Genome-editing techniques are promising tools in plant breeding. To facilitate a more comprehensive understanding of the use of genome editing, EU-SAGE developed an interactive, publicly accessible online database of genome-edited crop plants as described in peer-reviewed scientific publications.
The aim of the database is to inform interested stakeholder communities in a transparent manner about the latest evidence about the use of genome editing in crop plants. Different elements including the plant species, traits, techniques, and applications can be filtered in this database.
Regarding the methodology, a literature search in the bibliographic databases and web pages of governmental agencies was conducted using predefined queries in English. Identifying research articles in other languages was not possible due to language barriers. Patents were not screened.
Peer-reviewed articles were screened for relevance and were included in the database based on pre-defined criteria. The main criterium is that the research article should describe a research study of any crop plant in which a trait has been introduced that is relevant from an agricultural and/or food/feed perspective. The database does neither give information on the stage of development of the crop plant, nor on the existence of the intention to develop the described crop plants to be marketed.
This database will be regularly updated. Please contact us via the following webpage in case you would like to inform us about a new scientific study of crops developed for market-oriented agricultural production as a result of genome editing

Genome Editing Technique

Plant

Sdn Type

Displaying 27 results

Traits related to biotic stress tolerance

Fungal resistance: increased resistance to Erysiphe necator, causing powdery mildew in grape cultivar. The pathogen infects all green tissues and berries, leading to dramatic losses in yield and berry quality.
(Malnoy et al., 2016)
SDN1
CRISPR/Cas
Fondazione Edmund Mach, Italy
ToolGen Inc.
Institute for Basic Science
Seoul National University
South Korea
Viral resistance: Resistance against Grapevine leafroll-associated virus 3 (GLRaV-3), which is one of the causal agents of grapevine leafroll disease (GLD). GLD severely impacts grapevine production.
(Jiao et al., 2022)

CRISPR/Cas
Northwest A&
F University, China
Fungal resistance: enhanced resistance to powdery mildew (Erysiphe necator), a major fungal disease, threatening one of the most economically valuable horticular crops.
(Wan et al., 2020)
SDN1
CRISPR/Cas
Ministry of Agriculture, China
Northwest A&
F University
University of Maryland College Park, USA
Fungal resistance: increased resistance to Botrytis cinerea.
(Wang et al., 2018)
SDN1
CRISPR/Cas
Northwest A&
F University and Ministry of Agriculture, China
Viral resistance: increased resistance to turnip mosaic virus (TuMV).
(Lee et al., 2023)
SDN1
CRISPR/Cas
Rural Development Administration
Advanced Institute for Science and Technology, South Korea
North Carolina State University, USA
Fungal resistance: effective reduction of susceptibility against downy mildew by increasing salicylic acid levels. The pathogen can devastate individual vineyards and in some cases also affect production from entire regions.
(Giacomelli et al., 2023)
SDN1
CRISPR/Cas
Research and Innovation Centre
Fondazione Edmund Mach, Italy
Enza Zaden
Hudson River Biotechnology, The Netherlands
Fungal resistance: Decreased susceptibility to Plasmopara viticola, the causing agent of the grapevine downy mildew.
(Djennane et al., 2023)
SDN1
CRISPR/Cas
Université de Strasbourg
Institut Jean-Pierre Bourgin (IJPB), France

Traits related to abiotic stress tolerance

Regulated circadian clock: circadian clock measures and conveys day length information to control rhythmic hypocotyl growth in photoperiodic conditions, to achieve optimal fitness. Mutants showed longer hypocotyls, lower core circadian clock morning component mRNA and protein levels, and a shorter circadian rhythm. Exposure to high temperature due to global warming.
(Kim et al., 2022)
SDN1
CRISPR/Cas
National Institute of Agricultural Science
Korea Polar Research Institute
Seoul National University College of Medicine, South Korea
Reduced stomatal density. Intrinsic water-use efficiency was significantly impacted under both well-watered and drought conditions, making reduced stomatal density as a preferable trait.
( Clemens et al., 2022 )
SDN1
CRISPR/Cas
University of California
San Diego State University, USA

