( Aznar-Moreno et al., 2017 )

SDN1
CRISPR/Cas

Kansas State University, USA

Reduced glucosinolate levels. Glucosinolates are anti-nutrients that can cause reduced performance and impairment of kidney and liver functions of livestock.
( Hölzl et al., 2022 )

SDN1
CRISPR/Cas

University of Bonn
Leibniz Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben, Germany

Traits related to increased plant yield and growth

Induced erect leaf habit and shoot growth for a more efficient light penetration into lower canopy layers.
( Fladung et al., 2021 )

SDN1
CRISPR/Cas

Thünen Institute of Forest Genetics, Germany

Early flowering. Certain mutants also showed following phenotypes: determinate flowering, shorter stature and/or basal branching.
(Bellec et al., 2022)

SDN1
CRISPR/Cas

Université Paris-Saclay, France

Increased formation of adventitious roots (ARs). The formation of ARs is extremely important to the large-scale vegetative propagation of elite genotypes in many economically important woody species.
( Ran et al., 2023 )

SDN1
CRISPR/Cas

Nanjing Forestry University
Yangzhou University, China

More and longer lateral roots, more xylem and increased development of secondary vascular tissues: plants more suitable for biofuel and bioenergy production.
(An et al., 2023)

SDN1
CRISPR/Cas

Zhejiang A &
F University, China

Traits related to industrial utilization

35% reduction in lignin. Fourfold increase in cellulose-to-glucose conversion upon limited saccharification. Efficient saccharification is hindered by the presence of lignin in the secondary-thickened cell walls.
( de Vries et al., 2021 )

SDN1
CRISPR/Cas

Ghent University
VIB Center for Plant Systems Biology, Belgium

Reduced lignin content and increased sugar release upon saccharification.
( De Meester et al., 2021 )

SDN1
CRISPR/Cas

Ghent University
VIB Center for Plant Systems Biology, Belgium

Improved saccharification efficiency by an altered cell wall architecture.
( Nayeri et al., 2022 )

SDN1
CRISPR/Cas

Shahid Beheshti University
University of Tabriz, Iran

Tailoring poplar lignin without yield penalty. Reduced recalcitrance.
( De Meester et al., 2020 )

SDN1
CRISPR/Cas

Ghent University
VIB Center for Plant Systems Biology
VIB Metabolomics Core, Belgium

Increased monounsaturated fatty acid contents (MUFAs). Due to their higher thermal-oxidative stability and viscosity relative to other common fatty acids, MUFAs are preferred for industrial uses, for example as biolubricants and biodiesel fuels.
( Lee et al., 2021 )

SDN1
CRISPR/Cas

National Institute of Agricultural Sciences
Korea Advanced Institute of Science and Technology
Chonnam National University
Plant Engineering Research Institute, South Korea

Stem wood discoloration due to lignin reduction.
( Zhou et al., 2015 )

SDN1
CRISPR/Cas

University of Georgia, USA

Complete reproductive sterility to prevent the spread of highly domesticated, exotic or genetically modified organisms into wild populations.
( Azeez et al., 2021 )

SDN1
CRISPR/Cas

Michigan Technological University, USA

Modified wood composition with traits desirable for fiber pulping and lower carbon emissions. The edited wood could bring efficiencies, bioeconomic opportunities and environmental benefits.
( Sulis et al., 2023 )

SDN1
CRISPR/Cas

North Carolina State University
University of Illinois at Urbana-Champaign, USA
Beihua University
Northeast Forestry University, China

Enhanced oil accumulation in the seed.
( Cai et al., 2024 )

SDN1
CRISPR/Cas

Brookhaven National Laboratory
Stony Brook University
Montana State University, USA

Traits related to herbicide tolerance

Glyphosate resistance.
( Ortega et al., 2018 )

SDN2
CRISPR/Cas

New Mexico State University, USA

Traits related to product color/flavour

Albino phenotype
( Fan et al., 2015 )

SDN1
CRISPR/Cas

Southwest University
Chinese Academy of Sciences, China

Traits categories

Genome Editing Technique

Countries

Plant

Sdn Type

Traits related to biotic stress tolerance

Traits related to abiotic stress tolerance

Traits related to improved food/feed quality

Traits related to increased plant yield and growth

Traits related to industrial utilization

Traits related to herbicide tolerance

Traits related to product color/flavour