genome search | EU-SAGE

Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 35 results

Traits related to biotic stress tolerance

High resistance to powdery mildew under semi-commercial growth conditions.
( Shnaider et al., 2022 )

SDN1
CRISPR/Cas

Agricultural Research Organization Volcani Center, Israel

Bacterial resistance: Enhanced resistance to Xanthomonas campestris pv. musacearum, causing Bananas Xanthomonas wilt (BXW). Overall economic losses caused by Xanthomonas campestris were estimated at 2-8 billion USD over a decade.
(Tripathi et al., 2021)

SDN1
CRISPR/Cas

International Institute of Tropical Agriculture (IITA), Kenya

Virus resistance: Immunity to cucumber vein yellowing virus infection (Ipomovirus) and resistance to the potyviruses Zucchini yellow mosaic virus and Papaya ring spot mosaic virus.
(Chandrasekaran et al., 2016)

SDN1
CRISPR/Cas

Volcani Center, Israel

Viral resistance: increased control on viral pathogen Banana streak virus (BSV). The BSV integrates in the banana host genome as endogenous BSV (eBSV). When banana plants are stressed, the eBSV produces infectious viral particles and thus the plant develops disease symptoms.
(Tripathi et al., 2019)

SDN1
CRISPR/Cas

International Institute of Tropical Agriculture (IITA), Kenya
University of California, USA

Viral resistance: Increased resistance against watermelon mosaic virus (WMV), papaya ringspot virus (PRSV), and zucchini yellow mosaic virus (ZYMV).
(Fidan et al., 2023)

SDN1
CRISPR/Cas

Akdeniz University
Research and Development Department AD ROSSEN Seeds, Turkey

Fungal resistance: broad-spectrum stress tolerance including Pseudoperonospora cubernsis (P. cubensis) resistance. P. cubensis is the causal agent of cucurbit downy mildew, responsible for devastating losses worldwide of cucumber, cantaloupe, pumpkin, watermelon and squash.
(Dong et al., 2023)

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China
University of California, USA

Bacterial resistance: resistance against banana Xanthomonas wilt (BXW) disease, caused by Xanthomonas campestris pv. musacearum. BXW forms a great threat to banana cultivation in East and Central Africa.
(Ntui et al., 2023)

SDN1
CRISPR/Cas

International Institute of Tropical Agriculture, Kenya

Fungal resistance: increased resistance against powdery mildew, a destructive disease that threatens cucumber production globally.
(Dong et al., 2023)

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China
University of California Davis, USA
Wageningen University &
Research, The Netherlands

Traits related to abiotic stress tolerance

Improved drought and salt tolerance.
( Zhang et al., 2023 )

SDN1
CRISPR/Cas

Northeast Forestry University
Chinese Academy of Forestry
Chinese Academy of Sciences
Nanjing Forestry University, China

Broad-spectrum stress tolerance: enhanced low temperature, salinity, Pseudoperonospora cubensis and water-deficit tolerance.
(Dong et al., 2023)

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China
University of California, USA

Traits related to improved food/feed quality

Boosted cytokinin biosynthesis and elevated cucumber fruit wart formation. Warty fruit is an important quality trait that greatly affects market value and fruit appearance.
( Wang et al., 2022 )

SDN1
CRISPR/Cas

China Agricultural University, China

Regulate cucumber fruit wart formation. Warty fruit in cucumber is an important quality trait that greatly affects fruit appearance.
( Wang et al., 2021 )

SDN1
CRISPR/Cas

China Agricultural University, China

Removing the major allergen to tackle food allergies.
( Assou et al., 2021 )

SDN1
CRISPR/Cas

Leibniz Universität Hannover
Technische Universität Braunschweig, Germany

Generation of beta-carotene-enriched banana fruits. Carotenoids, the source of pro vitamin A, are an essential component of dietary antioxidants. Low intakes and poor bioavailability of provitamine A from the vegetarian diet are considered the main reasons for the widespread prevalence of Vitamine A deficiency.
( Kaur et al., 2020 )

SDN1
CRISPR/Cas

Ministry of Science and Technology (Government of India)
Panjab University, India

Nattokinase (NK) producing cucumber. NK is effective in the prevention and treatment of cardiovascular disease.
( Ni et al., 2023 )

SDN2
CRISPR/Cas

Xuzhou University of Technology
Nankai University, China

Seeds low in glucosinolate content and other plant parts high in glucosinolate levels. Glucosinolates are anti-nutrients that can cause reduced performance and impairment of kidney and liver functions of livestock, they also play a role in plant defence.
( Mann et al., 2023 )

SDN1
CRISPR/Cas

National Institute of Plant Genome Research
University of Delhi South Campus, India