Traits related to improved food/feed quality

Low tartaric acid.
( Ren et al., 2016 )
SDN1
CRISPR/Cas
University of Chinese Academy of Sciences
Chinese Academy of Sciences, China
Promoted anthocyanin accumulation. Anthocyanins are plant secondary metabolites with a variety of biological functions.
( Tu et al., 2022 )
SDN1
CRISPR/Cas
Northwest A&
F University, China
Increased vitamin C content, increased oxidation stress tolerance and increased ascorbate content.
( Zhang et al., 2018 )
SDN1
CRISPR/Cas
Chinese Academy of Sciences, China

Traits related to increased plant yield and growth

High temperature germination. Large increases in the maximum temperature for seed germination to allow for the cultivation of the crop in production areas with higher temperature.
( Bertier et al., 2018 )
SDN1
CRISPR/Cas
University of California, USA
Bushy phenotype and increased tiller production.
( Liu et al., 2017 )
SDN1
CRISPR/Cas
Iowa State University, USA
Improve biomass yield and salinity tolerance.
( Guan et al., 2020 )
SDN1
CRISPR/Cas
China Agricultural University
Shandong institute of agricultural sustainable development
Beijing Sure Academy of Biosciences, China
Oklahoma State University, USA
Enhanced photosynthesis and decreased leaf angles for improved plant architecture and high yields.
( An et al., 2022 )
SDN1
CRISPR/Cas
Huazhong Agricultural University, China
Increased leaf yield of lettuce by delaying the onset of flowering.
( Choi et al., 2022 )
SDN1
CRISPR/Cas
Korea Research Institute of Bioscience and Biotechnology
Korea University of Science and Technology, South Korea
Significantly improved photosynthesis and decreased leaf angles. The plant architecture is ideal for dense planting.
( An et al., 2022 )
SDN1
CRISPR/Cas
Huazhong Agricultural University, China
Delay in the appearance of flower buds and increased yield.
( Beracochea et al., 2023 )
SDN1
CRISPR/Cas
Consejo Nacional de Investigaciones Científicas Y Técnicas (CONICET)
Instituto Nacional de Tecnología Agropecuaria (INTA), Argentina
Delayed bolting.
( Shin et al., 2022 )
SDN1
CRISPR/Cas
Kyung Hee University, South Korea
Delayed bolting.
( Shin et al., 2022 )
SDN1
CRISPR/Cas
Kyung Hee University, South Korea
Early bolting and flowering.
( Wang et al., 2023 )
SDN1
CRISPR/Cas
South China Agricultural University, China
Butterhead plant architecture.
( Xie et al., 2023 )
SDN1
CRISPR/Cas
Huazhong Agricultural University
Wuhan Academy of Agricultural Sciences, China

Traits related to industrial utilization

Early-flowering.
( Jeong et al., 2021 )
SDN1
CRISPR/Cas
Department of Biological Science
Seoul National University
Chungnam National University
Institute for Basic Science
Kangwon National University
Kyunghee University, South Korea
Delayed flowering time.
( Hong et al., 2021 )
SDN1
CRISPR/Cas
National Institute of Agricultural Sciences, South Korea
Bio-fuel production: Reduced lignin content and improved sugar release.
(Park et al., 2017)
SDN1
CRISPR/Cas
Noble Research Institute, USA
Reduced lignin content and S (syringyl lignin)/G (guaiacyl lignin) (S/G) ratio alteration to reduce cell wall recalcitrance and improve bioethanol production. Lignin is a major component of secondary cell walls and contributes to the recalcitrance problem during fermentation.
( Park et al., 2021 )
SDN1
CRISPR/Cas
The Samuel Roberts Noble Foundation
BioEnergy Science Center
University of Tennessee, USA