genome search | EU-SAGE

Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Displaying 28 results

Traits related to industrial utilization

Male sterility.
( Djukanovic et al., 2013 )

I-CreI

DuPont/Pioneer Agricultural Biotechnology
Precision Biosciences, USA

Rapid generation of male sterile (MS) bread wheat. MS is an important tool in creating hybrid crop varieties that provide a yield advantage over traditional varieties by harnessing heterosis.
( Singh et al., 2021 )

SDN1
CRISPR/Cas

DuPont Pioneer, USA

Generate self-compatible diploid potato lines for the application of efficient breeding methods.
( Enciso-Rodriguez et al., 2021 )

SDN1
CRISPR/Cas

Michigan State University, USA

Generating male sterility lines (MLS). Using MLS in hybrid seed production reduces costs and ensures high purity of the varieties because it does not produce pollen and has exserted stigmas.
( Jung et al., 2020 )

SDN1
CRISPR/Cas

Hankyong National University
Hanyang University
Sunchon National University
Chungbuk National University
Tomato Research Center, South Korea

Rubber biosynthesis. To accelerate the domestication of Taraxacum kok-saghyz (TK), a plant notable for its ability to produce high molecular weight rubber in its roots and which might be an alternative source of natural rubber.
( Iaffaldano et al., 2016 )

SDN1
CRISPR/Cas

Ohio Agricultural Research and Development Center, USA

Reduced lignin content and S (syringyl lignin)/G (guaiacyl lignin) (S/G) ratio alteration to reduce cell wall recalcitrance and improve bioethanol production. Lignin is a major component of secondary cell walls and contributes to the recalcitrance problem during fermentation.
( Park et al., 2021 )

SDN1
CRISPR/Cas

The Samuel Roberts Noble Foundation
BioEnergy Science Center
University of Tennessee, USA

Enhanced oil accumulation in the seed.
( Cai et al., 2024 )

SDN1
CRISPR/Cas

Brookhaven National Laboratory
Stony Brook University
Montana State University, USA

Bio-fuel production: decreased lignin content improves cell wall composition for production of bio-ethanol.
(Laksana et al., 2024)

SDN1
CRISPR/Cas

Burapha University Sakaeo Campus
Kasetsart University, Thailand

Accumulate low levels of alkaloids. Nicotine is the most abundant alkaloid produced in tobacco plants. Switching to cigarettes containing levels of nicotine below the level of sustaining an addiction response will smoke less and/or find it easier to quit. Possibly, the US Food and Drug Administration (FDA) may mandate such reductions in future cigarette products.
( Smith et al., 2022 )

SDN1
CRISPR/Cas

North Carolina State University, USA

Complete reproductive sterility to prevent the spread of highly domesticated, exotic or genetically modified organisms into wild populations.
( Azeez et al., 2021 )

SDN1
CRISPR/Cas

Michigan Technological University, USA

Delayed flowering time.
( Hong et al., 2021 )

SDN1
CRISPR/Cas

National Institute of Agricultural Sciences, South Korea

Bio-fuel production: Reduced lignin content and improved sugar release.
(Park et al., 2017)

SDN1
CRISPR/Cas

Noble Research Institute, USA

Modified wood composition with traits desirable for fiber pulping and lower carbon emissions. The edited wood could bring efficiencies, bioeconomic opportunities and environmental benefits.
( Sulis et al., 2023 )

SDN1
CRISPR/Cas

North Carolina State University
University of Illinois at Urbana-Champaign, USA
Beihua University
Northeast Forestry University, China

Higher haploid induction rate. Haploid induction allows formation of doubled haploids, which can be used to rapidly fix genetic information.
( Jang et al., 2023 )

SDN1
CRISPR/Cas

Chonnam National University
Pusan National University
Kyung Hee University, South Korea

Bioethanol production: Improved saccharification efficiency without compromising biomass yield.
(Kannan et al., 2017)