Traits related to increased plant yield and growth

Semi-dwarf phenotype. High varieties are challenged by weak lodging and damages caused by storms, dwarf varieties are suitable for mechanized plant maintenance and fruit harvesting.
( Shao et al., 2020 )

SDN1
CRISPR/Cas

Guangdong Academy of Agricultural Sciences
Hunan Agricultural University
Chinese Academy of Sciences
University of Chinese Academy of Sciences, China
University of Florida, USA

Only female flowers. Allows earlier production of hybrids, higher yield, and more concentrated fruit set.
( Hu et al., 2017 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences,
China

Increased spine density. The “numerous spines (ns)” cucumber varieties are popular in Europe and West Asia.
( Liu et al., 2022 )

SDN1
CRISPR/Cas

Chinese Academy of Agricultural Sciences, China

Increased seed number per silique, which increases the mustard yield per plant.
( Wang et al., 2021 )

SDN1
CRISPR/Cas

Huazhong Agricultural University, China

Induced erect leaf habit and shoot growth for a more efficient light penetration into lower canopy layers.
( Fladung et al., 2021 )

SDN1
CRISPR/Cas

Thünen Institute of Forest Genetics, Germany

Increased formation of adventitious roots (ARs). The formation of ARs is extremely important to the large-scale vegetative propagation of elite genotypes in many economically important woody species.
( Ran et al., 2023 )

SDN1
CRISPR/Cas

Nanjing Forestry University
Yangzhou University, China

Dwarf phenotype to increase yield.
( Zhou et al., 2023 )

SDN1
CRISPR/Cas

Nanchang University
Jiangxi Academy of Agricultural Sciences, China

More and longer lateral roots, more xylem and increased development of secondary vascular tissues: plants more suitable for biofuel and bioenergy production.
(An et al., 2023)

SDN1
CRISPR/Cas

Zhejiang A &
F University, China

Traits related to industrial utilization

35% reduction in lignin. Fourfold increase in cellulose-to-glucose conversion upon limited saccharification. Efficient saccharification is hindered by the presence of lignin in the secondary-thickened cell walls.
( de Vries et al., 2021 )

SDN1
CRISPR/Cas

Ghent University
VIB Center for Plant Systems Biology, Belgium

Reduced lignin content and increased sugar release upon saccharification.
( De Meester et al., 2021 )

SDN1
CRISPR/Cas

Ghent University
VIB Center for Plant Systems Biology, Belgium

Improved saccharification efficiency by an altered cell wall architecture.
( Nayeri et al., 2022 )

SDN1
CRISPR/Cas

Shahid Beheshti University
University of Tabriz, Iran

Tailoring poplar lignin without yield penalty. Reduced recalcitrance.
( De Meester et al., 2020 )

SDN1
CRISPR/Cas

Ghent University
VIB Center for Plant Systems Biology
VIB Metabolomics Core, Belgium

Stem wood discoloration due to lignin reduction.
( Zhou et al., 2015 )

SDN1
CRISPR/Cas

University of Georgia, USA

Complete reproductive sterility to prevent the spread of highly domesticated, exotic or genetically modified organisms into wild populations.
( Azeez et al., 2021 )

SDN1
CRISPR/Cas

Michigan Technological University, USA

Modified wood composition with traits desirable for fiber pulping and lower carbon emissions. The edited wood could bring efficiencies, bioeconomic opportunities and environmental benefits.
( Sulis et al., 2023 )

SDN1
CRISPR/Cas

North Carolina State University
University of Illinois at Urbana-Champaign, USA
Beihua University
Northeast Forestry University, China

Traits related to product color/flavour

Albino phenotype
( Fan et al., 2015 )

SDN1
CRISPR/Cas

Southwest University
Chinese Academy of Sciences, China

Albinism and dwarfing.
( Naim et al., 2018 )

SDN1
CRISPR/Cas

Queensland University of Technology, Australia

Albino phenotype.
( Kaur et al., 2017 )

SDN1
CRISPR/Cas

National Agri-Food Biotechnology Institute (NABI), India

Traits related to storage performance

Increased shelf-life. Banana fruit has a high economic importance but will ripen and decay in one week after exogenous ethylene induction. Fast ripening limits its storage, transportation and marketing.
( Hu et al., 2021 )

SDN1
CRISPR/Cas

Guangdong Academy of Agricultural Sciences
Guangdong Laboratory for Lingnan Modern Agriculture, China

Traits categories

Genome Editing Technique

Countries

Plant

Sdn Type

Traits related to biotic stress tolerance

Traits related to abiotic stress tolerance

Traits related to improved food/feed quality

Traits related to increased plant yield and growth

Traits related to industrial utilization

Traits related to product color/flavour

Traits related to storage performance