SDN1
TALENs

University of Florida
Novozymes North America Inc, USA
Korea Institute of Science and Technology (KIST), South Korea

Stem wood discoloration due to lignin reduction.
( Zhou et al., 2015 )

SDN1
CRISPR/Cas

University of Georgia, USA

Early-flowering.
( Jeong et al., 2021 )

SDN1
CRISPR/Cas

Department of Biological Science
Seoul National University
Chungnam National University
Institute for Basic Science
Kangwon National University
Kyunghee University, South Korea

Bio-fuel production: Reduced lignin content, improves cell wall composition for production of bio-ethanol.
(Jung et al., 2016)

SDN1
TALENs

Korea University, South Korea
University of Florida, USA

Asexual propagation trough seeds. Induction of apomeiosis, mitosis instead of meiosis. This proces leads to the production of genetically identical seeds, serving many applications in plant breeding.
( Khanday et al., 2019 )

SDN1
CRISPR/Cas

University of California
Innovative Genomics Institute
Iowa State University, USA
Université Paris-Saclay, France

Increased monounsaturated fatty acid contents (MUFAs). Due to their higher thermal-oxidative stability and viscosity relative to other common fatty acids, MUFAs are preferred for industrial uses, for example as biolubricants and biodiesel fuels.
( Lee et al., 2021 )

SDN1
CRISPR/Cas

National Institute of Agricultural Sciences
Korea Advanced Institute of Science and Technology
Chonnam National University
Plant Engineering Research Institute, South Korea

Enhanced biological nitrogen fixation to reduce the use of inorganic nitrogen fertilizers. Enhanced biofilm formation of soil diazotrophic bacteria by modified root microbiome structure.
( Yan et al., 2022 )

SDN1
CRISPR/Cas

University of California
Bayer Crop Science, USA

Trait stacking. Modern agriculture demands crops carrying multiple traits.
( Ainley et al., 2013 )

SDN1
ZFN

Dow AgroSciences LLC
Sangamo BioSciences, Inc., USA

Generation of male-sterile hexaploid wheat lines for use in hybrid seed production. The development and adoption of hybrid seed technology have led to dramatic increases in agricultural productivity.
( Okada et al., 2019 )

SDN1
CRISPR/Cas

The University of Adelaide, Australia
Huaiyin Normal University, China

Generating male sterility lines (MLS). Using MLS in hybrid seed production for monoclinous crops reduces costs and ensures high purity of the varieties because it does not produce pollen and has exserted stigmas.
( Svitashev et al., 2015 )

SDN1
CRISPR/Cas

DuPont Pioneer, USA

Induction of haploid plants and a reduced seed set for rice breeding.
( Yao et al., 2018 )

SDN2
CRISPR/Cas

ZhongGuanCun Life Science Park, China
Syngenta India Limited
Technology Centre
Medchal Mandal, India
Syngenta Crop Protection
LLC
Research Triangle Park, USA

Improve biofuel production by mediating lignin modification. Lignocellulosic biomasses are an abundant renewable source of carbon energy. Heterogenous properties of lignocellulosic biomass and intrinsic recalcitrance caused by cell wall lignification lower the biorefinery efficiency. Reduced lignin content is desired.
( Lee et al., 2021 )

SDN1
CRISPR/Cas

Korea Institute of Science and Technology (KIST)
University of Science and Technology (UST)
Daejeon, South Korea

Accelerated abscission. Plant organ abscission is a process important for development and reproductive success,
( Liu et al., 2022 )

SDN1
CRISPR/Cas

Shenyang Agricultural University
Key Laboratory of Protected Horticulture of Ministry of Education, China
University of California at Davis
Crops Pathology and Genetic Research Unit, USA

Hairy root transformation. Hairy roots play a role in multiple processes, ranging from recombinant protein production and metabolic engineering to analyses of rhizosphere physiology and biochemistry.
( Ron et al., 2014 )

SDN1
CRISPR/Cas

University of California
Emory University, USA
University of Cambridge, UK

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Traits related to industrial utilization